Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00685568 | Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis | completed | Phase 1 | 22 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 7, 2018 | clinicaltrials |
| NCT01661972 | Phase I/II Study of Capecitabine Plus Aflibercept to Treat Metastatic Colorectal Cancer(X-TRAP) | completed | Phase 1 / Phase 2 | 63 | John Strickler, M.D.OTHER | 1 | Oct 29, 2018 |
| clinicaltrials |
| NCT02718430 | VXM01 Phase I Study in Patients With Metastatic Colorectal Cancer With Liver Metastasis | completed | Phase 1 | 6 | Vaximm GmbHINDUSTRY | 1 | Oct 19, 2018 | clinicaltrials |
| NCT01117428 | Sym004 in Patients With Advanced Solid Tumors | completed | Phase 1 / Phase 2 | 111 | Symphogen A/SINDUSTRY | 3 | Oct 15, 2018 | clinicaltrials |
| NCT03356158 | A Study of Recombinant Anti-EGFR Monoclonal Antibody in Patients With Metastatic Colorectal Cancer | unknown | Phase 1 | 21 | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.INDUSTRY | 1 | Sep 17, 2018 | clinicaltrials |
| NCT02191761 | Safety and Pharmacokinetics of SM04755 in Subjects With Advanced Colorectal, Gastric, Hepatic, or Pancreatic Cancer | completed | Phase 1 | 13 | Biosplice Therapeutics, Inc.INDUSTRY | 1 | Sep 7, 2018 | clinicaltrials |
| NCT02650635 | TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic, Persistent, Recurrent, or Progressive Solid Tumors | terminated | Phase 1 | 4 | Mayo ClinicOTHER | 1 | Sep 5, 2018 | clinicaltrials |
| NCT03182894 | Epacadostat in Combination With Pembrolizumab and Azacitidine in Subjects With Metastatic Colorectal Cancer | withdrawn | Phase 1 / Phase 2 | 0 | James J LeeOTHER | 1 | Aug 28, 2018 | clinicaltrials |
| NCT02450656 | Afatinib and Selumetinib in Advanced KRAS Mutant and PIK3CA Wildtype Non-small Cell Lung Cancer(M14AFS) | unknown | Phase 1 / Phase 2 | 320 | The Netherlands Cancer InstituteOTHER | 1 | Aug 27, 2018 | clinicaltrials |
| NCT02611661 | Local Ablative Strategies After Endovascular Radioembolization(LASER) | terminated | Phase 1 | 9 | Washington University School of MedicineOTHER | 1 | Aug 16, 2018 | clinicaltrials |
| NCT00925015 | Phase I Study of Dalotuzumab (MK-0646) in Combination With Cetuximab and Irinotecan in Participants With Colorectal Cancer (MK-0646-016) | completed | Phase 1 | 20 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Aug 15, 2018 | clinicaltrials |
| NCT00458809 | Intraperitoneal Hyperthermic Perfusion With Oxaliplatin in Treating Patients With Stage IV Peritoneal Cancer Due to Appendix Cancer or Colorectal Cancer | completed | Phase 1 | 16 | Wake Forest University Health SciencesOTHER | 1 | Aug 9, 2018 | clinicaltrials |
| NCT03545711 | Safety and Efficacy of Anlotinib in Combination With Irinotecan in Patients With Pretreated Advanced Colorectal Cancer | unknown | Phase 1 / Phase 2 | 42 | Chinese Academy of Medical SciencesOTHER | 1 | Aug 6, 2018 | clinicaltrials |
| NCT03607643 | A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies | unknown | Phase 1 / Phase 2 | 160 | Leaf Vertical Inc.INDUSTRY | 1 | Jul 31, 2018 | clinicaltrials |
| NCT03601598 | A Trial of SHR-1210 in Combination With SHR6390 in Patients With Advanced CRC, NSCLC and HCC | unknown | Phase 1 / Phase 2 | 41 | Harbin Medical UniversityOTHER | 0 | Jul 26, 2018 | clinicaltrials |
| NCT02062749 | Escalating Doses of Oxaliplatin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Children and Adolescents With Extensive Colon Carcinoma | completed | Phase 1 | 1 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 19, 2018 | clinicaltrials |
