Subtype
Malignant Colorectal Neoplasm
CI-CAN-00005874Explore in graph →
1,565 active trials21 approved drugs382 evidence items
- NCIt
- C4978
- DOID
- 9256
- Other
- 1 more code
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Subtype
CI-CAN-00005874Explore in graph →
Clinical trials
7,296 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (722)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04150705 | PET/MR for Rectal Cancer Treatment Monitoring and Surveillance | terminated | N/A | 14 | Washington University School of MedicineOTHER | 1 | Feb 14, 2023 | clinicaltrials |
| NCT03249727 | Analysis of Natural Killer Cell Activity (NKA) in Whole Blood in High Risk Subjects Undergoing Colonoscopy(ANKA-HR) | terminated | N/A | 396 | ATGen Canada IncINDUSTRY | 1 | Jan 31, 2023 | clinicaltrials |
| NCT04077372 | Assessment of a Serious Illness Conversation Guide (SICG) in Advanced Gastro-Intestinal Cancers | terminated | N/A | 12 | Stanford UniversityOTHER | 1 | Jan 27, 2023 | clinicaltrials |
| NCT01952730 | Pilot Study of GVAX in Colorectal Cancer Cells | terminated | Phase 1 | 1 | Massachusetts General HospitalOTHER | 1 | Jan 12, 2023 | clinicaltrials |
| NCT02910843 | Neoadjuvant Treatment With Regorafenib and Capecitabine Combined With Radiotherapy in Locally Advanced Rectal Cancer(RECAP) | terminated | Phase 1 | 25 | Swiss Cancer InstituteOTHER | 1 | Jan 10, 2023 | clinicaltrials |
| NCT04044430 | Encorafenib, Binimetinib, and Nivolumab in Treating Microsatellite Stable BRAF V600E Metastatic Colorectal Cancer | terminated | Phase 1 | 2 | University of California, San FranciscoOTHER | 1 | Jan 9, 2023 | clinicaltrials |
| NCT05368688 | Microbiome in Colorectal Cancer Onset and Progression | terminated | — | 63 | ViomeINDUSTRY | 1 | Dec 27, 2022 | clinicaltrials |
| NCT01882660 | Pre-operative Decitabine in Colon Cancer: a Proof of Principle Study(DECO) | terminated | N/A | 10 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Dec 19, 2022 | clinicaltrials |
| NCT05291988 | A Multilevel Approach for Improvement in Screening of Colorectal Cancer in Rural Communities, The Screen to Save Trial | terminated | N/A | 8 | Fred Hutchinson Cancer CenterOTHER | 1 | Dec 15, 2022 | clinicaltrials |
| NCT02700555 | Surveillance of Metabolic Parameters in Patients With Colorectal Cancer(SPRING) | terminated | — | 23 | Kangbuk Samsung HospitalOTHER | 1 | Dec 8, 2022 | clinicaltrials |
| NCT02437916 | Safety Study of AMG 228 to Treat Solid Tumors | terminated | Phase 1 | 30 | AmgenINDUSTRY | 5 | Nov 8, 2022 | clinicaltrials |
| NCT02597075 | Physical Activity in Patients With Metastatic Colorectal Cancer Who Receive Palliative First-line Chemotherapy | terminated | N/A | 100 | Swiss Cancer InstituteOTHER | 2 | Nov 7, 2022 | clinicaltrials |
| NCT03693846 | Nivolumab and Ipilimumab in Mucinous Colorectal and Appendiceal Tumors | terminated | Phase 2 | 11 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Oct 20, 2022 | clinicaltrials |
| NCT03827044 | Avelumab Plus 5-FU Based Chemotherapy as Adjuvant Treatment for Stage 3 MSI-High or POLE Mutant Colon Cancer(POLEM) | terminated | Phase 3 | 30 | Royal Marsden NHS Foundation TrustOTHER | 1 | Oct 7, 2022 | clinicaltrials |
| NCT03781778 | Pilot Trial of Resistant Starch in Stage I-III Colorectal Cancer Survivors | terminated | Phase 2 | 10 | Fred Hutchinson Cancer CenterOTHER | 1 | Oct 6, 2022 | clinicaltrials |
| NCT04372992 | The Stoma Closure Before or After Adjuvant Therapy Trial(STOMAD) | terminated | N/A | 14 | Ospedale Umberto I di TorinoOTHER | 1 | Sep 22, 2022 | clinicaltrials |
