Gene
ACTR6
actin related protein 6
Explore in graph →CI-GENE-00000374HGNC:24025 ENSG00000075089 NCBI 64431 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 30742119
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Glioblastoma (Columbia, Nat Med. 2019) gbm_columbia_2019 | Diffuse Glioma | Ssm | 1 | 32 | 3.1% | 51 | cbioportal |
| Bladder Urothelial Carcinoma (BGI, Nat Genet 2013) blca_bgi | Bladder Urothelial Carcinoma | Ssm | 3 | 99 | 3% | 165 | cbioportal |
| Renal Clear Cell Carcinoma (UTokyo, Nat Genet 2013) ccrcc_utokyo_2013 | Clear Cell Renal Cell Carcinoma | Ssm | 2 | 106 | 1.9% | 182 | cbioportal |
| Neuroblastoma (AMC Amsterdam, Nature 2012) nbl_amc_2012 | Neuroblastoma | Ssm | 1 | 87 | 1.1% | 25 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.