Gene
ANGPTL2
angiopoietin like 2
Explore in graph →CI-GENE-00010745HGNC:490 ENSG00000136859 NCBI 23452 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28162975
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Pheochromocytoma and Paraganglioma (TCGA, Cell 2017) pcpg_tcga_pub | unmapped | Ssm | 2 | 178 | 1.1% | 62 | cbioportal |
| Pheochromocytoma and Paraganglioma (TCGA, PanCancer Atlas) pcpg_tcga_pan_can_atlas_2018 | unmapped | Ssm | 1 | 178 | 0.6% | 194 | cbioportal |
| Miscellaneous Neuroepithelial Tumor (TCGA GDC, 2025) mnet_tcga_gdc | Central Nervous System Neuroepithelial Neoplasm of Uncertain Origin | Ssm | 1 | 183 | 0.5% | 150 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.