Cancer Family
Esophageal Neoplasm
CI-CAN-00000174Explore in graph →
Non-malignant555 active trials6 approved drugs12 evidence items
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Cancer Family
CI-CAN-00000174Explore in graph →
Clinical trials
2,208 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06668454 | Chemoimmunotherapy Followed by Surgery for Oligometastatic Esophagogastric Cancer: (TORO Protocol)(TORO) | recruiting | N/A | 72 | University Health Network, TorontoOTHER | 1 | May 16, 2025 | clinicaltrials |
| NCT04666090 | Carrelizumab, Chemotherapy and Apatinib in the Neoadjuvant Treatment of Resectable Esophageal Squamous Cell Carcinoma | active not recruiting | Phase 2 | 42 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER |
| 1 |
| May 15, 2025 |
| clinicaltrials |
| NCT06861894 | Active Surveillance After Neoadjuvant Adebrelimab Combined With Chemoradiotherapy for Resectable ESCC | not yet recruiting | Phase 2 | 164 | Zhigang LiOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT02495337 | Tissue Collection Protocol for Gastroesophageal Cancers | recruiting | — | 100 | University Health Network, TorontoOTHER | 1 | May 14, 2025 | clinicaltrials |
| NCT05144698 | RAPA-201 Therapy of Solid Tumors | recruiting | Phase 1 / Phase 2 | 37 | Rapa Therapeutics LLCINDUSTRY | 1 | May 14, 2025 | clinicaltrials |
| NCT06965205 | Use of Different Enteral Feeds to Impact on Chyle Leaks in Oesophagectomy | not yet recruiting | N/A | 160 | Royal College of Surgeons, IrelandOTHER | 0 | May 11, 2025 | clinicaltrials |
| NCT06965829 | The Effect of Neoadjuvant Chemoimmnotherapy Combined With Node Sparing Radiotherapy for cT3N+ EC | not yet recruiting | Phase 2 | 40 | Shanghai Chest HospitalOTHER | 1 | May 11, 2025 | clinicaltrials |
| NCT05179824 | Tempus Priority Study: A Pan-tumor Observational Study | active not recruiting | — | 1,000 | Tempus AIINDUSTRY | 1 | May 6, 2025 | clinicaltrials |
| NCT06169163 | Volatile Organic Compounds as Breath Biomarkers in Squamous Oesophageal Neoplasms(ViSON) | recruiting | — | 518 | Imperial College LondonOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT04734821 | Fluorescence Image Guided Foregut Surgery(FOREGUT) | recruiting | N/A | 60 | IHU StrasbourgOTHER | 1 | May 1, 2025 | clinicaltrials |
| NCT03653052 | Do Changes in ctDNA Predict Response for Patients With Oesophageal Cancer Receiving Durvalumab(CALIBRATION) | active not recruiting | Phase 2 | 18 | Simon C Pacey, MDOTHER | 1 | Apr 24, 2025 | clinicaltrials |
| NCT06822413 | Raman Spectroscopy-Based Deep Learning Model for Early Pan-Cancer Early Diagnosis | recruiting | — | 600 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Apr 24, 2025 | clinicaltrials |
| NCT06908382 | Neoadjuvant QL1706 Therapy for ESCC | recruiting | Phase 2 | 32 | Shandong Provincial HospitalOTHER_GOV | 1 | Apr 18, 2025 | clinicaltrials |
| NCT04996095 | The Registry Study of Genetic Alterations of Esophageal Cancer in Taiwan | active not recruiting | — | 400 | National Health Research Institutes, TaiwanOTHER | 1 | Apr 17, 2025 | clinicaltrials |
| NCT06637163 | Benmelstobart Combined With Radiochemotherapy as Neoadjuvant Treatment Iin ESCC | recruiting | Phase 2 | 100 | Shanghai Zhongshan HospitalOTHER | 1 | Apr 17, 2025 | clinicaltrials |
| NCT06843889 | A Phase II Study of Toripalimab Combined With Sequential Neoadjuvant Chemoradiotherapy in Patients With Esophageal Squamous Cell Carcinoma | recruiting | Phase 2 | 34 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Apr 16, 2025 | clinicaltrials |
| NCT06926374 | Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery | recruiting | N/A | 90 | Chinese University of Hong KongOTHER | 1 | Apr 16, 2025 | clinicaltrials |
