Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00574171 | Phase II Trial of Lapatinib & Capecitabine for Patients With Refractory Advanced Colorectal Adenocarcinoma | completed | Phase 2 | 29 | University of Wisconsin, MadisonOTHER | 1 | Dec 18, 2019 | clinicaltrials |
| NCT02541370 | Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133 | completed | Phase 1 / Phase 2 | 20 | Chinese PLA General HospitalOTHER | 1 | Dec 17, 2019 | clinicaltrials |
| NCT00205322 | Oxaliplatin, 5-FU and Leucovorin in Combination With Oral Capecitabine for Metastatic Colorectal Cancer | completed | Phase 2 | 45 | University of Wisconsin, MadisonOTHER | 1 | Nov 19, 2019 | clinicaltrials |
| NCT00508404 | Panitumumab Plus FOLFIRI in First-line Treatment of Metastatic Colorectal Cancer | completed | Phase 2 | 154 | AmgenINDUSTRY | 0 | Nov 19, 2019 | clinicaltrials |
| NCT03246321 | PIPAC for Peritoneal Metastases of Colorectal Cancer(CRC-PIPAC) | completed | Phase 2 | 20 | Koen RoversOTHER | 1 | Oct 15, 2019 | clinicaltrials |
| NCT01251536 | Cetuximab Standard or Dose Escalation in First Line Colorectal Cancer(Everest2) | completed | Phase 2 | 108 | Universitaire Ziekenhuizen KU LeuvenOTHER | 5 | Oct 11, 2019 | clinicaltrials |
| NCT01650428 | Bevacizumab And Combination Chemotherapy in Rectal Cancer Until Surgery(BACCHUS) | completed | Phase 2 | 20 | University College, LondonOTHER | 1 | Oct 7, 2019 | clinicaltrials |
| NCT01806675 | 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy | completed | Phase 1 / Phase 2 | 25 | Sanjiv Sam GambhirOTHER | 1 | Oct 3, 2019 | clinicaltrials |
| NCT03053544 | Metformin With Neoadjuvant Chemoradiation to Improve Pathologic Responses in Rectal Cancer | completed | Phase 2 | 15 | Sunnybrook Health Sciences CentreOTHER | 1 | Sep 27, 2019 | clinicaltrials |
| NCT02119026 | Efficacy And Safety Of Xeliri + Avastin Followed By Xelox + Avastin Or Reverse Sequence In Metastatic Colorectal Cancer(PASSION) | completed | Phase 2 | 120 | Prof. Dr. Werner ScheithauerOTHER | 1 | Sep 25, 2019 | clinicaltrials |
| NCT01490866 | A Trial of Single Agent Axitinib as Maintenance Therapy for Patients With First Line Metastatic Colorectal Cancer (mCRC) | completed | Phase 2 | 70 | SCRI Development Innovations, LLCOTHER | 1 | Sep 24, 2019 | clinicaltrials |
| NCT01802320 | Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery | completed | Phase 2 | 18 | National Cancer Institute (NCI)NIH | 1 | Sep 20, 2019 | clinicaltrials |
| NCT01362361 | TRICC-C (AIO-KRK-0111): BIBF 1120 Versus Placebo in Patients Receiving Oxaliplatin Plus Fluorouracil and Leucovorin (mFOLFOX6) for Advanced, Chemorefractory Metastatic Colorectal Cancer (mCRC)(AIO-KRK-0111) | completed | Phase 2 | 54 | Martin-Luther-Universität Halle-WittenbergOTHER | 1 | Sep 19, 2019 | clinicaltrials |
| NCT01059643 | A Study in Ovarian, Non-Small Cell Lung, Prostate, Colorectal, Gastroesophageal Cancers, and Squamous Cell Carcinoma of the Head and Neck | completed | Phase 2 | 103 | Eli Lilly and CompanyINDUSTRY | 1 | Sep 18, 2019 | clinicaltrials |
| NCT02260440 | A Phase 2 Study of Pembrolizumab (MK-3475) in Combination With Azacitidine in Subjects With Chemo-refractory Metastatic Colorectal Cancer | completed | Phase 2 | 31 | Anuradha KrishnamurthyOTHER | 1 | Sep 17, 2019 | clinicaltrials |
| NCT02176746 | A Phase I/II Study of Active Immunotherapy With Cancer Stem Cells Vaccine for Colorectal Cancer(CSC) | completed | Phase 1 / Phase 2 | 40 | Fuda Cancer Hospital, GuangzhouOTHER | 1 | Sep 12, 2019 | clinicaltrials |
