Cancer
Neoplasm of Uncertain Histogenesis
CI-CAN-00000034Explore in graph →
Non-malignant20,280 active trials259 approved drugs3,813 evidence items
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Cancer
CI-CAN-00000034Explore in graph →
Clinical trials
91,351 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05333874 | CIPHER Study: Pilot Study to Study the Role of ctDNA in Triple Negative and HER2 Positive Early Stage | active not recruiting | Early Phase 1 | 34 | Rutgers, The State University of New JerseyOTHER | 1 | Feb 9, 2026 | clinicaltrials |
| NCT02724202 | Curcumin in Combination With 5FU for Colon Cancer | terminated | Early Phase 1 | 15 | Baylor Research InstituteOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT03543969 | Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma | active not recruiting | Early Phase 1 | 14 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT05093335 | In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET | recruiting | Early Phase 1 | 30 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT05316116 | Siltuximab in Large Granular Lymphocytic Leukemia (LGLL) | terminated | Early Phase 1 | 6 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT05620342 | Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer | recruiting | Early Phase 1 | 24 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT07236177 | B-GLUCANCER2 : A Pilot Study Evaluating a New Method for Cancer Detection by Measuring the Activity of Different Glycosidase Enzymes in the Plasma of Patients With a Localized Cancer.(B-GLUCANCER2) | recruiting | Early Phase 1 | 220 | Poitiers University HospitalOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT04457089 | Statin Therapy to Reduce Progression in Women With Platinum Sensitive Ovarian Cancer | completed | Early Phase 1 | 18 | Marc GoodmanOTHER | 1 | Feb 4, 2026 | clinicaltrials |
| NCT05800405 | Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma | recruiting | Early Phase 1 | 9 | City of Hope Medical CenterOTHER | 1 | Feb 4, 2026 | clinicaltrials |
| NCT06408298 | HCQ in Resectable Localized Prostate Cancer | recruiting | Early Phase 1 | 20 | Lionel.D.Lewis, MDOTHER | 1 | Feb 4, 2026 | clinicaltrials |
| NCT04044872 | Hyperpolarized Carbon 13-Based Metabolic Imaging to Detect Radiation-Induced Cardiotoxicity | terminated | Early Phase 1 | 3 | University of Texas Southwestern Medical CenterOTHER | 1 | Feb 2, 2026 | clinicaltrials |
| NCT07381582 | Safety, Tolerability and Preliminary Efficacy of 161Tb-LNC1011 (PSMA Radioligand) in Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)(161Tb-LNC1011) | not yet recruiting | Early Phase 1 | 15 | Peking Union Medical College HospitalOTHER | 1 | Feb 2, 2026 | clinicaltrials |
| NCT06639191 | [177Lu]Lu-AKIR001 First-in-human Study(AKIR001) | recruiting | Early Phase 1 | 15 | Karolinska University HospitalOTHER | 1 | Jan 30, 2026 | clinicaltrials |
| NCT01881048 | Window of Opportunity Study Targeting the Inflammatory Milieu | completed | Early Phase 1 | 42 | University of Colorado, DenverOTHER | 1 | Jan 29, 2026 | clinicaltrials |
| NCT07371247 | Based on ctDNA-MRD Guided Adjuvant Treatment Escalation After Definitive Chemoradiotherapy for Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma: a Study on Safety and Efficacy | enrolling by invitation | Early Phase 1 | 65 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Jan 27, 2026 | clinicaltrials |
| NCT03321045 | Positron Emission Tomography (PET) Imaging With Zirconium-89 (89Zr)-Trastuzumab for Prediction of HER2 Targeted Therapy Effectiveness | recruiting | Early Phase 1 | 10 | University of Alabama at BirminghamOTHER | 1 | Jan 26, 2026 | clinicaltrials |
| NCT05553782 | Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers | recruiting | Early Phase 1 | 30 | Brigham and Women's HospitalOTHER | 1 | Jan 26, 2026 | clinicaltrials |
