Cancer Family
Pleural Neoplasm
CI-CAN-00000323Explore in graph →
Non-malignant38 active trials4 approved drugs6 evidence items
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Cancer Family
CI-CAN-00000323Explore in graph →
Clinical trials
184 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01211275 | Standard Chemotherapy With of Without Axitinib in Malignant Mesothelioma(N08CPA) | completed | Phase 1 / Phase 2 | 32 | The Netherlands Cancer InstituteOTHER | 1 | Feb 28, 2017 | clinicaltrials |
| NCT01870609 | Placebo Controlled Study of VS-6063 in Subjects With Malignant Pleural Mesothelioma(COMMAND) | terminated | Phase 2 | 344 | Verastem, Inc.INDUSTRY | 15 | Jan 30, 2017 |
| NCT00571298 | Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma | completed | Phase 1 | 141 | Brigham and Women's HospitalOTHER | 1 | Jan 23, 2017 | clinicaltrials |
| NCT02639767 | Concurrent Pemetrexed/Cisplatin With Pleural Intensity Modulated Radiation Therapy for Patients With Unresectable Malignant Pleural Mesothelioma | withdrawn | Phase 1 | 0 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 7, 2016 | clinicaltrials |
| NCT02755675 | uPAR-PET for Prognostication in Patients With Non-small Cell Lung Cancer, Malignant Pleural Mesothelioma and Large Cell Neuroendocrine Carcinoma of the Lung | unknown | Phase 2 | 120 | Rigshospitalet, DenmarkOTHER | 1 | Nov 21, 2016 | clinicaltrials |
| NCT01861301 | Tivantinib in Treating Patients With Previously Treated Malignant Mesothelioma | terminated | Phase 2 | 18 | National Cancer Institute (NCI)NIH | 1 | Oct 24, 2016 | clinicaltrials |
| NCT00165503 | Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate | terminated | Phase 2 | 16 | Dana-Farber Cancer InstituteOTHER | 1 | Sep 9, 2016 | clinicaltrials |
| NCT01694654 | Epidemiology and Outcome of Solitary Fibrous Tumors of the Pleura. | unknown | — | 300 | University of ZurichOTHER | 1 | Apr 14, 2016 | clinicaltrials |
| NCT02588131 | A Study of Tremelimumab Combined With the Anti-PD-L1 MEDI4736 Antibody in Malignant Mesothelioma (NIBIT-MESO-1) | unknown | Phase 2 | 40 | Italian Network for Tumor Biotherapy FoundationOTHER | 1 | Oct 27, 2015 | clinicaltrials |
| NCT01212367 | Intrapleural Gene Transfer for Pleural Mesothelioma(IFN-alpha) | completed | Phase 1 | 13 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Sep 22, 2015 | clinicaltrials |
| NCT01769547 | A Phase II Study of Single-agent DOVitinib in Advanced Malignant PlEural Mesothelioma Which Has Progressed Following Prior Platinum-Antifolate Chemotherapy(DOVE-M) | terminated | Phase 2 | 12 | Ontario Clinical Oncology Group (OCOG)OTHER | 1 | Sep 17, 2015 | clinicaltrials |
| NCT00969098 | Response Evaluation in Malignant Pleural Mesothelioma | unknown | — | 150 | Istituto Clinico HumanitasOTHER | 1 | Aug 6, 2015 | clinicaltrials |
| NCT00747916 | Safety, Efficacy, and Side Effects Study of Interventional Cryotherapy in the Pleural Space("ICE PLS") | terminated | Phase 4 | 3 | CSA Medical, Inc.INDUSTRY | 1 | Jul 16, 2015 | clinicaltrials |
| NCT02497053 | Four Versus Six Cycles of Pemetrexed/Platinum for MPM | unknown | Phase 2 | 70 | Ain Shams UniversityOTHER | 1 | Jul 14, 2015 | clinicaltrials |
| NCT01024946 | Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity | completed | Phase 2 | 11 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 12, 2015 | clinicaltrials |
| NCT00867711 | Molecular Predictors of Pemetrexed and Carboplatin Response in Malignant Pleural Mesothelioma (MPM) Patients | completed | — | 121 | Istituto Clinico HumanitasOTHER | 1 | Dec 2, 2014 | clinicaltrials |
