Gene
APOE
apolipoprotein E
Explore in graph →CI-GENE-00011081HGNC:613 ENSG00000130203 NCBI 348 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Adrenocortical Carcinoma (TCGA, Firehose Legacy) acc_tcga | Adrenal Cortical Carcinoma | Ssm | 8 | 90 | 8.9% | 109 | cbioportal |
| Intrahepatic Cholangiocarcinoma (JHU, Nat Genet 2013) chol_jhu_2013 | Cholangiocarcinoma | Ssm | 2 | 40 | 5% | 29 | cbioportal |
| Metastatic Pancreatic Adenocarcinoma (PRINCE Trial, Nat Med. 2022) - iAtlas Harmonized paad_iatlas_prince_2022 | Pancreatic Adenocarcinoma | Ssm | 4 | 93 | 4.3% | 113 | cbioportal |
| Pediatric Acute Lymphoid Leukemia - Phase II (TARGET, 2018) all_phase2_target_2018_pub | B Lymphoblastic Leukemia/Lymphoma | Ssm | 2 | 150 | 1.3% | 17 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.