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Drugs
One entity per molecule (INN preferred); brand names and development codes are aliases. Approvals are always shown with jurisdiction and indication.
820 drugs
| Drug | Kind | Mechanism | Approvals | Evidence items | Trials | Identifiers |
|---|---|---|---|---|---|---|
| JQ1 Compound | — | — | 0 | 1 | 0 | — |
| JW55 | Small Molecule | — | 0 | 1 | 0 | CHEMBL3753077 |
| K 252a | Small Molecule | — | 0 | 1 | 0 | C1382 · CHEMBL281948 |
| KG5 | — | — | 0 | 1 | 0 | — |
| KU-0060648 | — | — | 0 | 1 | 0 | — |
| Larotrectinib Regimen | — | — | 0 | 1 | 1 | C160074 |
| Lasofoxifene | Small Molecule | Estrogen receptor modulator | 0 | 1 | 2 | C80679 · CHEMBL328190 |
| Lifirafenib | Small Molecule | Serine/threonine-protein kinase B-raf inhibitor | 0 | 1 | 3 | C124995 · CHEMBL4209157 |
| Luminespib | Small Molecule | Heat shock protein HSP90 inhibitor | 0 | 1 | 23 | C71467 · CHEMBL252164 |
| Lumretuzumab | Monoclonal Antibody | Receptor tyrosine-protein kinase erbB-3 inhibitor | 0 | 1 | 3 | CHEMBL3707404 |
| Lysine | Small Molecule | Radioprotective agent | 0 | 1 | 0 | C29171 · CHEMBL8085 |
| MAP855 | — | — | 0 | 1 | 0 | — |
| Mcl-1 Inhibitor MIK665 | — | — | 0 | 1 | 2 | C133174 |
| MEK-1/MEKK-1 Inhibitor E6201 | — | — | 0 | 1 | 4 | C79848 |
| MEK Inhibitor GDC-0623 | — | — | 0 | 1 | 0 | C95738 |
| MEK Inhibitor REC-4881 | — | — | 0 | 1 | 3 | C84858 |
| Menin Inhibitor | — | — | 0 | 1 | 0 | C185877 |
| MET Tyrosine Kinase Inhibitor SGX523 | — | — | 0 | 1 | 2 | C74062 |
| Molibresib | Small Molecule | Bromodomain and extra-terminal motif (BET) inhibitor | 0 | 1 | 9 | C101538 · CHEMBL1232461 |
| Monensin | Small Molecule | — | 0 | 1 | 0 | C83971 · CHEMBL256105 |
| Monomethyl Auristatin E | — | — | 0 | 1 | 0 | C122637 |
| MRNA Vaccine | — | — | 0 | 1 | 0 | C172787 |
| MUC1-targeted Peptide GO-203-2C | — | — | 0 | 1 | 3 | C95722 |
| Multi-subtype Natural Human Leukocyte Interferon Alpha | — | — | 0 | 1 | 0 | C97509 |
| MVT Regimen | — | — | 0 | 1 | 5 | C10254 |
| Nano TACs | — | — | 0 | 1 | 0 | — |
| Naquotinib | Small Molecule | Epidermal growth factor receptor erbB1 inhibitor | 0 | 1 | 7 | C115110 · CHEMBL3663929 |
| NCT00137111 | — | — | 0 | 1 | 0 | — |
| Nedaplatin | Small Molecule | — | 0 | 1 | 28 | C61099 · CHEMBL3137685 |
| Niacinamide | Small Molecule | — | 0 | 1 | 10 | C2327 · CHEMBL1140 |
| Ningetinib | Small Molecule | Hepatocyte growth factor receptor inhibitor; Vascular endothelial growth factor receptor 2 inhibitor; Proto-oncogene tyrosine-protein kinase MER inhibitor; Tyrosine-protein kinase receptor FLT3 inhibitor; Tyrosine-protein kinase receptor UFO inhibitor | 0 | 1 | 1 | C214441 · CHEMBL3984441 |
| Not Applicable | — | — | 0 | 1 | 0 | — |
| NOTCH1 Antibody (PF-06293622) | — | — | 0 | 1 | 0 | — |
| NU7441 | — | — | 0 | 1 | 0 | — |
| Nutlin-3 | Small Molecule | — | 0 | 1 | 0 | CHEMBL191334 |
| NVP-AEW541 | Small Molecule | Insulin-like growth factor I receptor inhibitor | 0 | 1 | 0 | CHEMBL551064 |
| NVP-AST487 | Small Molecule | Tyrosine-protein kinase receptor FLT3 inhibitor; Tyrosine-protein kinase receptor RET inhibitor | 0 | 1 | 0 | CHEMBL574738 |
| O6-Benzylguanine | Small Molecule | — | 0 | 1 | 29 | C1306 · CHEMBL407874 |
| OICR-9429 | Small Molecule | — | 0 | 1 | 0 | CHEMBL3798846 |
| Omipalisib | Small Molecule | PI3-kinase class I inhibitor; Serine/threonine-protein kinase mTOR inhibitor | 0 | 1 | 1 | C88270 · CHEMBL1236962 |
| Onalespib | Small Molecule | Heat shock protein HSP90 inhibitor | 0 | 1 | 11 | C85454 · CHEMBL1214827 |
| Onartuzumab | Monoclonal Antibody | Hepatocyte growth factor receptor antagonist | 0 | 1 | 17 | C82348 · CHEMBL1743051 |
| Onatasertib | Small Molecule | Serine/threonine-protein kinase mTOR inhibitor | 0 | 1 | 5 | C92575 · CHEMBL3586404 |
| Paclitaxel Liposome | — | — | 0 | 1 | 16 | C2631 |
| Palliative Radiation Therapy | — | — | 0 | 1 | 0 | C116433 |
| Panitumumab Regimen | — | — | 0 | 1 | 0 | C160104 |
| Pan-Mutant-IDH1 Inhibitor Bay-1436032 | — | — | 0 | 1 | 2 | C131690 |
| Pan-RAF Inhibitor LY3009120 | Small Molecule | Serine/threonine-protein kinase B-raf inhibitor; Serine/threonine-protein kinase RAF inhibitor; Serine/threonine-protein kinase A-Raf inhibitor | 0 | 1 | 1 | C116861 · CHEMBL3577124 |
| PARP Inhibitor ABT-888 | — | — | 0 | 1 | 0 | — |
| PARP Inhibitor AZD2461 | — | — | 0 | 1 | 1 | C95201 |