| NCT02363647 | Personalized Cancer Therapy for Patients With Metastatic Medullary Thyroid or Metastatic Colon Cancer | terminated | N/A | 10 | Icahn School of Medicine at Mount SinaiOTHER | 1 | Aug 31, 2022 | clinicaltrials |
| NCT05018325 | Assessing Effect of Withdrawal Time on Adenoma Detection Rate for Screening Colonoscopy | terminated | N/A | 32 | Washington University School of MedicineOTHER | 1 | Aug 31, 2022 | clinicaltrials |
| NCT05091528 | A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers | terminated | Phase 1 / Phase 2 | 2 | Silverback TherapeuticsINDUSTRY | 1 | Aug 18, 2022 | clinicaltrials |
| NCT02960282 | Gut Microbiome in Fecal Samples From Patients With Metastatic Cancer Undergoing Chemotherapy or Immunotherapy | terminated | — | 21 | University of Southern CaliforniaOTHER | 1 | Aug 10, 2022 | clinicaltrials |
| NCT03524820 | Cetuximab Therapy for Third Line Rechallenge in Metastatic Colorectal Cancer | terminated | Phase 2 | 3 | Hadassah Medical OrganizationOTHER | 1 | Aug 4, 2022 | clinicaltrials |
| NCT02300922 | Pretargeted Radioimmunotherapy in Metastatic Colorectal Cancer(RITCOLON) | terminated | Phase 1 / Phase 2 | 7 | Nantes University HospitalOTHER | 1 | Aug 1, 2022 | clinicaltrials |
| NCT02445456 | Feasibility of Sentinel Lymph Node Biopsy in Rectal Cancer(SentiRect) | terminated | N/A | 15 | Oxford University Hospitals NHS TrustOTHER | 1 | Jul 6, 2022 | clinicaltrials |
| NCT01759238 | Chemoradiotherapy for Patients With Oligometastatic Colorectal Cancer(OLGA) | terminated | Phase 2 | 1 | Universitätsklinikum Hamburg-EppendorfOTHER | 1 | Jul 1, 2022 | clinicaltrials |
| NCT03970694 | Neoadjuvant Chemoradiotherapy Versus Neoadjuvant Chemotherapy For Unresectable Locally Advanced Colon Cancer | terminated | Phase 3 | 49 | Sun Yat-sen UniversityOTHER | 1 | Jun 8, 2022 | clinicaltrials |
| NCT03475680 | Mechanical Bowel Preparation and Oral Antibiotics Before Colon Cancer Surgery(COLONPREP) | terminated | Phase 3 | 193 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | May 17, 2022 | clinicaltrials |
| NCT01507545 | Morphotek Investigation in Colorectal Cancer: Research of MORAb-004 (MICRO) | terminated | Phase 2 | 154 | MorphotekINDUSTRY | 1 | May 6, 2022 | clinicaltrials |
| NCT02423785 | Ocular Blood Flow in Colorectal Cancer Patients | terminated | — | 11 | Medical University of ViennaOTHER | 1 | Apr 29, 2022 | clinicaltrials |
| NCT02102022 | Ph 1-2 Study ADI-PEG 20 Plus FOLFOX in Subjects With Advanced GI Malignancies Focusing on Hepatocellular Carcinoma | terminated | Phase 1 / Phase 2 | 140 | Polaris GroupINDUSTRY | 6 | Apr 25, 2022 | clinicaltrials |
| NCT04627142 | A Study to Test Different Doses of BI 1701963 in Combination With Irinotecan in People With Advanced Bowel Cancer With Kirsten Rat Sarcoma Viral Oncogene Homologue (KRAS) Mutation | terminated | Phase 1 | 15 | Boehringer IngelheimINDUSTRY | 1 | Apr 20, 2022 | clinicaltrials |
| NCT02588248 | L-Menthol Injection as a Novel Technique During Colonoscopy(MINT-C) | terminated | Phase 3 | 82 | University Hospitals Cleveland Medical CenterOTHER | 1 | Apr 19, 2022 | clinicaltrials |
| NCT03875313 | Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors | terminated | Phase 1 / Phase 2 | 33 | Calithera Biosciences, IncINDUSTRY | 1 | Feb 17, 2022 | clinicaltrials |
| NCT02628535 | Safety Study of MGD009 in B7-H3-expressing Tumors | terminated | Phase 1 | 67 | MacroGenicsINDUSTRY | 3 | Feb 8, 2022 | clinicaltrials |
