Subtype
Malignant Colorectal Neoplasm
CI-CAN-00005874Explore in graph →
1,565 active trials21 approved drugs382 evidence items
- NCIt
- C4978
- DOID
- 9256
- Other
- 1 more code
Loading cancer entity…
Loading cancer entity…
Subtype
CI-CAN-00005874Explore in graph →
Clinical trials
7,296 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (722)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07454720 | A Clinical Study of Adebrelimab in Combination With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally Advanced Rectal Cancer | recruiting | Phase 2 / Phase 3 | 165 | Suzhou Suncadia Biopharmaceuticals Co., Ltd.INDUSTRY | 1 | May 5, 2026 | clinicaltrials |
| NCT07503756 | JS212 Combination Therapies in Metastatic Colorectal Cancer | recruiting | Phase 2 | 80 | Shanghai Junshi Bioscience Co., Ltd.OTHER | 1 | May 5, 2026 |
| NCT07566559 | Rectal Cancer Neoadjuvant Therapy-Real World Study(RC-NAT-RWS) | recruiting | — | 869 | Beijing Friendship HospitalOTHER | 1 | May 5, 2026 | clinicaltrials |
| NCT02732860 | Personalized Patient Derived Xenograft (pPDX) Modeling to Test Drug Response in Matching Host(REFLECT) | recruiting | — | 120 | University Health Network, TorontoOTHER | 1 | May 4, 2026 | clinicaltrials |
| NCT04511039 | Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer | recruiting | Phase 1 | 45 | Roswell Park Cancer InstituteOTHER | 1 | May 4, 2026 | clinicaltrials |
| NCT06111105 | GUIDE.MRD-01-CRC: Clinical Validation and Benchmarking of Top Performing ctDNA Diagnostics - Colorectal Cancer | recruiting | — | 590 | Claus Lindbjerg AndersenOTHER | 5 | May 4, 2026 | clinicaltrials |
| NCT06614647 | RESPONSE: Colorectal Cancer Survivors' Follow-up Care - Now Digital and Need-based(RESPONSE) | recruiting | N/A | 400 | University of AarhusOTHER | 1 | May 4, 2026 | clinicaltrials |
| NCT02781337 | Epidemiological and Molecular Colorectal Cancer Registry(EMR-CRC) | recruiting | — | 2,100 | Hospital Italiano de Buenos AiresOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT02838836 | Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers | recruiting | — | 620 | University of Missouri-ColumbiaOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT07283367 | A Phase Ib/II Trial of HS-20110 Combination Therapies in Advanced Colorectal Cancer Patients. | recruiting | Phase 1 / Phase 2 | 502 | Hansoh BioMedical R&D CompanyINDUSTRY | 1 | May 1, 2026 | clinicaltrials |
| NCT07561060 | Low Rectal Cancer Treated With Total Neoadjuvant Therapy Plus Concurrent Tislelizumab Immunotherapy(TNTIT) | recruiting | Phase 1 / Phase 2 | 50 | Fudan UniversityOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT07562490 | A Randomized Controlled Trial of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy Decision-Making in High-Risk Stage III (T4N+ or T1-3N2) Colorectal Cancer(CLEAR-04) | recruiting | Phase 2 | 100 | Fudan UniversityOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT07562503 | Randomized Trial of Plasma ctDNA Methylation-Guided Adjuvant Therapy in T4N0 and Low-Risk Stage III Colorectal Cancer(CLEAR-03) | recruiting | Phase 2 | 340 | Fudan UniversityOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT07562659 | Randomized Controlled Study of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy in Stage I/Low-Risk Stage II Colorectal Cancer(CLEAR-01) | recruiting | Phase 2 | 80 | Fudan UniversityOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT07562711 | Randomized Study of Plasma ctDNA Methylation to Guide Adjuvant Chemotherapy Decisions in High-Risk T3N0 Colorectal Cancer(CLEAR-02) | recruiting | Phase 2 | 340 | Fudan UniversityOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT01762813 | Assessment of Clinically Related Outcomes and Biomarker Analysis for Translational Integration in Colorectal Cancer(ACROBATICC) | recruiting | — | 1,200 | Helse Stavanger HFOTHER_GOV | 1 | Apr 30, 2026 | clinicaltrials |
| NCT05726136 | Fluid Challenge and Plasma Volume, During Surgery(FC-VE) | recruiting | Phase 4 | 60 | Joachim ZdolsekOTHER | 1 | Apr 30, 2026 | clinicaltrials |
| NCT07171554 | Evaluation of a Diagnostic Test to Identify the Best Drugs for Treatment of Metastatic Colorectal Cancer(DSEE-CRC) | recruiting | N/A | 75 | Oncosyne ASINDUSTRY | 1 | Apr 30, 2026 | clinicaltrials |
| NCT07528209 | Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer | recruiting | Phase 3 | 556 | Sun Yat-sen UniversityOTHER | 1 | Apr 30, 2026 | clinicaltrials |
| NCT07558083 | FOLICOLOR TRIAL: Following Therapy Response Through Liquid Biopsy in Metatstatic Colorectal Cancer Patients(FOLICOLOR) | recruiting | Phase 3 | 150 | University Hospital, AntwerpOTHER | 1 | Apr 30, 2026 | clinicaltrials |
| NCT07559760 | New Second-Line Combo Therapy for MSS Metastatic Colorectal Cancer | recruiting | Phase 2 | 30 | The First Hospital of Jilin UniversityOTHER | 1 | Apr 30, 2026 | clinicaltrials |
| NCT07559825 | Early-Onset Colorectal Cancer Patients Too Young for Screening | recruiting | — | 100 | Methodist Health SystemOTHER | 1 | Apr 30, 2026 | clinicaltrials |
