Cancer Family
Esophageal Neoplasm
CI-CAN-00000174Explore in graph →
Non-malignant555 active trials6 approved drugs12 evidence items
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Cancer Family
CI-CAN-00000174Explore in graph →
Clinical trials
2,208 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02954536 | Phase II Trial of Pembrolizumab With Trastuzumab and Chemotherapy in Advanced HER2 Positive Esophagogastric (EG) Cancer | completed | Phase 2 | 37 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 16, 2023 | clinicaltrials |
| NCT04837677 | A Study of PRT1419 in Patients With Advanced Solid Tumors | completed | Phase 1 | 26 | Prelude TherapeuticsINDUSTRY | 1 | Mar 15, 2023 | clinicaltrials |
| NCT02564263 | Study of Pembrolizumab (MK-3475) Versus Investigator's Choice Standard Therapy for Participants With Advanced Esophageal/ Esophagogastric Junction Carcinoma That Progressed After First-Line Therapy (MK-3475-181/KEYNOTE-181) | completed | Phase 3 | 628 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Mar 13, 2023 | clinicaltrials |
| NCT05740852 | Analysis of Risk Factors of Postoperative Pulmonary Infection in Patients With Esophageal Cancer | completed | — | 1,688 | Xijing HospitalOTHER | 0 | Feb 23, 2023 | clinicaltrials |
| NCT01973725 | Study of Icotinib Hydrochloride in Treating Patients With Recurrent or Metastatic Esophageal Cancer After Failure of Conventional Chemotherapy | completed | Phase 2 | 50 | Yuhong LiOTHER | 1 | Feb 17, 2023 | clinicaltrials |
| NCT02976909 | Efficacy and Safety of TPF Induction Chemotherapy for Borderline-resectable Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 46 | Yuhong LiOTHER | 1 | Feb 17, 2023 | clinicaltrials |
| NCT02023593 | FOLFIRI as Second Line Chemotherapy for Metastatic Esophageal Carcinoma | completed | Phase 2 | 35 | Yuhong LiOTHER | 1 | Feb 16, 2023 | clinicaltrials |
| NCT02350517 | Endostar Combined With Paclitaxel and Nedaplatin in Treating Patients With Recurrent or Metastatic Esophageal Cancer | completed | Phase 2 | 52 | Yuhong LiOTHER | 1 | Feb 16, 2023 | clinicaltrials |
| NCT02965976 | Botulinum Toxin Type A in Preventing Complications After Surgery in Patients With Esophageal Cancer | completed | Phase 2 | 33 | Roswell Park Cancer InstituteOTHER | 1 | Feb 16, 2023 | clinicaltrials |
| NCT02976896 | Apatinib for Esophageal Squamous Cell Cancer After the Failure of Standard Treatment(Poetry-1) | completed | Phase 2 | 43 | Yuhong LiOTHER | 1 | Feb 16, 2023 | clinicaltrials |
| NCT04199832 | To Compare the Effect of Different Nutritional Pathways on Improving Nutritional Status of Esophageal Cancer Patients Undergoing Chemoradiotherapy | completed | — | 156 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Feb 16, 2023 | clinicaltrials |
| NCT04764643 | The Efficacy of N-acetylcysteine on Alleviating Symptom Caused by Lugol Chromoendoscopy | completed | N/A | 140 | Xijing Hospital of Digestive DiseasesOTHER | 1 | Jan 30, 2023 | clinicaltrials |
| NCT04293458 | Efficacy of EsoGuard on Samples Collected Using EsoCheck Versus EGD for the Diagnosis of BE(ESOGUARDBE1) | completed | N/A | 145 | Lucid Diagnostics, Inc.INDUSTRY | 2 | Jan 25, 2023 | clinicaltrials |
| NCT04046601 | Impedance Spectroscopy in Esophageal Cancer | completed | N/A | 67 | Sana Klinikum OffenbachOTHER | 1 | Jan 17, 2023 | clinicaltrials |
| NCT04380480 | Percutaneous Endoscopic Gastrostomy Before Definitive Concurrent Chemoradiation Therapy for Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 63 | Sun Yat-sen UniversityOTHER | 1 | Jan 11, 2023 | clinicaltrials |
