Subtype
Malignant Retroperitoneal Neoplasm
CI-CAN-00001174Explore in graph →
41 active trials1 approved drugs2 evidence items
- NCIt
- C3537
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Subtype
CI-CAN-00001174Explore in graph →
Clinical trials
132 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (17)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07141147 | A Prospective, Randomized, Multicenter Clinical Study Comparing Adjuvant Radiotherapy Versus Observation in High-risk Localized Adrenocortical Carcinoma After Surgery. | not yet recruiting | N/A | 58 | Sun Yat-sen UniversityOTHER | 1 | Sep 3, 2025 | clinicaltrials |
| NCT06634706 | SCINTIX [BgRT} Using RMRS in Solid and Soft Tissue Tumors | not yet recruiting | N/A | 96 | RefleXion MedicalINDUSTRY | 0 | Aug 13, 2025 | clinicaltrials |
| NCT05634577 | A Phase II Study to Evaluate the Efficacy and Safety of Pembrolizumab in Combination With Mitotane in Patients With Advanced Adrenocortical Carcinoma | terminated | Phase 2 | 3 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 19, 2025 | clinicaltrials |
| NCT06831175 | Phase II Study of PD-1 Inhibitor Combined With Apatinib and Mitotane in the Treatment of Advanced Adrenal Cortical Carcinoma | recruiting | Phase 2 | 28 | West China HospitalOTHER | 1 | Jun 3, 2025 | clinicaltrials |
| NCT03508570 | Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal Carcinomatosis | completed | Phase 1 | 26 | M.D. Anderson Cancer CenterOTHER | 1 | May 22, 2025 | clinicaltrials |
| NCT06587802 | Phase II Study of PD-1 Antibody Combined With Radiotherapy in Recurrent or Metastatic Adrenal Cortical Carcinoma | recruiting | Phase 2 | 18 | Sun Yat-sen UniversityOTHER | 1 | Apr 29, 2025 | clinicaltrials |
| NCT05563467 | Pembrolizumab in the Treatment of Advanced, Progressive Adrenocortical Carcinoma.(PEMBR-01) | recruiting | Phase 2 | 24 | Maria Sklodowska-Curie National Research Institute of OncologyOTHER | 1 | Apr 2, 2025 | clinicaltrials |
| NCT06801340 | Assessment of Metabolic Complications in Patients With Adrenal Tumors Through Radiological Images | recruiting | — | 1,000 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 1 | Jan 30, 2025 | clinicaltrials |
| NCT06741423 | Distinguishing Retroperitoneal Fibrosis and Sarcoma from Other Retroperitoneal Diseases Via Radiomics | active not recruiting | — | 600 | Heidelberg UniversityOTHER | 2 | Dec 19, 2024 | clinicaltrials |
| NCT04028479 | The Registry of Oncology Outcomes Associated With Testing and Treatment(ROOT) | completed | — | 167 | Taproot HealthINDUSTRY | 1 | Dec 18, 2024 | clinicaltrials |
| NCT03370718 | Cabozantinib in Treating Patients With Locally Advanced or Metastatic Unresectable Adrenocortical Carcinoma | completed | Phase 2 | 18 | M.D. Anderson Cancer CenterOTHER | 1 | Dec 10, 2024 | clinicaltrials |
| NCT05999292 | Phase 1 Study of 68Ga-R8760 | terminated | Phase 1 | 11 | Radionetics OncologyINDUSTRY | 1 | Dec 9, 2024 | clinicaltrials |
| NCT00924989 | A Study of OSI-906 in Patients With Locally Advanced or Metastatic Adrenocortical Carcinoma(GALACCTIC) | completed | Phase 3 | 139 | Astellas Pharma IncINDUSTRY | 9 | Nov 20, 2024 | clinicaltrials |
| NCT05012397 | Milademetan in Advanced/Metastatic Solid Tumors | terminated | Phase 2 | 40 | Rain Oncology IncINDUSTRY | 1 | Oct 17, 2024 | clinicaltrials |
| NCT05631379 | Influence of Nutritional Status on Oncologic and Operative Outcome in Patients Operated for Retroperitoneal Sarcoma | completed | — | 100 | Institute of Oncology LjubljanaOTHER | 1 | Oct 17, 2024 | clinicaltrials |
