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Hematopoietic and Lymphoid Cell Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Morphology
Hematopoietic and Lymphoid Cell Neoplasm

Cancer Family

Hematopoietic and Lymphoid Cell Neoplasm

CI-CAN-00000023Explore in graph →

HematologicNon-malignant4,231 active trials98 approved drugs1,009 evidence items

NCIt: C27134
DOID: 2531
MeSH: D019337

Overview
Statistics
Survival
Genomics60
Variants & evidence1009
Drugs99
Trials18680
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (735)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 526–550 of 735 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. A unique cytogenetic-clinicopathological association.
· N Engl J Med · 1983 · PMID 6577285 · validated civic_curation pubmed
Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt.
· Blood · 1992 · PMID 1391946 · validated civic_curation pubmed
Distinctive immunophenotypic features of t(8;21)(q22;q22) acute myeloblastic leukemia in children.
· Blood · 1992 · PMID 1467524 · validated civic_curation pubmed
Morphological subtyping of acute myeloid leukemia with maturation (AML-M2): homogeneous pink-colored cytoplasm of mature neutrophils is most characteristic of AML-M2 with t(8;21).
· Leukemia · 1997 · PMID 9180287 · validated civic_curation pubmed
Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact.
· Blood · 2019 · PMID 30602617 · validated civic_curation pubmed
Chromosomal abnormalities identify high-risk and low-risk patients with acute lymphoblastic leukemia.
· Blood · 1986 · PMID 3455828 · validated civic_curation pubmed
A novel specific signature of pediatric MOZ-CBP acute myeloid leukemia.
· Leuk Res · 2010 · PMID 20630590 · validated

Showing 526–550 of 735 publications

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civic_curation

TCF3 gene rearrangements in pediatric B-cell acute lymphoblastic leukemia-A single center experience.

· Int J Lab Hematol · 2023 · PMID 37058324 · validated civic_curation pubmed

B-ALL With t(5;14)(q31;q32); IGH-IL3 Rearrangement and Eosinophilia: A Comprehensive Analysis of a Peculiar IGH-Rearranged B-ALL.

· Front Oncol · 2019 · PMID 31921638 · validated civic_curation pubmed

Experience with provisional WHO-entities large B-cell lymphoma with IRF4-rearrangement and Burkitt-like lymphoma with 11q aberration in paediatric patients of the NHL-BFM group.

· Br J Haematol · 2020 · PMID 32239695 · validated civic_curation pubmed

3q26.2/MECOM Rearrangements by Pericentric Inv(3): Diagnostic Challenges and Clinicopathologic Features.

· Cancers (Basel) · 2023 · PMID 36672407 · validated civic_curation pubmed

Complex chromosomal rearrangements leading to MECOM overexpression are recurrent in myeloid malignancies with various 3q abnormalities.

· Genes Chromosomes Cancer · 2016 · PMID 26815134 · validated civic_curation pubmed

Atypical 3q26/MECOM rearrangements genocopy inv(3)/t(3;3) in acute myeloid leukemia.

· Blood · 2020 · PMID 32219447 · validated civic_curation pubmed

Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.

· N Engl J Med · 2012 · PMID 22417203 · validated civic_curation pubmed

Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients.

· Blood · 2014 · PMID 24797300 · validated civic_curation pubmed

Minimal residual disease levels assessed by NPM1 mutation-specific RQ-PCR provide important prognostic information in AML.

· Blood · 2009 · PMID 19587375 · validated civic_curation pubmed

Wilms tumor 1 gene mutations are associated with a higher risk of recurrence in young adults with acute myeloid leukemia: a study from the Acute Leukemia French Association.

· Cancer · 2009 · PMID 19536888 · validated civic_curation pubmed

Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study.

· Leukemia · 2010 · PMID 20376086 · validated civic_curation pubmed

Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor.

· J Clin Oncol · 2010 · PMID 20368538 · validated civic_curation pubmed

Potential application of IDH1 and IDH2 mutations as prognostic indicators in non-promyelocytic acute myeloid leukemia: a meta-analysis.

· Leuk Lymphoma · 2012 · PMID 22616558 · validated civic_curation pubmed

IDH1 and IDH2 mutation analysis in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome.

· Ann Hematol · 2012 · PMID 21997850 · validated civic_curation pubmed

U2AF1 mutations in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome.

· PLoS One · 2012 · PMID 23029227 · validated civic_curation pubmed

Phase II study of the oral MEK inhibitor selumetinib in advanced acute myelogenous leukemia: a University of Chicago phase II consortium trial.

· Clin Cancer Res · 2014 · PMID 24178622 · validated civic_curation pubmed

Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions.

· Blood · 2004 · PMID 14726385 · validated civic_curation pubmed

Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma.

· Blood · 2012 · PMID 22383795 · validated civic_curation pubmed