Subtype
Primary Central Nervous System Neoplasm
CI-CAN-00001432Explore in graph →
Non-malignant957 active trials5 approved drugs175 evidence items
- NCIt
- C102871
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Subtype
CI-CAN-00001432Explore in graph →
Clinical trials
3,294 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00667394 | Tandutinib Plus Bevacizumab to Treat Recurrent Brain Tumors | completed | Phase 2 | 42 | National Cancer Institute (NCI)NIH | 1 | Nov 5, 2015 | clinicaltrials |
| NCT00846456 | Safe Study of Dendritic Cell (DC) Based Therapy Targeting Tumor Stem Cells in Glioblastoma | completed | Phase 1 / Phase 2 | 20 | Oslo University HospitalOTHER | 0 | Oct 20, 2015 | clinicaltrials |
| NCT01138813 |
| Development of Magnetic Resonance Spectroscopy (MRS) Biomarkers of Tumor Metabolism (MK-0000-145)(MRS Tumor) |
| completed |
| — |
| 8 |
| Merck Sharp & Dohme LLCINDUSTRY |
| 0 |
| Oct 12, 2015 |
| clinicaltrials |
| NCT00369590 | VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide | completed | Phase 2 | 58 | National Cancer Institute (NCI)NIH | 1 | Oct 2, 2015 | clinicaltrials |
| NCT01119599 | RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma | completed | Phase 1 | 22 | National Cancer Institute (NCI)NIH | 1 | Sep 29, 2015 | clinicaltrials |
| NCT01111097 | Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain Tumors | completed | Phase 1 | 15 | University of FloridaOTHER | 1 | Sep 22, 2015 | clinicaltrials |
| NCT00704808 | Post Marketing Surveillance: Newly Diagnosed Glioblastoma Multiforme Treated With Radiotherapy/Temozolomide and Adjuvant Temozolomide (Study P04739) | completed | — | 180 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Sep 9, 2015 | clinicaltrials |
| NCT00725010 | Temozolomide in Concomitant Radiochemotherapy Followed by Sequential Temozolomide Chemotherapy - Observational Program (Study P04816) | completed | — | 64 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Sep 9, 2015 | clinicaltrials |
| NCT01462695 | Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma | completed | Phase 2 | 30 | National Cancer Institute (NCI)NIH | 3 | Aug 27, 2015 | clinicaltrials |
| NCT01102595 | Neo-adjuvant Treatment With Temozolomide and Bevacizumab Previous to Temozolomide Plus Radiation Plus Bevacizumab Therapy in Unresectable Glioblastoma | completed | Phase 2 | 102 | Grupo Español de Investigación en NeurooncologíaOTHER | 1 | Aug 26, 2015 | clinicaltrials |
| NCT00087451 | Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED) | completed | Phase 1 | 11 | Merck Sharp & Dohme LLCINDUSTRY | 1 | Aug 19, 2015 | clinicaltrials |
| NCT02286531 | Evaluation de O-(2-[18F]-Fluoroethyl)-L-Tyrosine, a New Tracer PET, in the Diagnosis of Low Grade Glioma(PET-FETII) | completed | N/A | 93 | University Hospital, ToulouseOTHER | 1 | Aug 19, 2015 | clinicaltrials |
| NCT01598454 | Use of Racotumomab in Patients With Pediatric Tumors Expressing N-glycolylated Gangliosides | completed | Phase 1 | 15 | Laboratorio Elea Phoenix S.A.INDUSTRY | 1 | Jul 29, 2015 | clinicaltrials |
| NCT01303835 | Low Dose Naltrexone for Glioma Patients | completed | Phase 2 | 110 | Katy PetersOTHER | 1 | Jul 17, 2015 | clinicaltrials |
| NCT02474966 | Effect of Deep TMS on the Permeability of the BBB in Patients With Glioblastoma Multiforme: a Pilot Study | completed | Phase 2 | 15 | University of Roma La SapienzaOTHER | 0 | Jun 18, 2015 | clinicaltrials |
| NCT01071837 | APG101 in Glioblastoma | completed | Phase 2 | 84 | Apogenix GmbHINDUSTRY | 2 | Jun 16, 2015 | clinicaltrials |
| NCT00112736 | Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma | completed | Phase 1 / Phase 2 | 69 | National Cancer Institute (NCI)NIH | 1 | Jun 15, 2015 | clinicaltrials |
| NCT00004146 | Carboxyamidotriazole + RT in Treating Patients Newly Diagnosed Supratentorial GBM | completed | Phase 2 | 55 | National Cancer Institute (NCI)NIH | 1 | May 8, 2015 | clinicaltrials |
| NCT00821080 | Vandetanib and Sirolimus in Patients With Recurrent Glioblastoma | completed | Phase 1 | 33 | Massachusetts General HospitalOTHER | 1 | May 1, 2015 | clinicaltrials |
| NCT00427440 | A Phase II Study to Treat Advanced Malignant Glioma | completed | Phase 2 | 61 | AmgenINDUSTRY | 0 | Apr 27, 2015 | clinicaltrials |
| NCT00968240 | Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) | completed | Phase 1 | 30 | Northwell HealthOTHER | 1 | Apr 22, 2015 | clinicaltrials |
| NCT01351337 | Functional Monitoring for Motor Pathway in Brain Tumor Surgery Within Eloquent Area | completed | N/A | 58 | Huashan HospitalOTHER | 1 | Apr 20, 2015 | clinicaltrials |
| NCT00049387 | Tipifarnib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma | completed | Phase 1 | 19 | National Cancer Institute (NCI)NIH | 1 | Apr 15, 2015 | clinicaltrials |
