Gene
ACAD8
acyl-CoA dehydrogenase family member 8
Explore in graph →CI-GENE-00000178HGNC:87 ENSG00000151498 NCBI 27034 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| HIV+ Tumor Molecular Characterization Project - Diffuse Large B-Cell Lymphoma CGCI-HTMCP-DLBCL | Diffuse Large B-Cell LymphomaCURATED_BROADER | Ssm | 19 | 50 | 38% | 11 | gdc |
| Esophageal Cancer-TRAP Project (MSK, Lancet Oncol 2020) egc_trap_msk_2020 | Gastroesophageal Junction Adenocarcinoma | Ssm | 2 | 31 | 6.5% | 141 | cbioportal |
| Pediatric Wilms' Tumor (TARGET, 2018) wt_target_2018_pub | Wilms Tumor | Ssm | 1 | 657 | 0.2% | 65 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.