| NCT03160209 | HIV and Other Risk Factors for Esophageal Squamous Cell Carcinoma in Malawi | completed | — | 600 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Jan 6, 2023 | clinicaltrials |
| NCT00586872 | Endoscopic Mucosal Resection (EMR) in Barrett's Esophagus | completed | — | 1,000 | Mayo ClinicOTHER | 1 | Dec 15, 2022 | clinicaltrials |
| NCT03762564 | Study With Paclitaxel +/- Ramucirumab in Patients With Squamous-cell Carcinoma of the Esophagus After Prior Therapy(RAMOS) | completed | Phase 2 | 21 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus NordwestOTHER | 1 | Dec 8, 2022 | clinicaltrials |
| NCT03691090 | Study of SHR-1210 in Combination With Chemotherapy in Advanced Esophageal Cancer | completed | Phase 3 | 596 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Dec 7, 2022 | clinicaltrials |
| NCT03057288 | Prospective Study Evaluating the Feasibility of Fiducial Markers Placement for Patients With Esophageal or Rectal Cancer(FIDECHO) | completed | N/A | 40 | Société Française d'Endoscopie DigestiveOTHER | 1 | Dec 5, 2022 | clinicaltrials |
| NCT05615129 | Sequence and Time-of-day Infusion of immunoCHemotherapy Affect Response in Oesophageal Cancer in the NeOadjuvant Setting(RICE-Chronos) | completed | — | 350 | Guangdong Provincial People's HospitalOTHER | 1 | Nov 29, 2022 | clinicaltrials |
| NCT05628441 | Real-time Computer Aided Detection of Barrett's Neoplasia | completed | — | 30 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Nov 28, 2022 | clinicaltrials |
| NCT02810652 | Perioperative Geriatrics Intervention for Older Cancer Patients Undergoing Surgical Resection | completed | N/A | 160 | Massachusetts General HospitalOTHER | 1 | Nov 22, 2022 | clinicaltrials |
| NCT05318404 | Conventional Oral Intake vs Delayed Oral Intake With Jejunostomy Feeding After Esophagectomy (JNS Study)(JNS) | completed | N/A | 58 | Seoul National University HospitalOTHER | 1 | Nov 9, 2022 | clinicaltrials |
| NCT00911820 | Cisplatin, Irinotecan and Bevacizumab (PCA) Versus Docetaxel, Cisplatin, Irinotecan and Bevacizumab (TPCA) in Metastatic Esophageal and Gastric Cancer | completed | Phase 2 | 88 | Dana-Farber Cancer InstituteOTHER | 1 | Nov 8, 2022 | clinicaltrials |
| NCT05604664 | Clinical Value and Efficacy Index of Lymphadenectomy for Thoracic Escc | completed | — | 1,727 | Yongtao HanOTHER | 1 | Nov 4, 2022 | clinicaltrials |
| NCT05604950 | Surgery Versus Non-surgical Treatment for Esophageal Squamous Cell Carcinoma in Patients Older Than 70 Years | completed | — | 2 | Yongtao HanOTHER | 0 | Nov 3, 2022 | clinicaltrials |
| NCT03660449 | Moderately Hypofractionated Conformal Radiation Combined With S-1 for Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 58 | Sun Yat-sen UniversityOTHER | 1 | Oct 26, 2022 | clinicaltrials |
| NCT04958044 | Endoscopic Assisted Calcium Electroporation in Esophageal Cancer | completed | Phase 1 | 10 | Michael Patrick AchiamOTHER | 1 | Oct 26, 2022 | clinicaltrials |
| NCT00623831 | A Phase 1 Study of Mixed Bacteria Vaccine (MBV) in Patients With Tumors Expressing NY-ESO-1 Antigen | completed | Phase 1 | 17 | Ludwig Institute for Cancer ResearchOTHER | 1 | Oct 25, 2022 | clinicaltrials |
| NCT02489422 | Programs To Support You During Chemotherapy(PRO-YOU) | completed | N/A | 44 | Wake Forest University Health SciencesOTHER | 1 | Oct 14, 2022 | clinicaltrials |
