Gene
ADAM11
ADAM metallopeptidase domain 11
Explore in graph →CI-GENE-00000414HGNC:189 ENSG00000073670 NCBI 4185 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22138691
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Kidney Renal Clear Cell Carcinoma (BGI, Nat Genet 2012) kirc_bgi | Clear Cell Renal Cell Carcinoma | Ssm | 1 | 98 | 1% | 82 | cbioportal |
| Acute Myeloid Leukemia (TCGA, Firehose Legacy) laml_tcga | Acute Myeloid Leukemia | Ssm | 2 | 197 | 1% | 43 | cbioportal |
| Acute Myeloid Leukemia (TCGA, NEJM 2013) laml_tcga_pub | Acute Myeloid Leukemia | Ssm | 2 | 200 | 1% | 43 | cbioportal |
| Medulloblastoma (ICGC, Nature 2012) mbl_icgc | Medulloblastoma | Ssm | 1 | 125 | 0.8% | 73 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.