Gene
AKAP4
A-kinase anchoring protein 4
Explore in graph →CI-GENE-00000810HGNC:374 ENSG00000147081 NCBI 8852 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (9)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33863915
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Metaplastic Breast Cancer (MSK,NPJ Breast Cancer 2021) mbc_msk_2021 | Breast Metaplastic Carcinoma | Ssm | 1 | 5 | 20% | 29 | cbioportal |
| Diffuse Large B-Cell Lymphoma, NOS (TCGA GDC, 2025) dlbclnos_tcga_gdc | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 2 | 36 | 5.6% | 163 | cbioportal |
| Neuroblastoma (Broad, Nat Genet 2013) nbl_broad_2013 | Neuroblastoma | Ssm | 3 | 240 | 1.3% | 61 | cbioportal |
| Brain Lower Grade Glioma (TCGA, PanCancer Atlas) lgg_tcga_pan_can_atlas_2018 | Diffuse Glioma | Ssm | 6 | 514 | 1.2% | 193 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.