Subtype
Primary Central Nervous System Neoplasm
CI-CAN-00001432Explore in graph →
Non-malignant957 active trials5 approved drugs175 evidence items
- NCIt
- C102871
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Subtype
CI-CAN-00001432Explore in graph →
Clinical trials
3,294 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05941234 | Stem Cell Analysis, Omics (Including Immunomics) and Artificial Intelligence in Glioblastoma(IPerGlioGEM) | recruiting | N/A | 120 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT06054529 | Spatiotemporal Dimensions of Metabolism in Autochthonous Tumors of GBM Patients(GBM-FLUX2) | active not recruiting | — | 2 | AdventHealth Translational Research Institute |
| 1 |
| Mar 13, 2025 |
| clinicaltrials |
| NCT06781372 | Patient's Derived Organoids for Drug Screening in Glioblastoma(GlioPDO) | not yet recruiting | N/A | 100 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT06408428 | Glioma Intraoperative MicroElectroCorticoGraphy(MicroECoGG) | not yet recruiting | N/A | 50 | Institut National de la Santé Et de la Recherche Médicale, FranceOTHER_GOV | 1 | Mar 12, 2025 | clinicaltrials |
| NCT05274919 | Vascular Signature Mapping of Brain Tumor Genotypes(VASIM) | recruiting | — | 180 | Leiden University Medical CenterOTHER | 1 | Mar 10, 2025 | clinicaltrials |
| NCT05769660 | A Study to Evaluate Safety and Efficacy of BEY1107 in Combination with Temozolomide in Patients with Recurrent or Progressive Glioblastoma Multiforme (GBM) | recruiting | Phase 1 | 12 | BeyondBio Inc.INDUSTRY | 1 | Mar 10, 2025 | clinicaltrials |
| NCT05565326 | Response Assessment During MR-guided Radiation Therapy for Glioblastoma(MARGA) | recruiting | — | 20 | University of ZurichOTHER | 1 | Mar 3, 2025 | clinicaltrials |
| NCT03452579 | Nivolumab Plus Standard Dose Bevacizumab Versus Nivolumab Plus Low Dose Bevacizumab in GBM | active not recruiting | Phase 2 | 90 | David PeereboomOTHER | 1 | Feb 28, 2025 | clinicaltrials |
| NCT06853080 | Feasibility of Using Bortezomib With or Without Chemotherapy in Patients With Atypical Teratoid/Rhabdoid Tumors | active not recruiting | Phase 2 | 6 | Taipei Medical UniversityOTHER | 1 | Feb 28, 2025 | clinicaltrials |
| NCT04590664 | Verteporfin for the Treatment of Recurrent High Grade EGFR-Mutated Glioblastoma | recruiting | Phase 1 / Phase 2 | 24 | Emory UniversityOTHER | 1 | Feb 25, 2025 | clinicaltrials |
| NCT06845020 | CSF Proteomic Characterization of Glioblastomas | not yet recruiting | — | 15 | Univeridad Autonoma de GuadalajaraOTHER | 0 | Feb 25, 2025 | clinicaltrials |
| NCT05231655 | Ex VIvo DEtermiNed Cancer Therapy(EVIDENT) | recruiting | — | 600 | Sheffield Teaching Hospitals NHS Foundation TrustOTHER | 1 | Feb 24, 2025 | clinicaltrials |
| NCT06831773 | Clinical Study of Carbon Ion Radiotherapy for High-grade Glioma | recruiting | N/A | 23 | Gansu Wuwei Tumor HospitalOTHER | 1 | Feb 18, 2025 | clinicaltrials |
| NCT06832267 | Rituximab-Methotrexate-Temozolomide-Thiotepa (RMTT) Regimen As First-line Therapy for PCNS DLBCL | recruiting | N/A | 44 | Zhejiang Cancer HospitalOTHER | 1 | Feb 18, 2025 | clinicaltrials |
| NCT06832384 | Intensive Physiotherapy in Children Affected by Posterior Fossa Tumors | recruiting | — | 40 | IRCCS Eugenio MedeaOTHER | 1 | Feb 18, 2025 | clinicaltrials |
