Cancer Family
Melanocytic Neoplasm
CI-CAN-00000026Explore in graph →
Non-malignant610 active trials13 approved drugs233 evidence items
- NCIt
- C7058
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Cancer Family
CI-CAN-00000026Explore in graph →
Clinical trials
3,258 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06054555 | A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma | active not recruiting | Phase 3 | 633 | AmgenINDUSTRY | 31 | Jan 12, 2026 | clinicaltrials |
| NCT06887348 | A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3(RPx) | recruiting | — | 50 | Replimune, Inc.INDUSTRY | 2 | Jan 12, 2026 | clinicaltrials |
| NCT03873818 | Low Dose Ipilimumab With Pembrolizumab in Treating Patients With Melanoma That Has Spread to the Brain | completed | Phase 2 | 24 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 9, 2026 | clinicaltrials |
| NCT05002569 | A Study to Assess Adjuvant Immunotherapy With Nivolumab Plus Relatlimab Versus Nivolumab Alone After Complete Resection of Stage III-IV Melanoma(RELATIVITY-098) | terminated | Phase 3 | 1,093 | Bristol-Myers SquibbINDUSTRY | 25 | Jan 8, 2026 | clinicaltrials |
| NCT05902520 | Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors(ACT) | active not recruiting | Phase 1 | 18 | AgonOx, Inc.INDUSTRY | 1 | Jan 8, 2026 | clinicaltrials |
| NCT06063746 | Compassionate Use of Vidutolimod | no longer available | — | — | Regeneron PharmaceuticalsINDUSTRY | 0 | Jan 8, 2026 | clinicaltrials |
| NCT06946225 | ACTengine® IMA203 Combined With mRNA-4203 | recruiting | Phase 1 | 15 | Immatics US, Inc.INDUSTRY | 1 | Jan 8, 2026 | clinicaltrials |
| NCT07161310 | Urolithin A in Patients With Previously Untreated Solid Tumors Receiving Immune Checkpoint Inhibitors(MitoCancer) | recruiting | N/A | 45 | Goethe UniversityOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT01004952 | Measuring Real Time Decision-Making About Ultraviolet Radiation (UVR) Protection | completed | — | 94 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT03746431 | A Phase 1 Study of [225Ac]-FPI-1434 Injection | terminated | Phase 1 | 78 | Fusion Pharmaceuticals Inc.INDUSTRY | 3 | Jan 7, 2026 | clinicaltrials |
| NCT05707286 | Pilot Study to Determine Pro-Inflammatory Cytokine Kinetics During Immune Checkpoint Inhibitor Therapy(ICI-PICK) | completed | — | 98 | Indiana UniversityOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT05544929 | A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers | active not recruiting | Phase 1 | 126 | Novartis PharmaceuticalsINDUSTRY | 12 | Jan 6, 2026 | clinicaltrials |
| NCT07320222 | CARE-Melanoma Trial(CARE-Melanoma) | not yet recruiting | Phase 1 | 30 | McMaster UniversityOTHER | 0 | Jan 6, 2026 | clinicaltrials |
| NCT03929029 | Neoantigen Vaccine Plus Locally Administered Ipilimumab and Systemic Nivolumab in Advanced Melanoma | active not recruiting | Phase 1 | 11 | Dana-Farber Cancer InstituteOTHER | 1 | Jan 5, 2026 | clinicaltrials |
| NCT05428007 | Interleukin-6 Receptor Inhibitor Sarilumab in Combination With Ipilimumab, Nivolumab and Relatlimab in Patients With Unresectable Stage III or Stage IV Melanoma | recruiting | Phase 2 | 105 | NYU Langone HealthOTHER | 1 | Jan 5, 2026 | clinicaltrials |
| NCT04129515 | NovoTTF-200A + Pembrolizumab In Melanoma Brain Metastasis | withdrawn | Phase 1 / Phase 2 | 0 | Brown UniversityOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT01266096 | PET Imaging of Patients With Melanoma and Malignant Brain Tumors Using an 124I-labeled cRGDY Silica Nanomolecular Particle Tracer: A Microdosing Study | active not recruiting | N/A | 10 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 31, 2025 | clinicaltrials |