| NCT01279967 | A Clinical Trial of ADI-PEG 20TM in Patients With Malignant Pleural Mesothelioma(ADAM) | unknown | Phase 2 | 70 | Barts & The London NHS TrustOTHER | 1 | Nov 20, 2014 | clinicaltrials |
| NCT00309946 | Cediranib Maleate in Treating Patients With Malignant Mesothelioma That Cannot Be Removed By Surgery | completed | Phase 2 | 51 | National Cancer Institute (NCI)NIH | 1 | Jul 31, 2014 | clinicaltrials |
| NCT00165516 | Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfate | completed | Phase 2 | 85 | Dana-Farber Cancer InstituteOTHER | 1 | Mar 27, 2014 | clinicaltrials |
| NCT00165555 | Pleurectomy/Decortication Followed by Intrathoracic/Intraperitoneal Heated Cisplatin for Malignant Pleural Mesothelioma | completed | Phase 1 | 70 | Dana-Farber Cancer InstituteOTHER | 1 | Mar 27, 2014 | clinicaltrials |
| NCT01241682 | Dendritic Cell-based Immunotherapy Combined With Low-dose Cyclophosphamide in Patients With Malignant Mesothelioma(PMR-MM-002) | completed | Phase 1 | 10 | Erasmus Medical CenterOTHER | 1 | Feb 27, 2014 | clinicaltrials |
| NCT00027703 | Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 106 | National Cancer Institute (NCI)NIH | 1 | Feb 11, 2014 | clinicaltrials |
| NCT01105390 | AMG 102, Pemetrexed Disodium, and Cisplatin in Treating Patients With Malignant Pleural Mesothelioma | withdrawn | Phase 2 | 0 | National Cancer Institute (NCI)NIH | 0 | Aug 2, 2013 | clinicaltrials |
| NCT00107432 | Sorafenib Tosylate in Treating Patients With Malignant Mesothelioma. | completed | Phase 2 | 44 | National Cancer Institute (NCI)NIH | 1 | Jun 5, 2013 | clinicaltrials |
| NCT00039182 | Erlotinib in Treating Patients With Malignant Mesothelioma of the Lung | completed | Phase 2 | 55 | National Cancer Institute (NCI)NIH | 1 | Jan 24, 2013 | clinicaltrials |
| NCT00025207 | Gefitinib in Treating Patients With Malignant Mesothelioma | completed | Phase 2 | 40 | National Cancer Institute (NCI)NIH | 1 | Jan 17, 2013 | clinicaltrials |
| NCT01353482 | A Phase I/II Study of First Line Vorinostat With Pemetrexed-cisplatin, in Patients With Malignant Pleural Mesothelioma(MESO-02) | withdrawn | Phase 1 / Phase 2 | 0 | University College, LondonOTHER | 0 | Mar 22, 2012 | clinicaltrials |
| NCT01343264 | Trimodality Therapy for Malignant Pleural Mesothelioma | unknown | — | 200 | HSK WiesbadenOTHER | 1 | Apr 28, 2011 | clinicaltrials |
| NCT01243632 | Gemcitabine in Long Infusion and Cisplatin for Malignant Pleural Mesothelioma Treatment | completed | Phase 2 | 78 | Institute of Oncology LjubljanaOTHER | 1 | Nov 18, 2010 | clinicaltrials |
| NCT00280982 | Dendritic Cell-based Immunotherapy in Mesothelioma | completed | Phase 1 | 10 | Erasmus Medical CenterOTHER | 1 | Nov 16, 2010 | clinicaltrials |
| NCT00272558 | Study of Carboplatin and Vinorelbine in Malignant Pleural Mesothelioma | completed | Phase 2 | 40 | Rigshospitalet, DenmarkOTHER | 1 | Sep 18, 2009 | clinicaltrials |
| NCT00087698 | Phase II Trial of Neo-Adjuvant Pemetrexed Plus Cisplatin Followed by Surgery and Radiation for Pleural Mesothelioma | completed | Phase 2 | 77 | Eli Lilly and CompanyINDUSTRY | 1 | May 12, 2009 | clinicaltrials |
| NCT00886028 | Palliative Treatment With Liposomal Doxorubicin Plus Cisplatin for Patients With Malignant Pleural Mesothelioma | unknown | Phase 2 | 31 | National Institute of CancerologíaOTHER_GOV | 1 | Apr 22, 2009 | clinicaltrials |
| NCT00386815 | Safety Confirmation Study of Pemetrexed Plus Cisplatin in Patients With Malignant Pleural Mesothelioma | completed | Phase 2 | 20 | Eli Lilly and CompanyINDUSTRY | 1 | Apr 11, 2007 | clinicaltrials |
Data updated 22 days agoSource updated Feb 28, 2017source: clinicaltrials