Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02164916 | S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer | completed | Phase 2 | 106 | SWOG Cancer Research NetworkNETWORK | 1 | Dec 30, 2020 | clinicaltrials |
| NCT01703390 | Biomarker Directed Treatment in Metastatic Colorectal Cancer | completed | Phase 2 | 47 | Arbeitsgemeinschaft medikamentoese TumortherapieOTHER | 1 | Dec 21, 2020 | clinicaltrials |
| NCT00748215 | Calcium Aluminosilicate Anti-Diarrheal in Treating and Preventing Diarrhea in Patients With Metastatic Colorectal Cancer Receiving Irinotecan | completed | Phase 2 | 100 | M.D. Anderson Cancer CenterOTHER | 1 | Dec 2, 2020 | clinicaltrials |
| NCT00628810 | Combination Chemotherapy and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 86 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Nov 9, 2020 | clinicaltrials |
| NCT01417494 | 1st Line Chemotherapy Alone or With Bevacizumab in Treating Older Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 102 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Nov 3, 2020 | clinicaltrials |
| NCT01867697 | Nordic 8 - A Phase II Trial | completed | Phase 2 | 173 | Per PfeifferOTHER | 3 | Oct 30, 2020 | clinicaltrials |
| NCT00006366 | Radiation Therapy Plus Chemotherapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum | completed | Phase 2 | — | Radiation Therapy Oncology GroupNETWORK | 2 | Oct 22, 2020 | clinicaltrials |
| NCT01858649 | Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Bevacizumab With FOLFOX or FOLFIRI.(BEV-ONCO2012) | completed | Phase 2 | 60 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | Oct 22, 2020 | clinicaltrials |
| NCT02469480 | Intravenous Ferric Carboxymaltose vs. Oral Iron Substitution in Patients With Metastatic Colorectal Cancer (CRC) and Iron Deficiency Anemia: a Randomized Multicenter Treatment Optimization Study. | completed | Phase 2 | 64 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus NordwestOTHER | 1 | Oct 19, 2020 | clinicaltrials |
| NCT01896856 | Phase I/II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 118 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 2 | Oct 6, 2020 | clinicaltrials |
| NCT03152565 | Avelumab Plus Autologous Dendritic Cell Vaccine in Pre-treated Metastatic Colorectal Cancer Patients(AVEVAC) | completed | Phase 1 / Phase 2 | 28 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | Oct 6, 2020 | clinicaltrials |
| NCT00033371 | Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis | completed | Phase 2 | 205 | National Cancer Institute (NCI)NIH | 1 | Sep 29, 2020 | clinicaltrials |
| NCT01681472 | PK/PD Investigation of Modufolin (Arfolitixorin) in Plasma, Tumor and Adjacent Mucosa Adjacent Mucosa in Patients With Colon Cancer | completed | Phase 1 / Phase 2 | 32 | Isofol Medical ABINDUSTRY | 1 | Sep 25, 2020 | clinicaltrials |
| NCT01397305 | An Extended Feasibility Phase I/II Study of Methylenetetrahydrofolate (Arfolitixorin) and Pemetrexed Single Agent, Given as Neoadjuvant Treatment in Patients With Resectable Rectal Cancer | completed | Phase 1 / Phase 2 | 24 | Isofol Medical ABINDUSTRY | 1 | Sep 9, 2020 | clinicaltrials |
| NCT02244632 | Modufolin (Arfolitixorin) in Combination With 5-Fluorouracil Alone or Together With Oxaliplatin or Irinotecan in Colorectal Cancer | completed | Phase 1 / Phase 2 | 105 | Isofol Medical ABINDUSTRY | 4 | Sep 9, 2020 | clinicaltrials |
| NCT01209325 | Vaccine Therapy in Preventing Human Papillomavirus Infection in Young HIV-Positive Male Patients Who Have Sex With Males | completed | Phase 2 | 149 | AIDS Malignancy ConsortiumNETWORK | 2 | Aug 11, 2020 | clinicaltrials |