| NCT06612671 | Treatment Outcomes of Retroperitoneal Sarcoma | active not recruiting | — | 150 | Taichung Veterans General HospitalOTHER | 1 | Sep 25, 2024 | clinicaltrials |
| NCT03612232 | Cabozantinib in Advanced Adrenocortical Carcinoma(CaboACC) | unknown | Phase 2 | 37 | Wuerzburg University HospitalOTHER | 1 | Aug 19, 2024 | clinicaltrials |
| NCT03723941 | Adjuvant Chemotherapy vs. Observation/Mitotane After Primary Surgical Resection of Localized Adrenocortical CarcInoma(ACACIA) | completed | Phase 3 | 40 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di BresciaOTHER | 1 | Aug 1, 2024 | clinicaltrials |
| NCT05913427 | Evaluation of the Efficacy of Addition of Progesterone to Standard Chemotherapy in Adrenocortical Carcinoma (ACC)(PESETA) | recruiting | Phase 2 | 80 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di BresciaOTHER | 1 | Aug 1, 2024 | clinicaltrials |
| NCT04318730 | Phase II Study for Combination of Camrelizumab and Apatinib in the Second-line Treatment of Recurrent or Metastatic Adrenocortical Carcinoma | unknown | Phase 2 | 21 | West China HospitalOTHER | 1 | Jul 17, 2024 | clinicaltrials |
| NCT06436846 | Genomic Risk in Retroperitoneal Sarcoma | recruiting | — | 50 | Fox Chase Cancer CenterOTHER | 1 | May 31, 2024 | clinicaltrials |
| NCT06229405 | Development of Clinical Evidence for Optimal Management of Adrenal Diseases Based on Real-World Data | unknown | — | 8,200 | Seoul National University HospitalOTHER | 1 | Mar 4, 2024 | clinicaltrials |
| NCT00304070 | Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor | completed | Phase 3 | 78 | Children's Oncology GroupNETWORK | 4 | Feb 28, 2024 | clinicaltrials |
| NCT04373265 | Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol) | completed | Phase 1 | 15 | Corcept TherapeuticsINDUSTRY | 1 | Feb 23, 2024 | clinicaltrials |
| NCT02384473 | Real-Time Contrast-Enhanced Ultrasonography and Shear Wave Elastography in Predicting Treatment Response in Patients With Soft Tissue Sarcoma | completed | Early Phase 1 | 25 | University of Southern CaliforniaOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT03792867 | Radical Resection and HIPEC for Recurrent Retroperitoneal Sarcoma | unknown | N/A | 5 | National Cancer Centre, SingaporeOTHER | 1 | Oct 11, 2023 | clinicaltrials |
| NCT06050057 | Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy | unknown | — | 100 | University Hospital OlomoucOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT05174455 | Niraparib for the Treatment of Leiomyosarcoma | withdrawn | Phase 2 | 0 | David Liebner, MDOTHER | 0 | Sep 18, 2023 | clinicaltrials |
| NCT05844813 | Neoadjuvant Chemotherapy Combined With Targeted Treatment in High-risk Retroperitoneal Sarcoma(NATARS) | enrolling by invitation | Phase 4 | 102 | Peking University International HospitalOTHER | 1 | May 12, 2023 | clinicaltrials |
| NCT05839886 | The Adverse Event of Mitotane Therapy in Patients With Adrenocortical Carcinoma(MEET) | unknown | — | 50 | Shanghai Jiao Tong University School of MedicineOTHER | 0 | May 6, 2023 | clinicaltrials |
| NCT05763524 | European Multicenter Study on Role of Lymph Node Dissection in Surgical Management of Adrenal Cortical Carcinoma(LACC) | unknown | — | 90 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 20, 2023 | clinicaltrials |
| NCT05344027 | The Impact of Mitotane Therapy on Serum Free Proteins in Patients With Adrenocortical Carcinoma(MitoS-FP) | completed | — | 35 | King's College Hospital NHS TrustOTHER | 1 | Mar 8, 2023 | clinicaltrials |