| NCT02651415 | Phase II Study of Perindopril and Regorafenib in mCRC(PARICCA) | completed | Phase 2 | 12 | British Columbia Cancer AgencyOTHER | 1 | Sep 12, 2019 | clinicaltrials |
| NCT03008499 | High-activity Natural Killer Immunotherapy for Small Metastases of Colorectal Cancer | completed | Phase 1 / Phase 2 | 20 | Fuda Cancer Hospital, GuangzhouOTHER | 1 | Sep 12, 2019 | clinicaltrials |
| NCT03357276 | Mix Vaccine for Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 30 | Fuda Cancer Hospital, GuangzhouOTHER | 1 | Sep 12, 2019 | clinicaltrials |
| NCT01862003 | Phase I/II Trial of Antagonism of HER in GI Cancer(PANTHER) | completed | Phase 2 | 24 | University College, LondonOTHER | 1 | Aug 19, 2019 | clinicaltrials |
| NCT01662752 | Lymphatic Mapping for Sentinel Node Identification and Analysis | completed | Phase 2 | 30 | Imperial College LondonOTHER | 1 | Aug 9, 2019 | clinicaltrials |
| NCT02086656 | PERIOPERATIVE TREATMENT WITH COI-B (CAPECITABINE, OXALIPLATIN, IRINOTECAN AND BEVACIZUMAB) OF HIGH RISK OR BORDERLINE RESECTABLE COLORECTAL CANCER LIVER METASTASES(COI-B) | completed | Phase 2 | 46 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Aug 7, 2019 | clinicaltrials |
| NCT01111604 | A Study of Ramucirumab or Icrucumab in Colorectal Cancer | completed | Phase 2 | 158 | Eli Lilly and CompanyINDUSTRY | 2 | Aug 6, 2019 | clinicaltrials |
| NCT02613221 | A Phase I/II Study for the Safety and Efficacy of Panitumumab in Combination With TAS-102 for Patients With Colorectal Cancer(APOLLON) | completed | Phase 1 / Phase 2 | 56 | TakedaINDUSTRY | 1 | Jul 31, 2019 | clinicaltrials |
| NCT02973672 | Phase I of SGM-101 in Patients With Cancer of the Colon, Rectum or Pancreas | completed | Phase 1 / Phase 2 | 75 | SurgimabINDUSTRY | 1 | Jul 18, 2019 | clinicaltrials |
| NCT03258398 | A Study to Evaluate eFT508 Alone and in Combination With Avelumab in Subjects With MSS Colorectal Cancer | completed | Phase 2 | 56 | Effector TherapeuticsINDUSTRY | 1 | Jul 18, 2019 | clinicaltrials |
| NCT00828672 | Neoadjuvant Bevacizumab, Capecitabine and Radiation Therapy With or Without Oxaliplatin Locally Advanced Rectal Cancer(AXEBEAM) | completed | Phase 2 | 84 | Universitaire Ziekenhuizen KU LeuvenOTHER | 1 | Jul 10, 2019 | clinicaltrials |
| NCT00004187 | Capecitabine and Oxaliplatin in Treating Patients With Advanced or Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | — | Swiss Cancer InstituteOTHER | 1 | Jun 26, 2019 | clinicaltrials |
| NCT02332499 | Study of Anlotinib in Patients With Metastatic Colorectal Cancer（mCRC）(ALTER0703)(ALTER0703) | completed | Phase 2 / Phase 3 | 419 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | May 21, 2019 | clinicaltrials |
| NCT00869570 | External-Beam Radiation Therapy, Capecitabine, and Sorafenib in Treating Patients With Locally Advanced Rectal Cancer | completed | Phase 1 / Phase 2 | 54 | Swiss Cancer InstituteOTHER | 2 | May 15, 2019 | clinicaltrials |
| NCT01260415 | A Study of Perioperative Chemotherapy Plus Panitumumab in Patients With Colorectal Cancer Liver Metastases | completed | Phase 2 | 11 | University Health Network, TorontoOTHER | 1 | May 14, 2019 | clinicaltrials |
| NCT01985763 | Genistein in Treatment of Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 13 | Sofya PintovaOTHER | 1 | May 10, 2019 | clinicaltrials |
