Gene
ALOX12
arachidonate 12-lipoxygenase, 12S type
Explore in graph →CI-GENE-00000960HGNC:429 ENSG00000108839 NCBI 239 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Kidney Renal Clear Cell Carcinoma (TCGA, Firehose Legacy) kirc_tcga | Clear Cell Renal Cell Carcinoma | Ssm | 16 | 451 | 3.5% | 96 | cbioportal |
| Intrahepatic Cholangiocarcinoma (JHU, Nat Genet 2013) chol_jhu_2013 | Cholangiocarcinoma | Ssm | 1 | 40 | 2.5% | 157 | cbioportal |
| Pancreatic Neuroendocrine Tumors (Multi-Institute, Nature 2017) panet_arcnet_2017 | Pancreatic Neuroendocrine Tumor | Ssm | 2 | 98 | 2% | 47 | cbioportal |
| Ewing Sarcoma (Institut Curie, Cancer Discov 2014) es_iocurie_2014 | Ewing Sarcoma | Ssm | 1 | 112 | 0.9% | 94 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.