Gene
ADAM10
ADAM metallopeptidase domain 10
Explore in graph →CI-GENE-00000413HGNC:188 ENSG00000137845 NCBI 102 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24293293
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Acinar Cell Carcinoma of the Pancreas (JHU, J Pathol 2014) paac_jhu_2014 | Pancreatic Acinar Cell Carcinoma | Ssm | 2 | 23 | 8.7% | 52 | cbioportal |
| Bladder Urothelial Carcinoma (BGI, Nat Genet 2013) blca_bgi | Bladder Urothelial Carcinoma | Ssm | 3 | 99 | 3% | 166 | cbioportal |
| Liposarcoma (MSK, 2026) lipo_msk_2026 | Liposarcoma | Ssm | 2 | 277 | 0.7% | 116 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.