| NCT06356584 | Fruquintinib Combined With Sintilimab ± Radiotherapy for Third-line Treatment of Colorectal Cancer With Liver Metastases | recruiting | Phase 2 | 62 | Shandong Cancer Hospital and InstituteOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT06589830 | TL938 and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer | recruiting | Phase 2 | 80 | Suzhou Teligene Ltd.INDUSTRY | 1 | Apr 28, 2026 | clinicaltrials |
| NCT06850090 | Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III Trial | recruiting | Phase 3 | 210 | Shandong Cancer Hospital and InstituteOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT07189312 | Multi-scale Spatio-Temporal Analysis of Research Data(MuSTARD) | recruiting | — | 15 | Universidad de GranadaOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT07553572 | Remote Monitoring and Symptom Management Digital Application(ASSIST) | recruiting | N/A | 60 | Patrick C. Johnson, MDOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT04643041 | Watch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal Cancer(BASKET) | recruiting | N/A | 47 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 27, 2026 | clinicaltrials |
| NCT06002789 | Safety and Efficacy of PD-1 ± mFOLFOX6 Neoadjuvant Therapy in Local Advanced sMPCC | recruiting | Phase 2 | 17 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 27, 2026 | clinicaltrials |
| NCT06723236 | A Study of MGC028 in Participants With Advanced Solid Tumors | recruiting | Phase 1 | 124 | MacroGenicsINDUSTRY | 1 | Apr 27, 2026 | clinicaltrials |
| NCT07552467 | Sub-topic Four: Clinical Translation of Original Radioactive Drugs for Precision Diagnosis and Treatment of Gastrointestinal Tumors -Clinical Application Value of PET Imaging Targeting LRRC15 in Malignant Tumors | recruiting | — | 26 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Apr 27, 2026 | clinicaltrials |
| NCT03841799 | COLON-IM : Microbiota and Immune Infiltrate in Normal, Dysplastic and Neoplastic Colorectal Tissue | recruiting | — | 400 | Centre Leon BerardOTHER | 1 | Apr 24, 2026 | clinicaltrials |
| NCT05732623 | Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer(DEMETRA) | recruiting | — | 2,300 | San Raffaele UniversityOTHER | 6 | Apr 24, 2026 | clinicaltrials |
| NCT06204094 | Node-sparing Radiotherapy Combined With Total Neoadjuvant CAPOX and Sintilimab for MSS Middle and Low Rectal Cancer(CASINOs) | recruiting | Phase 2 | 37 | Jinhua Central HospitalOTHER | 1 | Apr 24, 2026 | clinicaltrials |
| NCT04450758 | Acute Colon Resection Versus Bridge to Colon Surgery With Stent or Stoma(ACBC) | recruiting | — | 1,000 | Skane University HospitalOTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT05523245 | Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Based on Multi-parametric MRI(DLARC) | recruiting | — | 1,700 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT06475352 | Dose Individualization of Chemotherapy in Patients With Gastrointestinal Cancers Lacking a Specific Liver Enzyme(FUDOSE) | recruiting | Phase 2 | 400 | UNICANCEROTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT06720987 | A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies | recruiting | Phase 1 | 140 | Kumquat Biosciences Inc.INDUSTRY | 1 | Apr 23, 2026 | clinicaltrials |
| NCT06957015 | A Prospective Study to Evaluate the Performance of a Real-time System in the Estimation of Colorectal Polyp Size(EndoAIM) | recruiting | N/A | 278 | Chinese University of Hong KongOTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT07381322 | A Study on the Accurate Evaluation of Pseudoprogression of Rectal Cancer Immunotherapy Based on Multitemporal and Multiparameter MRI | recruiting | — | 300 | Peiyi XieOTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT06965166 | Contrast-Enhanced Photon-Counting Detector CT (PCD-CT) for the Local Staging of Rectal Cancer | recruiting | — | 200 | Mayo ClinicOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT07020221 | A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors | recruiting | Phase 1 / Phase 2 | 295 | Verastem, Inc.INDUSTRY | 2 | Apr 22, 2026 | clinicaltrials |
| NCT07198581 | AI-Assisted Chemotherapy Side Effect Management(ALLIANCE) | recruiting | N/A | 174 | Incheon St.Mary's HospitalOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT07412613 | Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer | recruiting | Phase 3 | 386 | AkesoINDUSTRY | 1 | Apr 22, 2026 | clinicaltrials |
| NCT07546565 | Mechanical Bowel Preparation in Laparoscopic Right Hemicolectomy With Intracorporeal Anastomosis(UMC-Colprep) | recruiting | N/A | 74 | University Medical Center Ho Chi Minh City (UMC)OTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT06424522 | A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients | recruiting | N/A | 80 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT07393048 | Application and Exploration of Personalized ctDNA-MRD Detection Technology in Predicting the Efficacy of Neoadjuvant Therapy for Rectal Cancer(ctDNA-MRD-RC) | recruiting | — | 60 | Beijing Friendship HospitalOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT07407647 | Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer | recruiting | Phase 2 | 25 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Apr 21, 2026 | clinicaltrials |
Data updated 23 days agoSource updated May 5, 2026source: clinicaltrials