Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00153816 | Vitamin D/Calcium Polyp Prevention Study | completed | Phase 2 / Phase 3 | 2,813 | Dartmouth-Hitchcock Medical CenterOTHER | 2 | Mar 15, 2017 | clinicaltrials |
| NCT01289821 | First Line Treatment of Metastatic Colorectal Cancer With mFOLFOX6 in Combination With Regorafenib | completed | Phase 2 | 54 | BayerINDUSTRY | 7 | Mar 15, 2017 | clinicaltrials |
| NCT01060007 |
| Five Fractions of Radiotherapy Followed by Full Dose FOLFOX Chemotherapy as Preoperative Treatment for Rectal Cancer |
| completed |
| Phase 2 |
| 80 |
| Washington University School of MedicineOTHER |
| 1 |
| Mar 8, 2017 |
| clinicaltrials |
| NCT01150877 | High Dose Vitamin D Study | completed | Phase 1 / Phase 2 | 40 | University of British ColumbiaOTHER | 1 | Mar 3, 2017 | clinicaltrials |
| NCT02526134 | Placing Trust in Endoscopic Ultrasonography: Impact on Planning Conformal Radiotherapy of Cancer of the Esophagus and Rectum(FIDUCOR) | completed | Phase 2 | 29 | Institut Paoli-CalmettesOTHER | 1 | Mar 3, 2017 | clinicaltrials |
| NCT01802684 | OPTIMOX-aflibercept as First-line Therapy in Patients With Unresectable Metastatic Colorectal Cancer(VELVET) | completed | Phase 2 | 49 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Mar 1, 2017 | clinicaltrials |
| NCT00303875 | Exercise and Dietary Counseling in Improving Physical Activity, Nutrition, and Quality of Life in Older Long-Term Cancer Survivors Who Are Overweight | completed | Phase 2 | 641 | Duke UniversityOTHER | 1 | Feb 23, 2017 | clinicaltrials |
| NCT00335504 | Atorvastatin Calcium, Oligofructose-Enriched Inulin, or Sulindac in Preventing Cancer in Patients at Increased Risk of Developing Colorectal Neoplasia | completed | Phase 2 | 85 | National Cancer Institute (NCI)NIH | 1 | Feb 15, 2017 | clinicaltrials |
| NCT01749956 | 5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer | completed | Phase 2 | 39 | SCRI Development Innovations, LLCOTHER | 1 | Feb 7, 2017 | clinicaltrials |
| NCT00203411 | Bevacizumab Plus Capecitabine (Xeloda) in Patients With Untreated Metastatic Colorectal Cancer | completed | Phase 2 | 45 | Translational Oncology Research InternationalOTHER | 1 | Feb 6, 2017 | clinicaltrials |
| NCT00056030 | Combination Chemotherapy Plus Cetuximab in Treating Patients With Liver Metastases From Colorectal Cancer | completed | Phase 2 | 73 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jan 24, 2017 | clinicaltrials |
| NCT01507103 | Tecemotide (L-BLP25) in Rectal Cancer(SPRINT) | completed | Phase 2 | 124 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 1 | Jan 13, 2017 | clinicaltrials |
| NCT02694718 | A Study of Capecitabine Plus Oxaliplatin in Combination With Pre-operative Pelvic Radiotherapy in Rectal Cancer | completed | Phase 2 | 60 | Hoffmann-La RocheINDUSTRY | 1 | Jan 11, 2017 | clinicaltrials |
| NCT02236884 | The Feasibility and Safety of No-scar Transanal Total Mesorectal Excision for Rectal Cancer | completed | Phase 1 / Phase 2 | 20 | Sun Yat-sen UniversityOTHER | 1 | Dec 19, 2016 | clinicaltrials |
| NCT00016952 | Irinotecan or Fluorouracil Plus Leucovorin in Treating Patients With Previously Treated Metastatic Colorectal Cancer | completed | Phase 2 | 19 | Alliance for Clinical Trials in OncologyOTHER | 2 | Dec 7, 2016 | clinicaltrials |
| NCT00080951 | Irinotecan, Fluorouracil, Leucovorin, and Oxaliplatin as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 14 | Alliance for Clinical Trials in OncologyOTHER | 0 | Dec 7, 2016 | clinicaltrials |
| NCT02077777 | Chemopreventive Action of Mesalazine on Colorectal Cancer: a Pilot Study for an "in Vivo" Evaluation of the Molecular Effects on β-catenin Signaling Pathway. | completed | Phase 2 | 21 | SOFAR S.p.A.INDUSTRY | 1 | Dec 2, 2016 | clinicaltrials |