| NCT05307289 | Study of Alterations in Tumor Metabolism Associated With the Development of Immunotherapy Resistance in Melanoma(MEL-META) | recruiting | N/A | 20 | Centre Hospitalier Universitaire de NiceOTHER | 1 | Dec 31, 2025 | clinicaltrials |
| NCT02917473 | Comparison of Two Strategies for Counseling Skin Examination and Sun Protection in First-degree Relatives of Patients With Melanoma(FADEMELA) | completed | N/A | 420 | University Hospital, ToursOTHER | 1 | Dec 30, 2025 | clinicaltrials |
| NCT04490564 | Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood and Primary Tumor in HNSCC/NSCLC/Melanoma | completed | — | 135 | Pharmassist LtdINDUSTRY | 1 | Dec 30, 2025 | clinicaltrials |
| NCT07310758 | Contrast-enhanced Ultrasound for Sentinel Node Detection | recruiting | Phase 2 / Phase 3 | 91 | The Netherlands Cancer InstituteOTHER | 1 | Dec 30, 2025 | clinicaltrials |
| NCT01970358 | A Phase I Study With a Personalized NeoAntigen Cancer Vaccine in Melanoma | completed | Phase 1 | 15 | Patrick Ott, MD, PhDOTHER | 1 | Dec 29, 2025 | clinicaltrials |
| NCT06022029 | A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.(ON-5001) | recruiting | Phase 1 | 168 | OncoNano Medicine, Inc.INDUSTRY | 2 | Dec 24, 2025 | clinicaltrials |
| NCT06626256 | STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma | withdrawn | Phase 1 | 0 | City of Hope Medical CenterOTHER | 0 | Dec 24, 2025 | clinicaltrials |
| NCT07302607 | Predictive Factors of Complete Response to Immunotherapy in Metastatic Melanoma: a Single-center Retrospective Study Between 2013 and 2021(IMM) | recruiting | — | 221 | University Hospital, Strasbourg, FranceOTHER | 1 | Dec 24, 2025 | clinicaltrials |
| NCT03161431 | SX-682 Treatment in Subjects With Metastatic Melanoma Concurrently Treated With Pembrolizumab | active not recruiting | Phase 1 | 77 | Syntrix Biosystems, Inc.INDUSTRY | 1 | Dec 23, 2025 | clinicaltrials |
| NCT04889118 | Safety and Efficacy Study of Pembrolizumab (MK-3475) Combined With Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Advanced Melanoma (MK-7902-003/E7080-G000-312/LEAP-003)-China Extension Study | completed | Phase 3 | 131 | Merck Sharp & Dohme LLCINDUSTRY | 1 | Dec 23, 2025 | clinicaltrials |
| NCT06120712 | A Study of GC101 TIL in Advanced Melanoma (BZ)(MIZAR-002) | completed | Phase 1 / Phase 2 | 18 | Shanghai Juncell TherapeuticsINDUSTRY | 1 | Dec 23, 2025 | clinicaltrials |
| NCT01005745 | Lymphodepletion Plus Adoptive Cell Transfer With High Dose IL-2 in Patients With Metastatic Melanoma | completed | N/A | 19 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Dec 19, 2025 | clinicaltrials |
| NCT01701674 | Ipilimumab With Lymphodepletion Plus Adoptive Cell Transfer and High Dose IL-2 in Melanoma Mets Pts | completed | N/A | 13 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Dec 19, 2025 | clinicaltrials |
| NCT03509467 | Using MC1R Genotype to Impact Melanoma Risk Behavior | completed | N/A | 2,054 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 2 | Dec 19, 2025 | clinicaltrials |
| NCT04079166 | SCIB1 and iSCIB1+ in Melanoma Patients Receiving Nivolumab With Ipilimumab or SCIB1 With Pembrolizumab (The SCOPE Study) | active not recruiting | Phase 2 | 173 | Scancell LtdINDUSTRY | 1 | Dec 19, 2025 | clinicaltrials |