| NCT00979862 | Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma | completed | Phase 1 | 47 | National Cancer Institute (NCI)NIH | 1 | Apr 15, 2015 | clinicaltrials |
| NCT01604590 | Imaging Biomarkers of Tissue Microstructure and Vasculature as Predictors of Glioblastoma Multiforme | completed | — | 13 | Medical University of South CarolinaOTHER | 1 | Apr 13, 2015 | clinicaltrials |
| NCT00694837 | Study With Nelfinavir and Combined Radiochemotherapy for Glioblastoma | completed | Phase 1 | 6 | Maastricht Radiation OncologyOTHER | 1 | Apr 10, 2015 | clinicaltrials |
| NCT00943007 | Comparison of Standard Neuronavigation With Intraoperative Magnetic Resonance Imaging (MRI) for the Neurosurgical Treatment of Malignant Brain Tumors(RACING) | completed | N/A | 14 | Maastricht University Medical CenterOTHER | 2 | Apr 10, 2015 | clinicaltrials |
| NCT00996723 | Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) | completed | Phase 1 | 25 | St. Jude Children's Research HospitalOTHER | 1 | Apr 6, 2015 | clinicaltrials |
| NCT00004688 | Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms | completed | Phase 2 | 35 | Emory UniversityOTHER | 0 | Mar 25, 2015 | clinicaltrials |
| NCT01450449 | Short Course vs. Standard Course Radiotherapy in Elderly and/or Frail Patients With Glioblastoma Multiforme | completed | Phase 3 | 115 | International Atomic Energy AgencyOTHER_GOV | 14 | Mar 24, 2015 | clinicaltrials |
| NCT01417507 | Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone Surgery | completed | — | 82 | Radiation Therapy Oncology GroupNETWORK | 2 | Mar 18, 2015 | clinicaltrials |
| NCT01582516 | Safety Study of Replication-competent Adenovirus (Delta-24-rgd) in Patients With Recurrent Glioblastoma | completed | Phase 1 / Phase 2 | 20 | Erasmus Medical CenterOTHER | 1 | Mar 9, 2015 | clinicaltrials |
| NCT00179907 | A Phase I/II Study of the Photon Radiosurgery System | completed | Phase 1 / Phase 2 | 35 | Ann & Robert H Lurie Children's Hospital of ChicagoOTHER | 1 | Mar 2, 2015 | clinicaltrials |
| NCT00723827 | Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2) | completed | — | 682 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Jan 30, 2015 | clinicaltrials |
| NCT01386580 | An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma. | completed | Phase 1 / Phase 2 | 84 | BBB-Therapeutics B.V.INDUSTRY | 4 | Jan 22, 2015 | clinicaltrials |
| NCT00734682 | A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomas | completed | Phase 1 | 34 | University of California, San FranciscoOTHER | 1 | Jan 7, 2015 | clinicaltrials |
| NCT01131234 | Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors | completed | Phase 1 | 20 | National Cancer Institute (NCI)NIH | 1 | Dec 23, 2014 | clinicaltrials |
| NCT02227901 | Tipifarnib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | completed | Phase 1 | 19 | National Cancer Institute (NCI)NIH | 1 | Dec 23, 2014 | clinicaltrials |
| NCT01115491 | A Study of Bevacizumab and Extended Treatment of Temozolomide in Patients With Recurrent Glioblastoma Multiforme | completed | Phase 2 | 32 | Hoffmann-La RocheINDUSTRY | 1 | Dec 8, 2014 | clinicaltrials |
| NCT00213278 | Phase 2 Study of Vinblastine in Children With Recurrent or Refractory Low Grade Glioma | completed | Phase 2 | 50 | The Hospital for Sick ChildrenOTHER | 1 | Nov 20, 2014 | clinicaltrials |
| NCT00024570 | Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma | completed | Phase 1 / Phase 2 | 60 | INSYS Therapeutics IncINDUSTRY | 1 | Nov 14, 2014 | clinicaltrials |
| NCT00525525 | Study of Bevacizumab Plus Temodar and Tarceva in Patients With Glioblastoma or Gliosarcoma(AVF4120s) | completed | Phase 2 | 74 | University of California, San FranciscoOTHER | 1 | Nov 14, 2014 | clinicaltrials |
| NCT01158274 | RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors | completed | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 2 | Nov 7, 2014 | clinicaltrials |
| NCT00689221 | Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status(CENTRIC) | completed | Phase 3 | 545 | EMD SeronoINDUSTRY | 2 | Nov 4, 2014 | clinicaltrials |
| NCT00884416 | Sorafenib in Newly Diagnosed High Grade Glioma | completed | Phase 1 | 17 | University Hospital, GenevaOTHER | 1 | Nov 4, 2014 | clinicaltrials |
| NCT00576641 | Immunotherapy for Patients With Brain Stem Glioma and Glioblastoma | completed | Phase 1 | 22 | Cedars-Sinai Medical CenterOTHER | 1 | Oct 30, 2014 | clinicaltrials |
| NCT00411619 | Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex | completed | Phase 1 / Phase 2 | 28 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Oct 20, 2014 | clinicaltrials |
| NCT00528684 | Safety and Efficacy Study of REOLYSIN® in the Treatment of Recurrent Malignant Gliomas | completed | Phase 1 | 18 | Oncolytics BiotechINDUSTRY | 1 | Oct 2, 2014 | clinicaltrials |
Data updated 23 days agoSource updated Nov 5, 2015source: clinicaltrials