Hematologic Malignancy
Mature B-Cell Neoplasm
CI-CAN-00003258Explore in graph →
HematologicNon-malignant1,787 active trials44 approved drugs119 evidence items
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Hematologic Malignancy
CI-CAN-00003258Explore in graph →
Genomics
20 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
263 cases with simple somatic mutation data · 324 cases total · Data Release 46.0 · mapped to Burkitt Lymphoma ONTOLOGY_EXACT
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| SHCBP1 |
| Ssm |
| 73 |
| 263 |
| 27.8% |
| gdc |
| 2 | VPS35 | Ssm | 67 | 263 | 25.5% | gdc |
| 3 | ORC6 | Ssm | 66 | 263 | 25.1% | gdc |
| 4 | TPTE | Ssm | 66 | 263 | 25.1% | gdc |
| 5 | MYLK3 | Ssm | 62 | 263 | 23.6% | gdc |
| 6 | IGLL5 | Ssm | 60 | 263 | 22.8% | gdc |
| 7 | C16orf87 | Ssm | 56 | 263 | 21.3% | gdc |
| 8 | PTPRC | Ssm | 50 | 263 | 19% | gdc |
| 9 | ZNF280B | Ssm | 48 | 263 | 18.3% | gdc |
| 10 | ZNF280A | Ssm | 47 | 263 | 17.9% | gdc |
| 12 | PRAME | Ssm | 46 | 263 | 17.5% | gdc |
| 11 | GGTLC2 | Ssm | 46 | 263 | 17.5% | gdc |
| 13 | MYC | Ssm | 45 | 263 | 17.1% | gdc |
| 14 | OR11H12 | Ssm | 44 | 263 | 16.7% | gdc |
| 15 | ATP6V1G3 | Ssm | 43 | 263 | 16.3% | gdc |
| 16 | SLAMF6 | Ssm | 43 | 263 | 16.3% | gdc |
| 18 | CD84 | Ssm | 40 | 263 | 15.2% | gdc |
| 17 | ENSA | Ssm | 40 | 263 | 15.2% | gdc |
| 22 | ADAMTSL4 | Ssm | 39 | 263 | 14.8% | gdc |
| 20 | MLLT11 | Ssm | 39 | 263 | 14.8% | gdc |
| 23 | GABPB2 | Ssm | 39 | 263 | 14.8% | gdc |
| 26 | C1orf56 | Ssm | 39 | 263 | 14.8% | gdc |
| 19 | GOLPH3L | Ssm | 39 | 263 | 14.8% | gdc |
| 24 | TARS2 | Ssm | 39 | 263 | 14.8% | gdc |
| 25 | CD48 | Ssm | 39 | 263 | 14.8% | gdc |
| 21 | CDC42SE1 | Ssm | 39 | 263 | 14.8% | gdc |
| 29 | ECM1 | Ssm | 38 | 263 | 14.4% | gdc |
| 36 | KCNE1B | Ssm | 38 | 263 | 14.4% | gdc |
| 35 | HORMAD1 | Ssm | 38 | 263 | 14.4% | gdc |
| 42 | SMIM34B | Ssm | 38 | 263 | 14.4% | gdc |
Data updated 22 days agoSource updated Data Release 46.0