| NCT01450319 | Cetuximab in Refractory Colorectal Cancer With K-RAS Mutated and Favorable FcγRIIa (CD32) Genotype(MUTEX) | completed | Phase 2 | 73 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 1 | Nov 28, 2016 | clinicaltrials |
| NCT01549535 | Polyp Detection With The Peerscope System™ | completed | Phase 2 | 197 | PeerMedical Ltd.INDUSTRY | 3 | Nov 25, 2016 | clinicaltrials |
| NCT00362102 | A Phase II Study of Cetuximab Plus Irinotecan in Patients With EGFR-detectable Metastatic Colorectal Carcinoma | completed | Phase 2 | 38 | Eli Lilly and CompanyINDUSTRY | 0 | Nov 22, 2016 | clinicaltrials |
| NCT00912743 | Efficacy and Safety of Olaparib in Pretreated Patients With Measurable Colorectal Cancer, Stratified by Microsatellite Instability (MSI) Status | completed | Phase 2 | 33 | AstraZenecaINDUSTRY | 1 | Nov 9, 2016 | clinicaltrials |
| NCT00527111 | Pre-op Rectal ChemoRad +/- Cetuximab | completed | Phase 2 | 139 | US Oncology ResearchINDUSTRY | 1 | Nov 3, 2016 | clinicaltrials |
| NCT00048126 | A Study of Xeloda (Capecitabine) in Patients With Advanced and/or Metastatic Colorectal Cancer | completed | Phase 2 | 57 | Hoffmann-La RocheINDUSTRY | 1 | Nov 2, 2016 | clinicaltrials |
| NCT00048139 | A Study of Xeloda (Capecitabine) in Patients With Advanced and/or Metastatic Colorectal Cancer | completed | Phase 2 | 52 | Hoffmann-La RocheINDUSTRY | 1 | Nov 2, 2016 | clinicaltrials |
| NCT00700570 | A Study of Avastin (Bevacizumab) in Combination With XELOX in Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 45 | Hoffmann-La RocheINDUSTRY | 1 | Nov 2, 2016 | clinicaltrials |
| NCT00778102 | A Study of Avastin (Bevacizumab) in Combination With mFOLFOX-6 or FOLFOXIRI in Patients With Metastatic Colorectal Cancer. | completed | Phase 2 | 80 | Hoffmann-La RocheINDUSTRY | 4 | Nov 2, 2016 | clinicaltrials |
| NCT00940303 | OPAL Study: A Study of Avastin (Bevacizumab) in Combination With FOLFOXIRI in Patients With Previously Untreated Metastatic Colorectal Cancer | completed | Phase 2 | 97 | Hoffmann-La RocheINDUSTRY | 1 | Nov 2, 2016 | clinicaltrials |
| NCT01652482 | Safety and Efficacy Study of MEHD7945A + FOLFIRI Versus Cetuximab + FOLFIRI as Second Line Therapy in Participants With KRAS Wild-Type Metastatic Colorectal Cancer (mCRC) | completed | Phase 2 | 135 | Genentech, Inc.INDUSTRY | 10 | Nov 2, 2016 | clinicaltrials |
| NCT00813605 | QUILT-2.018: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal Carcinoma | completed | Phase 2 | 155 | NantCell, Inc.INDUSTRY | 10 | Oct 27, 2016 | clinicaltrials |
| NCT01043484 | Safety and Efficacy Study to Compare Capecitabine + Bevacizumab Versus Capecitabine, Concomitantly With Radiotherapy as Neoadjuvant Treatment for Patients With Localized and Resectable Rectal Cancer(AVAXEL) | completed | Phase 2 | 90 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Oct 19, 2016 | clinicaltrials |
| NCT01569984 | Radiosensitization of AVASTIN® (Bevacizumab) With Stereotactic Body Radiotherapy for Colorectal Liver Metastasis(SBRT-Avastin) | completed | Phase 2 | 11 | Dr. Yoo-Joung KoOTHER | 1 | Oct 13, 2016 | clinicaltrials |
| NCT00454116 | A Phase II, Double Blind Study of 2 Doses of ZACTIMA™(ZD6474) in Combination With FOLFIRI vs FOLFIRI Alone for the Treatment of Colorectal Cancer in Patients | completed | Phase 2 | 106 | Genzyme, a Sanofi CompanyINDUSTRY | 6 | Oct 7, 2016 | clinicaltrials |
| NCT00278694 | Oxaliplatin and 5-FU Based Preoperative Chemoradiation(LARC-RRP) | completed | Phase 2 | 109 | Oslo University HospitalOTHER | 1 | Sep 29, 2016 | clinicaltrials |