| NCT05921253 | Neuromodulation of Cardiovascular Risks Associated With Cardiotoxic Chemotherapy(OU-SCC-NCAN) | recruiting | Early Phase 1 | 104 | University of OklahomaOTHER | 1 | Jan 26, 2026 | clinicaltrials |
| NCT04825275 | Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trial | terminated | Early Phase 1 | 7 | Milton S. Hershey Medical CenterOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT06499090 | Mirtazapine for Acute and Chronic Post Mastectomy Pain | completed | Early Phase 1 | 62 | Assiut UniversityOTHER | 1 | Jan 22, 2026 | clinicaltrials |
| NCT06922825 | Pilot Study Evaluating Tumor Microenvironment Interaction in Solid Tumor Patients | withdrawn | Early Phase 1 | 0 | Eben RosenthalOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT07242417 | TC-G203 for Patients With GPC3-Positive Advanced Solid Tumors | recruiting | Early Phase 1 | 30 | Beijing GoBroad HospitalOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT07356466 | Clinical Efficacy of Pucotenlimab Combined With Lenvatinib and SOX Versus SOX Alone in Patients With HER2-Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma(FUGES032) | enrolling by invitation | Early Phase 1 | 100 | Fujian Medical UniversityOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT07185490 | IASO104 for the Treatment of Patients With Relapsed/Refractory Multiple Myeloma(IASO104) | not yet recruiting | Early Phase 1 | 40 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 0 | Jan 20, 2026 | clinicaltrials |
| NCT07352345 | Head to Head, Prospective, Open Label Multicenter Study on the Diagnostic Efficacy of GPC3 Targeted PET Imaging and Enhanced Magnetic Resonance Imaging for Hepatocellular Carcinoma | not yet recruiting | Early Phase 1 | 150 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT01269593 | PET Imaging of Cancer Patients Using 124I-PUH71: A Pilot Study | active not recruiting | Early Phase 1 | 63 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jan 15, 2026 | clinicaltrials |
| NCT06220214 | Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer | recruiting | Early Phase 1 | 30 | Alison StopeckOTHER | 1 | Jan 15, 2026 | clinicaltrials |
| NCT07343791 | Efficacy and Safety Study of DC-CIK Cell Therapy Combined With Epaloliposide, Vortexil, and Regorafenib as Third-line Treatment for Advanced Colorectal Cancer. | recruiting | Early Phase 1 | 14 | JIANG LONGWEIOTHER | 1 | Jan 15, 2026 | clinicaltrials |
| NCT06579248 | Intraoral Hypothermia Device for Preserving Taste During Radiation | recruiting | Early Phase 1 | 15 | Henry Ford Health SystemOTHER | 1 | Jan 14, 2026 | clinicaltrials |
| NCT07340424 | A Prospective, Open-label, Single-arm, Exploratory Clinical Trial to Evaluate the Safety and Tolerability of 225Ac-TR2205 Injection in Patients With Triple-negative Breast Cancer. | recruiting | Early Phase 1 | 15 | Xiaorong SunOTHER | 1 | Jan 14, 2026 | clinicaltrials |
| NCT07341360 | Pseudovax - A Cancer Vaccine for Patients With Pseudomyxoma Peritonei(Pseudovax) | recruiting | Early Phase 1 | 10 | Oslo University HospitalOTHER | 1 | Jan 14, 2026 | clinicaltrials |
| NCT06928922 | Inhaled mRNA Tumor-associated Antigen Dry Powder Vaccine in Advanced Lung Cancer and Lung Metastasis of Solid Tumors. | recruiting | Early Phase 1 | 83 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Jan 13, 2026 | clinicaltrials |
| NCT07336823 | JY232(JY232) Injection in Relapsed/Refractory Multiple Myeloma | recruiting | Early Phase 1 | 9 | Shenzhen Genocury Biotech Co., Ltd.INDUSTRY | 1 | Jan 13, 2026 | clinicaltrials |
| NCT07335094 | A Clinical Study of Humanized CD19 CAR-T Cells With TLR2 for the Treatment of Adult Patients With Naive B-Cell Acute Lymphoblastic Leukemia/Lymphoma Who Are Intolerant to Intensive Chemotherapy | not yet recruiting | Early Phase 1 | 60 | Zhujiang HospitalOTHER | 0 | Jan 12, 2026 | clinicaltrials |