| NCT03181477 | Study Evaluating the Efficacy of Radiotherapy With SIB-IMRT, Associated With Temozolomide in Glioblastomas(Glio-SIB-Up) | active not recruiting | N/A | 67 | Centre Georges Francois LeclercOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT06000787 | MCT for the Harvard/UCSF ROBIN Center | recruiting | N/A | 47 | Brigham and Women's HospitalOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT06830356 | Somatostatin Receptor PET Imaging to Guide Radiotherapy Dose Escalation in High Risk Meningiomas.(SPIDER-MEN) | recruiting | N/A | 53 | Centro di Riferimento Oncologico - AvianoOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT06830421 | Adjusted High-dose Chemotherapy With Autologous Stem Cell Transplant vs. Conventional Immunochemotherapy in Elderly PCNSL Patients(PRIMA-CNS) | recruiting | Phase 3 | 340 | University Hospital FreiburgOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT04881032 | AGuIX Nanoparticles With Radiotherapy Plus Concomitant Temozolomide in the Treatment of Newly Diagnosed Glioblastoma(NANO-GBM) | active not recruiting | Phase 1 / Phase 2 | 66 | Centre Jean PerrinOTHER | 1 | Feb 13, 2025 | clinicaltrials |
| NCT06140875 | Amplitude Modulated Radiofrequency Electromagnetic Field Treatment Combined With Radiochemotherapy and Maintenance Chemotherapy in Patients With Glioblastoma (Brain-RF) | recruiting | N/A | 26 | Charite University, Berlin, GermanyOTHER | 1 | Feb 13, 2025 | clinicaltrials |
| NCT05473923 | PTCs-based Precision Treatment Strategy on Recurrent High-grade Gliomas | active not recruiting | Early Phase 1 | 30 | Beijing Tiantan HospitalOTHER | 1 | Feb 11, 2025 | clinicaltrials |
| NCT06814353 | Intraoperatively Observed Site of Origin and Growth Pattern of Medulloblastoma(ISOP) | enrolling by invitation | — | 100 | Christian DorferOTHER | 3 | Feb 7, 2025 | clinicaltrials |
| NCT06113705 | Imaging and Biological Markers for Prediction and Identification of Glioblastoma Pseudoprogression: a Prospective Study. | recruiting | N/A | 75 | Istituto Clinico HumanitasOTHER | 1 | Jan 31, 2025 | clinicaltrials |
| NCT03382158 | International PPB/DICER1 Registry | recruiting | — | 3,400 | Children's Hospitals and Clinics of MinnesotaOTHER | 1 | Jan 30, 2025 | clinicaltrials |
| NCT06801730 | Irinotecan Liposomes Combined With Bevacizumab in the Treatment of Recurrent Glioma(NALIRIBVRG) | recruiting | Phase 2 | 38 | Zhifeng Tian,MDOTHER | 1 | Jan 30, 2025 | clinicaltrials |
| NCT05911230 | Advanced Diffusion MRI to Differentiate Tumor Recurrence From Pseudoprogression in Patients With Glioblastoma and Brain Metastases(AiD-GLIO) | recruiting | N/A | 10 | University Hospital, Basel, SwitzerlandOTHER | 1 | Jan 29, 2025 | clinicaltrials |
| NCT06710249 | Impact of Salovum® and SPC® Flakes on Brain Tumor Induced Edema(AFBTEdema) | recruiting | Phase 2 | 20 | Peter SiesjöOTHER | 1 | Jan 27, 2025 | clinicaltrials |
| NCT05968053 | Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi)(DT-MiNi) | recruiting | — | 500 | Beijing Tiantan HospitalOTHER | 1 | Jan 23, 2025 | clinicaltrials |
| NCT06780592 | Vebreltinib Combined With Temozolomide for Glioblastoma (GBM) After Surgery | not yet recruiting | Phase 2 | 60 | Huashan HospitalOTHER | 0 | Jan 22, 2025 | clinicaltrials |
| NCT06787807 | Proteomic Analysis of Patients Undergoing Bariatric Surgery | not yet recruiting | N/A | 103 | Universidade Federal de PernambucoOTHER | 1 | Jan 22, 2025 | clinicaltrials |
| NCT06097975 | A Clinical Trial on Combined (Neo-)Adjuvant Intravenous Plus Intracranial Administration of Ipilimumab and Nivolumab in Recurrent Glioblastoma(NEO-GLITIPNI) | recruiting | Phase 1 | 18 | Universitair Ziekenhuis BrusselOTHER | 1 | Jan 20, 2025 | clinicaltrials |
