Drug · Small Molecule
Vinblastine
CI-DRUG-00000662Explore in graph →CHEMBL159 Approved
Regulatory
Approvals (10)
Each record names the authority, jurisdiction, indication text and status. A drug approved in one jurisdiction for one indication is not 'approved' in general.
- Source
- Health Canada — Drug Product Database (DPD)
- Dataset
- Health Canada DPD
- Version
- dpd-2026-09-11
- Retrieved
- Sep 11, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- regulatory
- License
- Open Government Licence – Canada (https://open.canada.ca/en/open-government-licence-canada)
- Run
- ING-HEALTHCANADADPD-20260911-000001
| Jurisdiction · authority | Cancer | Indication | Status | Approval date | Source |
|---|---|---|---|---|---|
| CA Health Canada | — | Marketed in Canada as VINBLASTINE SULPHATE INJECTION (DIN 02401460) under ATC L01CA01 VINBLASTINE. Indications are not published in the Drug Product Database — see the Health Canada Product Monograph. | approvedsource: Marketed | Feb 8, 2013 | health-canada-dpd |
| CA Health Canada | — | Marketed in Canada as VINBLASTINE SULFATE INJECTION (DIN 02183056) under ATC L01CA01 VINBLASTINE. Indications are not published in the Drug Product Database — see the Health Canada Product Monograph. | approvedsource: Marketed | Apr 14, 1998 | health-canada-dpd |
| CA Health Canada | — | Marketed in Canada as VELBE 1MG/ML (DIN 00015431) under ATC L01CA01 VINBLASTINE. Indications are not published in the Drug Product Database — see the Health Canada Product Monograph. | withdrawnsource: Cancelled Post Marketsince Oct 2, 2000 |
Health Canada records are DIN-level: one row per marketed product (brand, strength, form). The Drug Product Database does not publish indications, so no cancer is stated for these rows, and a cancelled or dormant DIN is the status of that one product — not a withdrawal of the molecule.
Data updated 16 days agoSource updated unknown
Derived
Development pipeline
Most advanced stage across all cancers, then per top-level cancer reached through trial conditions or approval indications. Approval in any ingested jurisdiction outranks trial phase; counts are interventional studies.
| Scope | Stage | Max phase | Active | Recruiting | Phase 3 | Trials | Approvals | Jurisdictions | First approval | First trial |
|---|---|---|---|---|---|---|---|---|---|---|
| All cancers | Approved | Phase 4 | 29 | 13 | 48 | 141 | 10 | CA, US | Apr 29, 1987 | 1989-04 |
| Hodgkin Lymphoma | Approved | Phase 4 | 17 | 7 | 8 | 42 | 1 | US | Apr 29, 1987 | Jan 25, 1994 |
| Non-Hodgkin Lymphoma | Approved | Phase 3 | 1 | 1 | 1 | 3 | 1 | US | Apr 29, 1987 | 2003-01 |
| Kaposi Sarcoma | Approved | — | 0 | 0 | 0 | 0 | 1 | US |
Curated evidence
Clinical evidence (0)
CIViC items in which this therapy appears, grouped by cancer context, then molecular profile. 50 items per page.
Data not yet available
Clinical trials
Trials with this intervention (141)
Most recently updated first, 50 per page.
- Source
- ClinicalTrials.gov
- Dataset
- ClinicalTrials.gov API v2 studies
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00213278 | Phase 2 Study of Vinblastine in Children With Recurrent or Refractory Low Grade Glioma | completed | Phase 2 | 50 | The Hospital for Sick ChildrenOTHER | 1 | Nov 20, 2014 | clinicaltrials |
| NCT00520403 | A Study of Avastin (Bevacizumab) in Combination With Standard Therapy in Patients With Metastatic Renal Cell Cancer. | completed |