| NCT01705002 | Intravenously Administered Pegylated Liposomal Mitomycin-C Lipid-based Prodrug (PROMITIL) in Cancer Patients With Solid Tumors. | completed | Phase 1 | 88 | Lipomedix Pharmaceuticals Inc.INDUSTRY | 1 | Jul 10, 2018 | clinicaltrials |
| NCT02835833 | Study of Nintedanib Plus Bevacizumab in Advanced Solid Tumors | completed | Phase 1 | 21 | University of Alabama at BirminghamOTHER | 1 | Jul 10, 2018 | clinicaltrials |
| NCT01197664 | Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer That Can Be Removed in Surgery | terminated | Phase 1 | 2 | Wake Forest University Health SciencesOTHER | 1 | Jul 2, 2018 | clinicaltrials |
| NCT02423954 | Study of Nivolumab Plus Chemotherapy in Patients With Advanced Cancer (NivoPlus)(NivoPlus) | terminated | Phase 1 / Phase 2 | 33 | Western Regional Medical CenterOTHER | 1 | Jul 2, 2018 | clinicaltrials |
| NCT01048580 | Study of Perifosine + Capecitabine for Colon Cancer Patients | completed | Phase 1 | 10 | AEterna ZentarisINDUSTRY | 0 | Jun 28, 2018 | clinicaltrials |
| NCT03542799 | EGFR-IL12-CART Cells for Patients With Metastatic Colorectal Cancer(EGFRCART) | unknown | Phase 1 | 20 | Shenzhen Second People's HospitalOTHER | 1 | May 31, 2018 | clinicaltrials |
| NCT00827580 | Eniluracil Hand Foot Syndrome | terminated | Phase 1 | 3 | West Virginia UniversityOTHER | 1 | May 30, 2018 | clinicaltrials |
| NCT00003344 | Radiation Therapy Plus Irinotecan in Treating Patients With Colon Cancer | completed | Phase 1 / Phase 2 | 49 | Medical University of South CarolinaOTHER | 1 | May 16, 2018 | clinicaltrials |
| NCT03253185 | A Study of SC-007 in Subjects With Advanced Cancer | terminated | Phase 1 | 7 | AbbVieINDUSTRY | 1 | Apr 27, 2018 | clinicaltrials |
| NCT00149396 | Safety & Efficacy of NV1020 in Colorectal Cancer Metastatic to the Liver | completed | Phase 1 / Phase 2 | 32 | MediGeneINDUSTRY | 1 | Apr 24, 2018 | clinicaltrials |
| NCT01975454 | Study of TLBZT Based Herbal Therapy Plus Chemotherapy for Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 62 | Shanghai University of Traditional Chinese MedicineOTHER | 1 | Apr 19, 2018 | clinicaltrials |
| NCT02577588 | Trial of Adoptive T Cell Therapy With Activated P53 Specific T Cells for Treatment of Advanced Colorectal Cancer(ATACC) | terminated | Phase 1 | 1 | National Center for Tumor Diseases, HeidelbergOTHER | 1 | Apr 11, 2018 | clinicaltrials |
| NCT01520389 | Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment | completed | Phase 1 | 112 | Merrimack PharmaceuticalsINDUSTRY | 1 | Mar 21, 2018 | clinicaltrials |
| NCT01923116 | Therapeutic HPV-16 Vaccination for the Treatment of Anal Dysplasia(VACCAIN-T) | completed | Phase 1 / Phase 2 | 40 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Mar 15, 2018 | clinicaltrials |
| NCT03307603 | Yttrium-90 Radioembolization + Nivolumab for Liver + Extra-hepatic Metastases From Colorectal Cancer | withdrawn | Phase 1 / Phase 2 | 0 | Case Comprehensive Cancer CenterOTHER | 0 | Feb 27, 2018 | clinicaltrials |
| NCT02110953 | Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal Cancer That Has Spread to the Liver | terminated | Phase 1 | 2 | Fox Chase Cancer CenterOTHER | 1 | Feb 26, 2018 | clinicaltrials |
| NCT03435666 | A Bioequivalence Study of Capecitabine Tablets 500 mg in Adult Cancer Patients Under Fed Condition(Capecitabine) | unknown | Phase 1 | 45 | Qilu Pharmaceutical Co., Ltd.INDUSTRY | 0 | Feb 19, 2018 | clinicaltrials |