| NCT06994208 | Characteristics of Adult Patients With Melanoma Diagnosis <40 Years Age.(MELA_2025) | recruiting | — | 25 | Ente Ospedaliero Ospedali GallieraOTHER | 1 | Dec 19, 2025 | clinicaltrials |
| NCT07293598 | Investigation of the ROle of faT and inflAmmaTory Cells in mElanoma(ROTATE) | not yet recruiting | — | 20 | The Christie NHS Foundation TrustOTHER | 1 | Dec 19, 2025 | clinicaltrials |
| NCT04489433 | Compassionate Use Program to Access Trametinib and Dabrafenib for Patients With BRAF Mutation-positive Metastatic Melanoma | no longer available | — | — | Novartis PharmaceuticalsINDUSTRY | 0 | Dec 18, 2025 | clinicaltrials |
| NCT06590480 | An Expanded Access Program for VO (RP1) in Combination With Nivolumab in Patients With Advanced Melanoma(RPL-EAP-001) | no longer available | — | — | Replimune, Inc.INDUSTRY | 0 | Dec 18, 2025 | clinicaltrials |
| NCT07251335 | Melanoma of the Skin and Exposure to Solar Ultraviolet Radiation at Work in Modena Territory: a Case-control Study to Promote an Active Search and Prevention of Occupational Diseases Based on Recent INAIL Criteria(Mesur) | recruiting | — | 300 | University of Modena and Reggio EmiliaOTHER | 1 | Dec 18, 2025 | clinicaltrials |
| NCT03567889 | Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients(NeoDREAM) | recruiting | Phase 3 | 186 | Philogen S.p.A.INDUSTRY | 3 | Dec 17, 2025 | clinicaltrials |
| NCT04082962 | Dexamethasone Implant for Retinal Detachment in Uveal Melanoma | completed | Phase 1 | 10 | Ivana K. KimOTHER | 1 | Dec 17, 2025 | clinicaltrials |
| NCT04688658 | Duvelisib in Combination With Nivolumab in Patients With Advanced Unresectable Melanoma | terminated | Phase 1 / Phase 2 | 13 | John KirkwoodOTHER | 1 | Dec 17, 2025 | clinicaltrials |
| NCT07256184 | Prognostic and Treatment-Response Factors in Metastatic Melanoma: Multi-Center Analysis(MEL-CARE) | completed | — | 232 | Ankara Etlik City HospitalOTHER_GOV | 1 | Dec 15, 2025 | clinicaltrials |
| NCT04961619 | Adjuvant Dabrafenib and Trametinib Treatment in Patients With Completely Resected High-risk Stage III Melanoma.(LEAD Melanoma) | completed | — | 39 | Novartis PharmaceuticalsINDUSTRY | 1 | Dec 12, 2025 | clinicaltrials |
| NCT06794775 | SWE-NEO: Swedish NeoAdjuvant Trial Comparing Monotherapy to Combined Immunotherapy in Resectable Stage III Melanoma(SWE-NEO) | recruiting | Phase 3 | 128 | Hildur HelgadottirOTHER | 1 | Dec 12, 2025 | clinicaltrials |
| NCT01950390 | Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery | completed | Phase 2 | 169 | National Cancer Institute (NCI)NIH | 1 | Dec 11, 2025 | clinicaltrials |
| NCT04157985 | Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors | completed | Phase 3 | 161 | Dan ZandbergOTHER | 1 | Dec 11, 2025 | clinicaltrials |
| NCT05098184 | A Study of GC101 TIL in Advanced Melanoma (10hospital) | recruiting | Early Phase 1 | 50 | Shanghai Juncell TherapeuticsINDUSTRY | 1 | Dec 11, 2025 | clinicaltrials |
| NCT07277920 | Reflectance Confocal Microscopy and Molecular Correlation in Atypical Melanocytic Lesions | recruiting | — | 200 | University of Modena and Reggio EmiliaOTHER | 1 | Dec 11, 2025 | clinicaltrials |
| NCT02374242 | Anti-PD 1 Brain Collaboration for Patients With Melanoma Brain Metastases(ABC) | active not recruiting | Phase 2 | 76 | Melanoma Institute AustraliaOTHER | 1 | Dec 10, 2025 | clinicaltrials |
Data updated 24 days agoSource updated Jan 12, 2026source: clinicaltrials