| NCT07328087 | COLONYVAQ™, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer(COLONYVAQ™-CRC) | recruiting | Early Phase 1 | 12 | Biogenea Pharmaceuticals Ltd.INDUSTRY | 1 | Jan 9, 2026 | clinicaltrials |
| NCT04514029 | Neurotoxicity Prophylaxis With Intrathecal Dexamethasone and Simvastatin Post Axi-Cel | active not recruiting | Early Phase 1 | 37 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT04869449 | Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas | terminated | Early Phase 1 | 1 | Milton S. Hershey Medical CenterOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT04897763 | Assessment of Safety, Tolerability, Radiation Dosimetry, Imaging Properties of 89Zr-girentuximab in Patients With NMIBC(PERTINENCE) | completed | Early Phase 1 | 6 | Institut Cancerologie de l'OuestOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT07316361 | GYNORYLAQ™-VLINIVAL™: Ψ-Guided Personalized Neoantigen Peptide Vaccine for High-Risk Endometrial Cancer(GYNORYLAQ™) | enrolling by invitation | Early Phase 1 | 40 | Biogenea Pharmaceuticals Ltd.INDUSTRY | 1 | Jan 7, 2026 | clinicaltrials |
| NCT07322159 | IASO206 in Patients With Relapsed/Refractory Multiple Myeloma | not yet recruiting | Early Phase 1 | 12 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 0 | Jan 7, 2026 | clinicaltrials |
| NCT05336266 | A Feasibility Study of Ketorolac Treatment for Cachexia in Patients With Advanced Pancreatic Ductal Adenocarcinoma(KetoROCX) | active not recruiting | Early Phase 1 | 28 | Andrew Hendifar, MDOTHER | 1 | Jan 6, 2026 | clinicaltrials |
| NCT06514768 | JY231 (JY231) Injection for the Treatment of B-cell Acute Lymphoblastic Leukemia (B-ALL) | recruiting | Early Phase 1 | 20 | 920th Hospital of Joint Logistics Support Force of People's Liberation Army of ChinaOTHER | 1 | Jan 6, 2026 | clinicaltrials |
| NCT04370483 | Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma | active not recruiting | Early Phase 1 | 1 | City of Hope Medical CenterOTHER | 1 | Jan 5, 2026 | clinicaltrials |
| NCT05560399 | A Study of Iberdomide (CC-220) in Combination With Elotuzumab and Dexamethasone for Relapsed/Refractory Multiple Myeloma(CC-220) | active not recruiting | Early Phase 1 | 7 | Icahn School of Medicine at Mount SinaiOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT05868486 | Analysis of Whole Body Magnetic Resonance Imaging and Liquid Biopsy for Early Detection of Cancer in Patients With a Strong Family History of Cancer | active not recruiting | Early Phase 1 | 100 | City of Hope Medical CenterOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT06829173 | Concurrent XRD-0394 With Radiation Therapy for High Grade Gliomas | recruiting | Early Phase 1 | 39 | NYU Langone HealthOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT07312630 | Clinical Study of LV009 Injection for the Treatment of Relapsed/Refractory CD19-Positive Hematologic and Lymphoid Malignancies | recruiting | Early Phase 1 | 19 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 1 | Dec 31, 2025 | clinicaltrials |
| NCT06645808 | PET-imaging of Two Vartumabs in Patients With Solid Tumors(VARTUTRACE) | recruiting | Early Phase 1 | 32 | Var2 PharmaceuticalsINDUSTRY | 1 | Dec 29, 2025 | clinicaltrials |
| NCT02304978 | Prognostic Value of Tissue Factor (TF) in Blood t in Colorectal Cancer in Adults(TF) | completed | Early Phase 1 | 26 | University Hospital, LilleOTHER | 1 | Dec 26, 2025 | clinicaltrials |
| NCT05183048 | Comparison of 89Zr Panitumumab and (18)F-Fluorodeoxyglucose to Identify Head and Neck Squamous Cell Carcinoma | recruiting | Early Phase 1 | 14 | University of Alabama at BirminghamOTHER | 1 | Dec 26, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Feb 9, 2026source: clinicaltrials