| NCT00199849 | NY-ESO-1 Plasmid DNA (pPJV7611) Cancer Vaccine | completed | Phase 1 | 18 | Ludwig Institute for Cancer ResearchOTHER | 1 | Oct 10, 2022 | clinicaltrials |
| NCT05569668 | Neoadjuvant Chemotherapy Compared With Surgery for Esophageal Carcinoma | completed | — | 826 | Henan Cancer HospitalOTHER_GOV | 1 | Oct 6, 2022 | clinicaltrials |
| NCT02395705 | Neoadjuvant Chemotherapy Versus Surgery Alone for Esophageal Squamous Cell Carcinoma | completed | Phase 3 | 528 | Henan Cancer HospitalOTHER_GOV | 1 | Oct 5, 2022 | clinicaltrials |
| NCT03416244 | A Multicenter Open-label Phase II Trial to Evaluate Nivolumab and Ipilimumab for 2nd Line Therapy in Elderly Patients With Advanced Esophageal Squamous Cell Cancer(RAMONA) | completed | Phase 2 | 66 | AIO-Studien-gGmbHOTHER | 1 | Sep 29, 2022 | clinicaltrials |
| NCT02513784 | Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal Microbiome(Mouthwash) | completed | N/A | 20 | Columbia UniversityOTHER | 1 | Sep 22, 2022 | clinicaltrials |
| NCT04609813 | Esophageal cAncer Screening Trial(EAST) | completed | — | 14,597 | Changhai HospitalOTHER | 1 | Sep 21, 2022 | clinicaltrials |
| NCT02559687 | Study of Pembrolizumab (MK-3475) in Previously-Treated Participants With Advanced Carcinoma of the Esophagus or Esophagogastric Junction (MK-3475-180/KEYNOTE-180) | completed | Phase 2 | 121 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Sep 14, 2022 | clinicaltrials |
| NCT01900691 | Removal of the Evolution® Esophageal Stent - Fully Covered(CLARITY) | completed | N/A | 130 | Cook Group IncorporatedINDUSTRY | 1 | Sep 13, 2022 | clinicaltrials |
| NCT01212822 | Bevacizumab and Combination Chemotherapy Before Surgery in Treating Patients With Locally Advanced Esophageal or Stomach Cancer | completed | Phase 2 | 20 | Fox Chase Cancer CenterOTHER | 1 | Sep 7, 2022 | clinicaltrials |
| NCT03662204 | Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Solid Tumors | completed | — | 5,133 | Exact Sciences CorporationINDUSTRY | 1 | Sep 1, 2022 | clinicaltrials |
| NCT04005170 | Combination of Toripalimab and Chemoradiotherapy in Esophageal Cancer | completed | Phase 2 | 42 | Mian XIOTHER | 1 | Aug 23, 2022 | clinicaltrials |
| NCT05499195 | Adjuvant Radiotherapy for pT1b Esophageal Cancer After Submucosal Endoscopic Resection | completed | — | 159 | Chinese Academy of Medical SciencesOTHER | 1 | Aug 12, 2022 | clinicaltrials |
| NCT01780961 | Esophageal Cancer Tissue Banking(ESBX) | completed | — | 311 | Washington University School of MedicineOTHER | 1 | Aug 9, 2022 | clinicaltrials |
| NCT03925870 | KN046 in Subjects With Late Stage Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 45 | Jiangsu Alphamab Biopharmaceuticals Co., LtdINDUSTRY | 1 | Aug 5, 2022 | clinicaltrials |
| NCT04545632 | Docetaxel Ethanol-induced Symptoms; The Incidence and Risk Forecating Factor(DETECT) | completed | — | 458 | Boryung Pharmaceutical Co., LtdINDUSTRY | 1 | Jul 27, 2022 | clinicaltrials |
| NCT01802203 | trūFreeze® Spray Cryotherapy Patient Registry | completed | — | 275 | US Endoscopy Group Inc.INDUSTRY | 1 | Jul 25, 2022 | clinicaltrials |
| NCT03529669 | Cytosponge™ for Post-Chemoradiation Surveillance of Oesophageal Cancer(CYTOFLOC) | completed | N/A | 41 | University of OxfordOTHER | 1 | Jul 25, 2022 | clinicaltrials |
| NCT04547881 | Gravity Assisted Technique for Esophageal Endoscopic Submucosal Dissection (ESD) | completed | — | 32 | Baylor College of MedicineOTHER | 1 | Jul 21, 2022 | clinicaltrials |
Data updated 23 days agoSource updated Mar 16, 2023source: clinicaltrials