Gene
AHCYL2
adenosylhomocysteinase like 2
Explore in graph →CI-GENE-00000730HGNC:22204 ENSG00000158467 NCBI 23382 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (13)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 34635660
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| RAD51B Associated Mixed Cancers (MSK, NPJ Breast Cancer 2021) mixed_msk_tcga_2021 | unmapped | Ssm | 1 | 4 | 25% | 133 | cbioportal |
| Metastatic Renal Clear Cell Carcinoma (Phase 1 Biomarker Trial, Clin Cancer Res. 2016) - iAtlas Harmonized ccrcc_iatlas_choueiri_2016 | Clear Cell Renal Cell Carcinoma | Ssm | 2 | 16 | 12.5% | 31 | cbioportal |
| Upper Tract Urothelial Carcinoma (IGBMC, Genome Biology 2021) utuc_igbmc_2021 | Renal Pelvis and Ureter Urothelial Carcinoma | Ssm | 2 | 30 | 6.7% | 54 | cbioportal |
| Diffuse Large B-Cell Lymphoma, NOS (TCGA GDC, 2025) dlbclnos_tcga_gdc | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 2 | 36 | 5.6% |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.