| NCT00192114 | Enzastaurin for Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 28 | Eli Lilly and CompanyINDUSTRY | 2 | Aug 6, 2020 | clinicaltrials |
| NCT00003225 | Amifostine Plus Irinotecan in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 23 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT00002933 | Irinotecan in Treating Patients With Metastatic or Recurrent Colorectal Cancer | completed | Phase 2 | 21 | Case Comprehensive Cancer CenterOTHER | 1 | Jul 27, 2020 | clinicaltrials |
| NCT00437268 | A Study of Irinotecan Plus Cetuximab With or Without Enzastaurin in Participants With Colorectal Cancer | completed | Phase 2 | 26 | Eli Lilly and CompanyINDUSTRY | 1 | Jul 21, 2020 | clinicaltrials |
| NCT00612586 | Study of Enzastaurin With 5-Fluorouracil/Leucovorin (5-FU/LV) Plus Bevacizumab as Maintenance Regimen Following First Line Therapy for Metastatic Colon Cancer | completed | Phase 2 | 117 | Eli Lilly and CompanyINDUSTRY | 6 | Jul 21, 2020 | clinicaltrials |
| NCT03168139 | Olaptesed (NOX-A12) Alone and in Combination With Pembrolizumab in Colorectal and Pancreatic Cancer(Keynote-559) | completed | Phase 1 / Phase 2 | 20 | TME Pharma AGINDUSTRY | 1 | Jul 8, 2020 | clinicaltrials |
| NCT00867334 | New Individualized Therapy Trial for Metastatic Colorectal Cancer(NITMEC) | completed | Phase 1 / Phase 2 | 10 | Inova Health Care ServicesOTHER | 1 | Jun 30, 2020 | clinicaltrials |
| NCT01832467 | Cetuximab Rechallenge Study | completed | Phase 2 | 17 | Chinese University of Hong KongOTHER | 1 | Jun 18, 2020 | clinicaltrials |
| NCT02497157 | Bevacizumab + Triplet Treatment for Untreated With Chemotherapy Metastatic Colorectal Cancer(BeTRI) | completed | Phase 2 | 45 | Translational Research Center for Medical Innovation, Kobe, Hyogo, JapanOTHER | 1 | Jun 17, 2020 | clinicaltrials |
| NCT02196688 | Study of Fruquintinib in Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 71 | Hutchison Medipharma LimitedINDUSTRY | 1 | Jun 16, 2020 | clinicaltrials |
| NCT01363843 | Complete Neoadjuvant Treatment for REctal Cancer (CONTRE) | completed | Phase 2 | 39 | William Sikov MDOTHER | 1 | Jun 11, 2020 | clinicaltrials |
| NCT00021398 | Radiation Therapy and Chemotherapy Followed by Surgery and Combination Chemotherapy in Treating Patients With Rectal Cancer | completed | Phase 2 | 23 | Fox Chase Cancer CenterOTHER | 1 | Jun 5, 2020 | clinicaltrials |
| NCT00967616 | Study of CS-7017 in Combination With FOLFIRI in Subjects With Metastatic Colorectal Cancer Who Failed First-Line Therapy | completed | Phase 2 | 100 | Daiichi SankyoINDUSTRY | 5 | May 4, 2020 | clinicaltrials |
| NCT00622440 | Treatment of Anal High-grade Squamous Intraepithelial Lesions (HSIL) Through Use of a Chinese Herbal Topical Cream(AIJP) | completed | Phase 2 | 70 | University of California, San FranciscoOTHER | 1 | Apr 24, 2020 | clinicaltrials |
| NCT02103062 | Phase 2 Study With Abraxane (Nab®Paclitaxel) in Metastatic Colorectal Cancer | completed | Phase 2 | 41 | CelgeneINDUSTRY | 1 | Apr 21, 2020 | clinicaltrials |
| NCT01193517 | Azacitidine and CAPOX in Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 26 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 15, 2020 | clinicaltrials |
| NCT00028015 | SarCNU in Treating Patients With Recurrent or Metastatic Colorectal Cancer | completed | Phase 2 | 18 | NCIC Clinical Trials GroupNETWORK | 1 | Apr 9, 2020 | clinicaltrials |