| NCT06923020 | Association of Nutritional Status With Immune Checkpoint Inhibitor Efficacy in Metastatic Metastatic Esophagogastric Cancer. | enrolling by invitation | — | 200 | Yongxu JiaOTHER | 1 | Apr 11, 2025 | clinicaltrials |
| NCT04166721 | WaKING: Wnt and checKpoint INhibition in Gastric Cancer | active not recruiting | Phase 1 / Phase 2 | 52 | Royal Marsden NHS Foundation TrustOTHER | 1 | Apr 6, 2025 | clinicaltrials |
| NCT05706025 | Study to Evaluate EnteroTracker® as a Sampling Method to Screen for Barrett's Esophagus/Esophageal Cancer | enrolling by invitation | N/A | 60 | University of Colorado, DenverOTHER | 1 | Apr 6, 2025 | clinicaltrials |
| NCT06907602 | Optimizing Neoadjuvant Treatment Regimens for Locally Advanced Esophageal Squamous Cell Carcinoma(ONTRESCC) | recruiting | Phase 2 / Phase 3 | 120 | Peking Union Medical College HospitalOTHER | 1 | Apr 2, 2025 | clinicaltrials |
| NCT06903871 | Toripalimab Adjuvant Therapy in Subjects With Resected Esophageal Squamous Cell Carcinoma Who Achieved Pathological Complete Response (pCR) | not yet recruiting | Phase 2 | 190 | Hebei Medical University Fourth HospitalOTHER | 1 | Apr 1, 2025 | clinicaltrials |
| NCT06690216 | Evaluation of [18F]AlF-NOTA-PCP2 PET/CT for PD-L1 Detection in Malignant Tumors(PD-L1-PET) | enrolling by invitation | Phase 1 / Phase 2 | 100 | Man HuOTHER | 1 | Mar 30, 2025 | clinicaltrials |
| NCT05804331 | The Australia and New Zealand Multicentre Upper Gastrointestinal Endoscopic Tissue Resection Study(ANZ UGI) | recruiting | — | 500 | Western Sydney Local Health DistrictOTHER | 1 | Mar 27, 2025 | clinicaltrials |
| NCT05473156 | A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies(APT-CUBE) | recruiting | Phase 1 / Phase 2 | 168 | AP Biosciences Inc.INDUSTRY | 1 | Mar 26, 2025 | clinicaltrials |
| NCT06715501 | Efficacy and Safety of Cadonilimab and Chemoradiotherapy in Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma | enrolling by invitation | N/A | 20 | First Affiliated Hospital of Ningbo UniversityNETWORK | 1 | Mar 25, 2025 | clinicaltrials |
| NCT04802876 | Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors(ACROPOLI) | active not recruiting | Phase 2 | 184 | SOLTI Breast Cancer Research GroupOTHER | 1 | Mar 21, 2025 | clinicaltrials |
| NCT06889402 | Prognostic Analysis of Esophageal Cancer with Complete Pathological Response After Neoadjuvant Therapy | not yet recruiting | — | 600 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Mar 21, 2025 | clinicaltrials |
| NCT06879483 | Thoraco-laparoscopic Partial Esophagogastrectomy for Management of Esophageal Cancer | not yet recruiting | N/A | 30 | Sohag UniversityOTHER | 1 | Mar 17, 2025 | clinicaltrials |
| NCT04510129 | A Multicenter Cancer Biospecimen Collection Study | recruiting | — | 1,650 | Cofactor Genomics, Inc.INDUSTRY | 1 | Mar 12, 2025 | clinicaltrials |
| NCT06861777 | Total Neoadjuvant Therapy Combined With Adebrelimab in Locally Advanced Resectable ESCC | not yet recruiting | Phase 2 / Phase 3 | 474 | YIN LIOTHER | 1 | Mar 11, 2025 | clinicaltrials |
| NCT06863831 | A Multicenter Trial of YSQTG vs. Simulated Agents With Neoadjuvant Chemoradiotherapy or Chemoimmunotherapy for EC | enrolling by invitation | N/A | 536 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Mar 7, 2025 | clinicaltrials |
| NCT04460352 | Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer(NEEDS) | recruiting | Phase 3 | 1,020 | Karolinska University HospitalOTHER | 5 | Mar 6, 2025 | clinicaltrials |
| NCT05865743 | Perioperative SDD to Prevent Infectious Complications After Esophagectomy(PERSuaDER) | recruiting | Phase 3 | 854 | Radboud University Medical CenterOTHER | 2 | Mar 5, 2025 | clinicaltrials |