| NCT01460134 | A Study of CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic Cancers | completed | Phase 1 | 90 | Celldex TherapeuticsINDUSTRY | 1 | Jan 31, 2018 | clinicaltrials |
| NCT01843725 | Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancers(MOMENTUM1) | completed | Phase 1 | 37 | Jules Bordet InstituteOTHER | 1 | Jan 31, 2018 | clinicaltrials |
| NCT01519817 | Cancer Vaccine Targeting Brachyury Protein in Tumors | completed | Phase 1 | 34 | National Cancer Institute (NCI)NIH | 1 | Jan 29, 2018 | clinicaltrials |
| NCT02041481 | MEK Inhibitor MEK162 in Combination With Leucovorin Calcium, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Metastatic Colorectal Cancer | completed | Phase 1 | 26 | City of Hope Medical CenterOTHER | 1 | Jan 25, 2018 | clinicaltrials |
| NCT01012362 | Study of Pazopanib and Ixabepilone in Patients With Solid Tumors | terminated | Phase 1 | 31 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Dec 28, 2017 | clinicaltrials |
| NCT00536809 | Phase I/II Study of Lapatinib in Combination With Oxaliplatin and Capecitabine in Subjects With Advanced Colorectal Cancer | completed | Phase 1 | 12 | GlaxoSmithKlineINDUSTRY | 1 | Dec 18, 2017 | clinicaltrials |
| NCT00226941 | A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer | terminated | Phase 1 / Phase 2 | 23 | George Albert FisherOTHER | 1 | Dec 8, 2017 | clinicaltrials |
| NCT00622674 | Bortezomib and Cetuximab in Treating Patients With Advanced Solid Tumors | completed | Phase 1 | 37 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Dec 2, 2017 | clinicaltrials |
| NCT00540943 | Study of Pazopanib, Irinotecan and Cetuximab in Combination to Treat 2nd Line Metastatic Colorectal Cancer | completed | Phase 1 | 25 | GlaxoSmithKlineINDUSTRY | 1 | Nov 29, 2017 | clinicaltrials |
| NCT00620295 | Bortezomib and Gemcitabine in Treating Older Patients With Advanced Solid Tumors | completed | Phase 1 | 17 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Nov 29, 2017 | clinicaltrials |
| NCT00703638 | Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors | completed | Phase 1 | 16 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Nov 29, 2017 | clinicaltrials |
| NCT01589419 | A Clinical Study Conducted in Multiple Centers Evaluating Escalating Doses of Veliparib in Combination With Capecitabine and Radiation in Patients With Locally Advanced Rectal Cancer | completed | Phase 1 | 32 | AbbVie (prior sponsor, Abbott)INDUSTRY | 2 | Nov 20, 2017 | clinicaltrials |
| NCT02009631 | A Study to Evaluate the Effects of Veliparib on Heart Rhythms in Patients With Solid Tumors | completed | Phase 1 | 45 | AbbVieINDUSTRY | 3 | Nov 20, 2017 | clinicaltrials |
| NCT00387387 | Study On Pazopanib When Given With FOLFOX6 (Fluorouracil, Oxaliplatin, Leucovorin) Or CapeOx (Capecitabine, Oxaliplatin) | completed | Phase 1 | 50 | GlaxoSmithKlineINDUSTRY | 2 | Nov 17, 2017 | clinicaltrials |
| NCT01172860 | Endoscopic Treatment of Inoperable Colorectal Cancer With the EndoVe System(CCEE EndoVe) | completed | Phase 1 | 10 | Mercy University Hospital, Cork, IrelandOTHER | 1 | Nov 9, 2017 | clinicaltrials |
| NCT00647153 | Immunoscintigraphy Using Radiolabeled Monoclonal Antibody in Finding Tumor Cells in Patients With Colorectal Cancer | completed | Phase 1 | 1 | City of Hope Medical CenterOTHER | 1 | Nov 6, 2017 | clinicaltrials |
Data updated 24 days agoSource updated Nov 7, 2018source: clinicaltrials