| NCT00940316 | Dual Epidermal Growth Factor Receptor Inhibition With Erlotinib and Panitumumab With or Without Chemotherapy for Advanced Colorectal Cancer | completed | Phase 2 | 28 | Northwestern UniversityOTHER | 1 | May 7, 2019 | clinicaltrials |
| NCT00419159 | Efficacy and Safety of Everolimus in Patients With Metastatic Colorectal Cancer Who Have Failed Prior Targeted Therapy and Chemotherapy | completed | Phase 2 | 199 | Novartis PharmaceuticalsINDUSTRY | 1 | Apr 23, 2019 | clinicaltrials |
| NCT01206530 | FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer | completed | Phase 1 / Phase 2 | 50 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Apr 18, 2019 | clinicaltrials |
| NCT00088413 | PANVAC-V and PANVAC-F Vaccines Plus Sargramostim to Treat Advanced Cancer | completed | Phase 1 / Phase 2 | 51 | National Cancer Institute (NCI)NIH | 1 | Apr 16, 2019 | clinicaltrials |
| NCT02083653 | Sym004 vs Standard of Care in Subjects With Metastatic Colorectal Cancer | completed | Phase 2 | 254 | Symphogen A/SINDUSTRY | 10 | Apr 16, 2019 | clinicaltrials |
| NCT02970916 | Phase II Trial to Assess FOLFIRI+Aflibercept Efficacy in Patients With Oxaliplatin-pretreated Metastatic Colorectal Cancer With or Without ACE Polymorphisms(POLAF) | completed | Phase 2 | 100 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Apr 11, 2019 | clinicaltrials |
| NCT01550055 | Study of CMAB009 to Treat KRAS Wild Type Metastatic Colorectal Cancer(CRC009) | completed | Phase 2 / Phase 3 | 512 | Shanghai Zhangjiang Biotechnology Limited CompanyINDUSTRY | 0 | Apr 10, 2019 | clinicaltrials |
| NCT01051596 | A Study of ABT-888 in Combination With Temozolomide for Colorectal Cancer | completed | Phase 2 | 75 | Georgetown UniversityOTHER | 1 | Apr 2, 2019 | clinicaltrials |
| NCT00645710 | Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery | completed | Phase 1 / Phase 2 | 16 | City of Hope Medical CenterOTHER | 1 | Mar 28, 2019 | clinicaltrials |
| NCT00321685 | Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer | completed | Phase 2 | 57 | National Cancer Institute (NCI)NIH | 1 | Mar 27, 2019 | clinicaltrials |
| NCT01717391 | [F-18] Fluorothymidine PET/CT Imaging for Pelvic Cancers | completed | Phase 2 | 36 | John M. BuattiOTHER | 1 | Mar 26, 2019 | clinicaltrials |
| NCT00409994 | Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer | completed | Phase 1 / Phase 2 | 44 | Maastricht Radiation OncologyOTHER | 1 | Mar 18, 2019 | clinicaltrials |
| NCT00776399 | Radiofrequency Ablation in Resectable Colorectal Lung Metastasis | completed | Phase 2 | 70 | Mie UniversityOTHER | 1 | Mar 7, 2019 | clinicaltrials |
| NCT01312467 | Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI | completed | Phase 2 | 45 | National Cancer Institute (NCI)NIH | 2 | Mar 5, 2019 | clinicaltrials |
| NCT01290536 | Yttrium-90 Radioembolization Using Glass Microspheres (TheraSphere) for Patients With Liver Metastases | completed | Phase 2 | 42 | Nicholas Fidelman, MDOTHER | 0 | Mar 1, 2019 | clinicaltrials |
| NCT02699073 | Evaluation of Treatment Response With CHOI and RECIST Criteria and CT Texture Analysis in Patients With Metastatic Colorectal Cancer Treated With Regorafenib(TEXCAN) | completed | Phase 2 | 55 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Feb 28, 2019 | clinicaltrials |
Data updated 23 days agoSource updated Dec 18, 2019source: clinicaltrials