Gene
ACLY
ATP citrate lyase
Explore in graph →CI-GENE-00000223HGNC:115 ENSG00000131473 NCBI 47 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (9)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33585982
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Cutaneous Neurofibroma Data Resource (CTF, Scientific Data 2021) nfib_ctf_biobank_2025 | Neurofibroma | Ssm | 6 | 38 | 15.8% | 61 | cbioportal |
| Normal Fibroblasts (UCSF, BioRxiv 2024) normal_skin_fibroblast_2024 | unmapped | Ssm | 2 | 18 | 11.1% | 20 | cbioportal |
| Intrahepatic Cholangiocarcinoma (Shanghai, Nat Commun 2014) ihch_smmu_2014 | Intrahepatic Cholangiocarcinoma | Ssm | 4 | 103 | 3.9% | 79 | cbioportal |
| Cholangiocarcinoma (ICGC, Cancer Discov 2017) chol_icgc_2017 | Cholangiocarcinoma | Ssm | 7 | 417 | 1.7% | 177 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.