Gene
ALPK3
alpha kinase 3
Explore in graph →CI-GENE-00010654HGNC:17574 ENSG00000136383 NCBI 57538 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (22)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26997480
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Metastatic Melanoma (UCLA, Cell 2016) - iAtlas Harmonized mel_iatlas_hugo_ucla_2016 | Melanoma | Ssm | 8 | 27 | 29.6% | 148 | cbioportal |
| Melanoma (Broad/Dana Farber, Nature 2012) skcm_broad_dfarber | Cutaneous Melanoma | Ssm | 6 | 26 | 23.1% | 46 | cbioportal |
| Primary Central Nervous System Lymphoma (Mayo Clinic, Clin Cancer Res 2015) pcnsl_mayo_2015 | Primary Central Nervous System Lymphoma | Ssm | 1 | 10 | 10% | 143 | cbioportal |
| Triple Negative Breast Cancer (DLDCCC, Cancer Discov 2022) brca_dldccc_2022 | Invasive Breast Carcinoma | Ssm | 6 | 75 | 8% | 125 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.