| NCT03099486 | Regorafenib Plus 5-Fluorouracil/Leucovorin Beyond Progression in mCRC | terminated | Phase 2 | 2 | Fox Chase Cancer CenterOTHER | 1 | Feb 7, 2022 | clinicaltrials |
| NCT04034355 | Preventive Treatment of OxaLiplatin Induced peripherAl neuRopathy in Adjuvant Colorectal Cancer(POLAR-A) | terminated | Phase 3 | 301 | Egetis TherapeuticsINDUSTRY | 10 | Jan 26, 2022 | clinicaltrials |
| NCT02465593 | A Study of PEP503(Radio-enhancer) With Radiotherapy and Chemotherapy for Patients With Rectal Cancer | terminated | Phase 1 / Phase 2 | 32 | PharmaEngineINDUSTRY | 1 | Jan 11, 2022 | clinicaltrials |
| NCT01285102 | Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From Metastatic Colon or Rectal Cancer | terminated | Phase 1 | 4 | Fox Chase Cancer CenterOTHER | 1 | Dec 20, 2021 | clinicaltrials |
| NCT03050814 | Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004 | terminated | Phase 2 | 30 | National Cancer Institute (NCI)NIH | 1 | Dec 20, 2021 | clinicaltrials |
| NCT03654729 | Preventive Treatment of Oxaliplatin Induced Peripheral Neuropathy in Metastatic Colorectal Cancer (POLAR-M)(POLAR-M) | terminated | Phase 3 | 291 | Egetis TherapeuticsINDUSTRY | 13 | Dec 17, 2021 | clinicaltrials |
| NCT01995396 | Hartmanns Procedure or Abdominoperineal Excision With Intersphincteric Dissection in Rectal Cancer: a Randomized Study(HAPIrect) | terminated | N/A | 164 | Region VästmanlandOTHER | 1 | Dec 16, 2021 | clinicaltrials |
| NCT04165031 | A Study of LY3499446 in Participants With Advanced Solid Tumors With KRAS G12C Mutation | terminated | Phase 1 / Phase 2 | 5 | Eli Lilly and CompanyINDUSTRY | 2 | Nov 24, 2021 | clinicaltrials |
| NCT02319304 | Pelvic Radiotherapy With Concurrent Neoadjuvant FOLFOX for Patients With Newly Diagnosed Rectal Adenocarcinoma(GCC 1314) | terminated | Phase 2 | 3 | University of Maryland, BaltimoreOTHER | 1 | Nov 4, 2021 | clinicaltrials |
| NCT01505166 | Randomized Phase II Adjuvant Chemotherapy ± FANG™ in Colorectal Carcinoma With Liver Metastases(FANG-CLM) | terminated | Phase 2 | 3 | Gradalis, Inc.INDUSTRY | 1 | Nov 1, 2021 | clinicaltrials |
| NCT02173990 | Aflibercept and Chemotherapy as First Line Treatment for Metastatic Colorectal Cancer Assessable With DCE-US (PULSAR).(PULSAR) | terminated | Phase 2 | 40 | Centre Oscar LambretOTHER | 1 | Oct 20, 2021 | clinicaltrials |
| NCT03699410 | Observational Study on Rectal Cancer to Verify if Response After Chemo-radiotherapy Can be Predicted With a Particular Blood Test.(LiBReCa) | terminated | — | 25 | Dimitri ChristoforidisOTHER | 1 | Oct 13, 2021 | clinicaltrials |
| NCT03176264 | PDR001 in Combination With Bevacizumab and mFOLFOX6 as First Line Therapy in Patients With Metastatic MSS Colorectal Cancer | terminated | Phase 1 | 1 | Novartis PharmaceuticalsINDUSTRY | 1 | Oct 12, 2021 | clinicaltrials |
| NCT02163785 | Abdominoperineal Extra-Elevators Rectal Resection for Cancer: Prone Position vs. Supine Position(APPRO) | terminated | N/A | 280 | Hospital Universitario La FeOTHER | 1 | Oct 1, 2021 | clinicaltrials |
| NCT04158349 | Intraperitoneal Oxaliplatin in Combo w IV mFOLFIRI for Peritoneal Carcinomatosis From Colorectal & Appendiceal Cancer(IPOX-FOLFIRI) | terminated | Phase 1 | 1 | University of UtahOTHER | 1 | Sep 27, 2021 | clinicaltrials |
| NCT03280277 | Ferumoxytol-Enhanced MRI in Imaging Lymph Nodes in Patients With Locally Advanced Rectal Cancer | terminated | Early Phase 1 | 2 | OHSU Knight Cancer InstituteOTHER | 1 | Sep 10, 2021 | clinicaltrials |
Data updated 23 days agoSource updated Feb 14, 2023source: clinicaltrials