| NCT00444678 | Cetuximab Plus Biweekly Capecitabine and Oxaliplatin in KRAS Wild Type Metastatic Colorectal Cancer | completed | Phase 2 | 36 | NYU Langone HealthOTHER | 1 | Apr 3, 2020 | clinicaltrials |
| NCT02063529 | FOLFOXIRI With or Without Cetuximab as First-line Treatment of Patients With Non-resectable Liver - Only Metastatic Colorectal Cancer(FOCULM) | completed | Phase 2 | 101 | Sun Yat-sen UniversityOTHER | 1 | Mar 31, 2020 | clinicaltrials |
| NCT00541125 | G-CSF in Preventing Neutropenia During First-Line Treatment With Chemotherapy and Bevacizumab in Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 20 | Federation Francophone de Cancerologie DigestiveOTHER | 0 | Mar 30, 2020 | clinicaltrials |
| NCT00952029 | Combination Chemotherapy and Bevacizumab With or Without Bevacizumab Maintenance Therapy in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 / Phase 3 | 492 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Mar 30, 2020 | clinicaltrials |
| NCT01674309 | First Line Treatment by FOLFIRINOX for Patients With a Rectum Cancer With Synchronous Non Resectable Metastasis | completed | Phase 2 | 65 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Mar 30, 2020 | clinicaltrials |
| NCT01906008 | Phase II Study of Minocycline for Reducing Symptom Burden in Colorectal Patients | completed | Phase 2 | 122 | M.D. Anderson Cancer CenterOTHER | 1 | Mar 17, 2020 | clinicaltrials |
| NCT00272324 | Aspirin/Folate Prevention of Large Bowel Polyps | completed | Phase 2 / Phase 3 | 1,121 | Dartmouth-Hitchcock Medical CenterOTHER | 2 | Mar 13, 2020 | clinicaltrials |
| NCT02028442 | Phase I / II Study of Enadenotucirev by Sub-acute Fractionated IV Dosing in Cancer Patients(EVOLVE) | completed | Phase 1 / Phase 2 | 61 | Akamis BioINDUSTRY | 2 | Mar 12, 2020 | clinicaltrials |
| NCT02835924 | Study Comparing Different Dose Approaches of Induction Treatment of Regorafenib in MCRC(RE-ARRANGE) | completed | Phase 2 | 299 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Mar 10, 2020 | clinicaltrials |
| NCT00081289 | Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer | completed | Phase 2 | 146 | Radiation Therapy Oncology GroupNETWORK | 1 | Feb 27, 2020 | clinicaltrials |
| NCT01744340 | A Dose Finding Study of Eribulin Mesylate and Cetuximab For Patients With Advanced Head and Neck and Colon Cancer | completed | Phase 1 / Phase 2 | 23 | howard safranOTHER | 1 | Feb 17, 2020 | clinicaltrials |
| NCT01975077 | A Phase Ib Study of Fruquintinib in 3rd Line mCRC | completed | Phase 1 / Phase 2 | 62 | Hutchison Medipharma LimitedINDUSTRY | 1 | Feb 17, 2020 | clinicaltrials |
| NCT02280694 | Low Dose Metronomic Poly-chemotherapy for Metastatic CRC(LDMchemoCRC) | completed | Phase 2 | 45 | HaEmek Medical Center, IsraelOTHER | 1 | Feb 12, 2020 | clinicaltrials |
| NCT01065441 | Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer | completed | Phase 1 / Phase 2 | 9 | Michael Har-NoyINDUSTRY | 1 | Jan 22, 2020 | clinicaltrials |
| NCT01730586 | Abraxane in CIMP-High Colorectal and Small Bowel Adenocarcinomas | completed | Phase 2 | 34 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 18, 2020 | clinicaltrials |
| NCT03190616 | Apatinib in Refractory Colorectal Cancer | completed | Phase 2 | 54 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Jan 14, 2020 | clinicaltrials |
| NCT02723578 | Pemetrexed and Erlotinib for Metastatic Colorectal Cancer | completed | Phase 2 | 50 | Yonsei UniversityOTHER | 1 | Jan 13, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Dec 30, 2020source: clinicaltrials