| NCT02634645 | TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus) | recruiting | — | 5,000 | University of Colorado, DenverOTHER | 1 | Feb 28, 2025 | clinicaltrials |
| NCT06692270 | Tislelizumab as Single-Agent Neoadjuvant Immunotherapy in Resectable Esophageal Squamous Cell Carcinoma | not yet recruiting | Phase 2 | 20 | Fujian Cancer HospitalOTHER_GOV | 0 | Feb 28, 2025 | clinicaltrials |
| NCT06852456 | QL1706 in Combination With Neoadjuvant Chemotherapy Versus Neoadjuvant Chemotherapy for Locally Advanced, Resectable Esophageal Squamous Cell Carcinoma | not yet recruiting | Phase 2 | 30 | Qilu Pharmaceutical Co., Ltd.INDUSTRY | 0 | Feb 28, 2025 | clinicaltrials |
| NCT06713421 | Effect of Premedication With Pronase on Mucosal Cleanliness During EGD | recruiting | N/A | 3,000 | Changhai HospitalOTHER | 1 | Feb 25, 2025 | clinicaltrials |
| NCT06833775 | Evaluation of Neoadjuvant Therapy Efficacy and Postoperative Pathological Indicators in Esophageal Cancer Using CT and Multimodal MRI | not yet recruiting | — | 400 | Henan Cancer HospitalOTHER_GOV | 0 | Feb 20, 2025 | clinicaltrials |
| NCT06289374 | Longitudinal Assessment of Biomarkers After Oesophagogastric Cancer Surgery(LABS) | recruiting | — | 100 | Imperial College LondonOTHER | 1 | Feb 19, 2025 | clinicaltrials |
| NCT06829095 | Personalized Nutrition Counseling and Nutritional Status of Esophageal Cancer and HNSCC Patients Undergoing CCRT | recruiting | — | 90 | Chang Gung Memorial HospitalOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT06828718 | The Neoadjuvant Treatment Modalities in Patients With Locally Advanced Esophageal Squamous Cell Carcinoma (NEO-EC)(NEO-EC) | active not recruiting | — | 1,000 | Hebei Medical University Fourth HospitalOTHER | 1 | Feb 14, 2025 | clinicaltrials |
| NCT05491616 | Nivolumab During Active Surveillance After Neoadjuvant Chemoradiation for Esophageal Cancer: SANO-3 Study(SANO-3) | active not recruiting | Phase 2 | 77 | Erasmus Medical CenterOTHER | 1 | Feb 13, 2025 | clinicaltrials |
| NCT02972372 | Chemoradiation Versus Esophagectomy for Locally Advanced Esophageal Cancer(CELAEC) | recruiting | N/A | 196 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Feb 10, 2025 | clinicaltrials |
| NCT06818214 | Mechanistic Study on the Diagnosis of Esophageal Cancer Lymph Node Metastasis Using Spectral CT, Multimodal MRI, FAPI PET-CT, Pathology, and AI Evaluation System | not yet recruiting | — | 400 | Henan Cancer HospitalOTHER_GOV | 0 | Feb 10, 2025 | clinicaltrials |
| NCT05937438 | Postoperative Radiotherapy Followed by Immunotherapy for Locally Advanced Esophageal Carcinoma | recruiting | Phase 1 / Phase 2 | 70 | Anhui Provincial HospitalOTHER_GOV | 1 | Jan 29, 2025 | clinicaltrials |
| NCT06302660 | Profiling Microbiome Associated Metabolic Pathways in Oesophageal Cancer Survivors(MAPLES) | active not recruiting | — | 100 | Imperial College LondonOTHER | 1 | Jan 27, 2025 | clinicaltrials |
| NCT06306755 | Effectiveness of Risk-based Sequential Screening for Esophageal and Gastric Cancer(ERSS-EGC) | recruiting | N/A | 21,000 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jan 24, 2025 | clinicaltrials |
| NCT06790797 | Investigating the Biomarkers in Tumor and Peripheral Blood to Evaluate the Efficacy of Cancer Immunotherapy in Chest Cancer Patients | recruiting | — | 50 | Zhao JunOTHER | 1 | Jan 24, 2025 | clinicaltrials |
| NCT06489197 | AK112 Combined With Chemotherapy as the First-line Treatment in Advanced Esophageal Squamous Cell Carcinoma Patients | recruiting | Phase 2 | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jan 22, 2025 | clinicaltrials |
Data updated 23 days agoSource updated May 16, 2025source: clinicaltrials