| NCT06720727 | Craniospinal Irradiation in Histone AlteRed Midline Glioma(CHARM) | recruiting | N/A | 32 | Tata Memorial CentreOTHER | 1 | Jan 20, 2025 | clinicaltrials |
| NCT06782984 | Drug Response Testing and Repurposing Using Glioblastoma Organoid | recruiting | — | 150 | Chungnam National University HospitalOTHER | 1 | Jan 20, 2025 | clinicaltrials |
| NCT06703255 | A Phase 2 Study of HX301 in Patients with High-grade Giloma | recruiting | Phase 1 / Phase 2 | 72 | Hangzhou Hanx Biopharmaceuticals, Ltd.INDUSTRY | 1 | Jan 15, 2025 | clinicaltrials |
| NCT03709680 | Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors | active not recruiting | Phase 2 | 128 | PfizerINDUSTRY | 14 | Jan 14, 2025 | clinicaltrials |
| NCT06764537 | Evaluation of in Vitro Antitumor Activity of GD2 CAR-T Cells in Glioblastoma(BOOSTCAR) | not yet recruiting | N/A | 18 | Central Hospital, Nancy, FranceOTHER | 1 | Jan 8, 2025 | clinicaltrials |
| NCT06757153 | Safety and Efficacy of NRG-103 Injection in the Treatment of Recurrent Glioblastoma Patients | recruiting | Early Phase 1 | 15 | Zhongnan HospitalOTHER | 1 | Jan 3, 2025 | clinicaltrials |
| NCT06753617 | Cryoablation of Brain Neoplasm | enrolling by invitation | N/A | 20 | Erasmus Medical CenterOTHER | 1 | Dec 31, 2024 | clinicaltrials |
| NCT04758533 | Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy(AloCELYVIR) | active not recruiting | Phase 1 / Phase 2 | 13 | Hospital Infantil Universitario Niño Jesús, Madrid, SpainOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT06740097 | Feasibility of Aspirate Tissue Monitoring in Neuro-oncological Surgery(ATM GBM INT) | recruiting | N/A | 50 | Kuopio University HospitalOTHER | 2 | Dec 18, 2024 | clinicaltrials |
| NCT06740955 | Hypofractionated Radiotherapy | recruiting | N/A | 420 | The First Hospital of Jilin UniversityOTHER | 1 | Dec 18, 2024 | clinicaltrials |
| NCT06737146 | Study of MT027 in Patients with Recurrent or Progressive High-grade Glioma | not yet recruiting | Phase 1 | 12 | Suzhou Maximum Bio-tech Co., Ltd.INDUSTRY | 1 | Dec 17, 2024 | clinicaltrials |
| NCT06737250 | NB02 (Poseltinib) Combined Rituximab and Lenalidomide in R/R PCNSL(POTENTIAL-P) | recruiting | Phase 2 | 33 | NOBO MedicineINDUSTRY | 1 | Dec 17, 2024 | clinicaltrials |
| NCT06736470 | Surgical Suction Aspirates Fluorescence Measurement(ATM GBM) | recruiting | — | 25 | Kuopio University HospitalOTHER | 1 | Dec 16, 2024 | clinicaltrials |
| NCT06116903 | Clinical Relevance of Detecting Molecular Abnormalities in Glial Tumor Exosomes(ExoGLIE) | recruiting | N/A | 60 | University Hospital, LimogesOTHER | 1 | Dec 13, 2024 | clinicaltrials |
| NCT04195139 | Nivolumab and Temozolomide Versus Temozolomide Alone in Newly Diagnosed Elderly Patients With GBM(NUTMEG) | active not recruiting | Phase 2 | 103 | University of SydneyOTHER | 2 | Dec 11, 2024 | clinicaltrials |
| NCT05254197 | SeOuL cOhort of Brain Tumor MONitoring Study (SOLOMON)(SOLOMON) | recruiting | — | 3,000 | Seoul National University HospitalOTHER | 1 | Dec 3, 2024 | clinicaltrials |
| NCT06172595 | FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade Glioma(FET PET in HGG) | recruiting | Phase 2 | 22 | Singapore General HospitalOTHER | 1 | Dec 3, 2024 | clinicaltrials |
| NCT03395587 | Efficiency of Vaccination with Lysate-loaded Dendritic Cells in Patients with Newly Diagnosed Glioblastoma(GlioVax) | active not recruiting | Phase 2 | 136 | Heinrich-Heine University, DuesseldorfOTHER | 1 | Dec 2, 2024 | clinicaltrials |
Data updated 23 days agoSource updated Mar 13, 2025source: clinicaltrials