| NCT01263171 | Oxaliplatin, Leucovorin, and Fluorouracil Before and After Radiation Therapy and Surgery in Treating Patients With Rectal Cancer That Can Be Removed by Surgery(COPERNICUS) | completed | Phase 2 | 60 | Cardiff UniversityOTHER | 1 | Sep 21, 2016 | clinicaltrials |
| NCT01269229 | A Trial of Neoadjuvant FOLFOX6 With Short Course Radiotherapy in Patients With Unresectable Rectal Cancer and Liver Metastasis | completed | Phase 2 | 32 | Yonsei UniversityOTHER | 1 | Sep 7, 2016 | clinicaltrials |
| NCT01399684 | A Study Evaluating the Efficacy and Safety of MEGF0444A Dosed to Progression in Combination With Bevacizumab and mFOLFOX-6 in Participants With Previously Untreated Metastatic Colorectal Cancer | completed | Phase 2 | 127 | Genentech, Inc.INDUSTRY | 5 | Aug 26, 2016 | clinicaltrials |
| NCT00796718 | A Study of Xeloda (Capecitabine) Plus Radiotherapy in Participants With Locally Advanced Rectal Cancer | completed | Phase 2 | 62 | Hoffmann-La RocheINDUSTRY | 1 | Aug 25, 2016 | clinicaltrials |
| NCT01344538 | Ginger for Colorectal Cancer Prevention | completed | Phase 2 | 30 | University of MichiganOTHER | 1 | Aug 11, 2016 | clinicaltrials |
| NCT01374425 | Study of Bevacizumab + mFOLFOX6 Versus Bevacizumab + FOLFIRI With Biomarker Stratification in Participants With Previously Untreated Metastatic Colorectal Cancer (mCRC)(MAVERICC) | completed | Phase 2 | 376 | Genentech, Inc.INDUSTRY | 7 | Aug 11, 2016 | clinicaltrials |
| NCT00588640 | Study of D-Methadone in Patients With Chronic Pain | completed | Phase 1 / Phase 2 | 10 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Aug 10, 2016 | clinicaltrials |
| NCT01696630 | Xenon Combined With Intraoperative Thoracic Epidural Analgesia | completed | Phase 2 | 31 | Centre Leon BerardOTHER | 1 | Aug 4, 2016 | clinicaltrials |
| NCT00033748 | Vaccine Therapy in Treating Patients With Colorectal Cancer Metastatic to the Liver | completed | Phase 2 | 56 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jul 19, 2016 | clinicaltrials |
| NCT00336856 | Irinotecan and Cetuximab for Colorectal Cancer as Second Line Therapy | completed | Phase 2 | 35 | University of PittsburghOTHER | 1 | Jul 12, 2016 | clinicaltrials |
| NCT00003834 | Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer | completed | Phase 2 | 44 | Alliance for Clinical Trials in OncologyOTHER | 2 | Jul 6, 2016 | clinicaltrials |
| NCT00023751 | Surgery With or Without Chemotherapy and Radiation Therapy in TreatingPatients With Stage I Rectal Cancer | completed | Phase 2 | 320 | Alliance for Clinical Trials in OncologyOTHER | 3 | Jul 6, 2016 | clinicaltrials |
| NCT00063960 | Hepatic Arterial Infusion With Floxuridine and Systemic Irinotecan After Surgery in Treating Patients With Hepatic (Liver) Metastases From Colorectal Cancer | completed | Phase 2 | 94 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jul 6, 2016 | clinicaltrials |
| NCT00311610 | Liposomal SN-38 in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 30 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jun 29, 2016 | clinicaltrials |
| NCT01086267 | Safety and Efficacy Study of BMS-908662 Alone or in Combination With Cetuximab in Subjects With K-RAS or B-RAF Mutation Positive Advanced or Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 17 | Bristol-Myers SquibbINDUSTRY | 2 | Jun 27, 2016 | clinicaltrials |
| NCT00851084 | Study of Aflibercept And Modified FOLFOX6 As First-Line Treatment In Patients With Metastatic Colorectal Cancer(AFFIRM) | completed | Phase 2 | 268 | SanofiINDUSTRY | 7 | Jun 7, 2016 | clinicaltrials |
| NCT00931203 | Trial of Celecoxib With Preoperative Chemo- Radiation for Locally Advanced Rectal Cancer | completed | Phase 2 | 55 | National Health Research Institutes, TaiwanOTHER | 1 | May 4, 2016 | clinicaltrials |
Data updated 23 days agoSource updated Mar 15, 2017source: clinicaltrials