Gene
ACVRL1
activin A receptor like type 1
Explore in graph →CI-GENE-00000388HGNC:175 ENSG00000139567 NCBI 94 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 23622249
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Prostate Adenocarcinoma (Broad/Cornell, Cell 2013) prad_broad_2013 | Prostate Adenocarcinoma | Ssm | 2 | 57 | 3.5% | 41 | cbioportal |
| Uveal Melanoma (TCGA, Firehose Legacy) uvm_tcga | Uveal Melanoma | Ssm | 1 | 80 | 1.3% | 123 | cbioportal |
| Lung Adenocarcinoma (TSP, Nature 2008) luad_tsp | Lung Adenocarcinoma | Ssm | 2 | 163 | 1.2% | 95 | cbioportal |
| Breast Cancer (METABRIC, Nature 2012 & Nat Commun 2016) brca_metabric | Invasive Breast Carcinoma | Ssm | 13 | 2,433 | 0.5% | 148 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.