| NCT04447014 | Natural History Study of Children and Adults With Adrenocortical Cancer (ACC) | terminated | — | 15 | National Cancer Institute (NCI)NIH | 1 | Jan 17, 2023 | clinicaltrials |
| NCT05660889 | Adrenal Vein Sampling as a Tool to Identify Biomarkers That Aid the Diagnosis of Adrenocortical Carcinoma(AVS for ACC) | unknown | — | 25 | Erasmus Medical CenterOTHER | 1 | Dec 21, 2022 | clinicaltrials |
| NCT05302570 | Neoadjuvant Short-course Hypofractionated PBT for Non-metastatic RPS(PROTONS-RPS) | withdrawn | Phase 2 | 0 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Dec 15, 2022 | clinicaltrials |
| NCT05361083 | First-in-human Evaluation of [18F]CETO | completed | Early Phase 1 | 20 | Uppsala UniversityOTHER | 1 | May 4, 2022 | clinicaltrials |
| NCT02637531 | A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549 | unknown | Phase 1 | 219 | Infinity Pharmaceuticals, Inc.INDUSTRY | 1 | Apr 4, 2022 | clinicaltrials |
| NCT04225494 | Perioperative Residual Adrenal Function After Extended Resection for Retroperitoneal Soft Tissue Sarcomas(RAF) | completed | — | 52 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Oct 5, 2021 | clinicaltrials |
| NCT05044624 | Retroperıtoneal Soft-Tıssue Sarcomas | completed | N/A | 18 | Istanbul Medeniyet UniversityOTHER | 0 | Sep 16, 2021 | clinicaltrials |
| NCT03896958 | The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)(PIONEER) | unknown | — | 1,000 | SpeciCareINDUSTRY | 1 | Dec 4, 2020 | clinicaltrials |
| NCT01566123 | Trial of Neoadjuvant Intensity-Modulated Radiation Therapy Followed by Surgery and Intraoperative Radiation Therapy in Resectable Retroperitoneal Soft Tissue Sarcoma (RETRO-WTS) | completed | Phase 1 / Phase 2 | 37 | University Hospital HeidelbergOTHER | 1 | Apr 3, 2020 | clinicaltrials |
| NCT03474237 | A Prospective Cohort Study for Patients With Adrenal Diseases | enrolling by invitation | — | 1,500 | Seoul National University HospitalOTHER | 1 | Mar 18, 2020 | clinicaltrials |
| NCT01086696 | A Pilot Study of F-18 Paclitaxel (FPAC) PET for Evaluating Drug Delivery of Solid Tumors in Breast, Lung, Renal, and Adrenal Cancers | terminated | Early Phase 1 | 6 | National Cancer Institute (NCI)NIH | 1 | Dec 17, 2019 | clinicaltrials |
| NCT02015026 | Natural History and Tissue Acquisition Study of Adrenocortical Carcinoma | completed | — | 67 | National Cancer Institute (NCI)NIH | 1 | Dec 12, 2019 | clinicaltrials |
| NCT01185639 | Stereotactic Body Radiation Therapy (SBRT) in Metastatic Non-small Cell Lung Cancer | completed | N/A | 29 | Wake Forest University Health SciencesOTHER | 1 | Nov 29, 2019 | clinicaltrials |
| NCT01833832 | Surgery and Heated Chemotherapy for Adrenocortical Carcinoma | completed | Phase 2 | 11 | National Cancer Institute (NCI)NIH | 1 | Jul 30, 2019 | clinicaltrials |
| NCT02720484 | Nivolumab in Treating Patients With Metastatic Adrenocortical Cancer | terminated | Phase 2 | 10 | Northwestern UniversityOTHER | 1 | May 1, 2019 | clinicaltrials |
| NCT03877588 | Nutritional Status in Retroperitoneal Sarcoma.(NOVA) | completed | N/A | 35 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 0 | Mar 15, 2019 | clinicaltrials |
| NCT03838718 | REtroperitoneal SArcoma Registry: an International Prospective Initiative(RESAR) | recruiting | — | 2,000 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 11 | Feb 12, 2019 | clinicaltrials |
| NCT00453895 | Sunitinib in Refractory Adrenocortical Carcinoma(SIRAC) | completed | Phase 2 | 39 | University of WuerzburgOTHER | 1 | Jan 31, 2019 | clinicaltrials |
Data updated 22 days agoSource updated Sep 3, 2025source: clinicaltrials