Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,058 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00045968 | Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer(GBM) | unknown | Phase 3 | 348 | Northwest BiotherapeuticsINDUSTRY | 4 | May 18, 2022 | clinicaltrials |
| NCT05334238 | Orelabrutinib Maintenance Therapy After ASCT in Primary Central Nervous System Lymphoma | unknown | Phase 3 | 174 | Ruijin HospitalOTHER | 1 | Apr 19, 2022 | clinicaltrials |
| NCT02419664 | Ga-68-DOTATOC -PET in the Management of Pituitary Tumours | terminated | Phase 3 | 22 | Göteborg UniversityOTHER | 1 | Mar 31, 2022 | clinicaltrials |
| NCT01951469 | Gefitinib With or Without Chemotherapy in Brain Metastases From Non-small Cell Lung Cancer | unknown | Phase 3 | 160 | Sun Yat-sen UniversityOTHER | 1 | Mar 8, 2022 | clinicaltrials |
| NCT02313389 | Maintenance Treatment Versus Observation in Elderly Patients With PCNS Lymphoma(BLOCAGE-01) | unknown | Phase 3 | 428 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Mar 2, 2022 | clinicaltrials |
| NCT03763422 | Trial in Low Grade Glioma Patients: Wait or Treat(IWOT) | terminated | Phase 3 | 19 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 10 | Feb 1, 2022 | clinicaltrials |
| NCT02796261 | Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients(STELLAR) | unknown | Phase 3 | 343 | Orbus Therapeutics, Inc.INDUSTRY | 8 | Jan 21, 2022 | clinicaltrials |
| NCT02892708 | Impact of Surgery on the Treatment of Supratentorial Malignant Gliomas in Subjects Aged 70 and Over(CSA) | completed | Phase 3 | 107 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Dec 9, 2021 | clinicaltrials |
| NCT00369785 | Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors | completed | Phase 3 | 198 | Wake Forest University Health SciencesOTHER | 1 | Oct 20, 2021 | clinicaltrials |
| NCT01479686 | iMRI Guided Resection in Cerebral Glioma Surgery | completed | Phase 3 | 321 | Huashan HospitalOTHER | 1 | Oct 19, 2021 | clinicaltrials |
| NCT05080010 | Adjuvant Chemotherapy for High-risk Postenucleation Retinoblastoma | recruiting | Phase 3 | 500 | Sun Yat-sen UniversityOTHER | 1 | Oct 15, 2021 | clinicaltrials |
| NCT05054426 | Intermediate Dose of IV MTX as CNS Prophylaxis for High Risk DLBCL(NHL-011) | unknown | Phase 3 | 488 | Peking Union Medical College HospitalOTHER | 1 | Sep 23, 2021 | clinicaltrials |
| NCT04277403 | HA-WBRT vs SRS in Patients With Multiple Brain Metastases(HipSter) | unknown | Phase 3 | 150 | Medical University InnsbruckOTHER | 1 | Sep 5, 2021 | clinicaltrials |
| NCT03393000 | Safety and Efficacy Study of Trans Sodium Crocetinate (TSC) in Newly Diagnosed Glioblastoma (GBM) Biopsy-Only Subjects(INTACT) | terminated | Phase 3 | 19 | Diffusion Pharmaceuticals IncINDUSTRY | 1 | Jul 22, 2021 | clinicaltrials |
| NCT03008148 | Phase II/III Trial of CCRT With or Without JP001 for Newly Diagnosed GBM | unknown | Phase 2 / Phase 3 | 288 | Johnpro Biotech, Inc.INDUSTRY | 1 | May 11, 2021 | clinicaltrials |
| NCT03025893 | A Phase II/III Study of High-dose, Intermittent Sunitinib in Patients With Recurrent Glioblastoma Multiforme(STELLAR) | unknown | Phase 2 / Phase 3 | 100 | Amsterdam UMC, location VUmcOTHER | 1 | Apr 19, 2021 | clinicaltrials |
| NCT03419403 | UNITE Study: Understanding New Interventions With GBM ThErapy | terminated | Phase 3 | 40 | AbbVieINDUSTRY | 5 | Apr 14, 2021 | clinicaltrials |
| NCT04829097 | Neoadjuvant Temozolomide Combined With Simultaneous IMRT for Treatment of Glioblastoma | unknown | Phase 3 | 80 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolOTHER | 1 | Apr 2, 2021 | clinicaltrials |
| NCT02678975 | Disulfiram in Recurrent Glioblastoma | completed | Phase 2 / Phase 3 | 88 | Sahlgrenska University HospitalOTHER | 2 | Mar 18, 2021 | clinicaltrials |
| NCT04799002 | Topotecan and Melphalan for Retinoblastoma | recruiting | Phase 3 | 50 | Sun Yat-sen UniversityOTHER | 1 | Mar 16, 2021 | clinicaltrials |
| NCT01290939 | Bevacizumab and Lomustine for Recurrent GBM | completed | Phase 3 | 592 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 1 | Feb 15, 2021 | clinicaltrials |
| NCT00033254 | Radiation Therapy With or Without Thalidomide in Treating Patients With Brain Metastases | completed | Phase 3 | 332 | National Cancer Institute (NCI)NIH | 1 | Oct 30, 2020 | clinicaltrials |
| NCT01987596 | Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer | terminated | Phase 3 | 23 | Barbara Ann Karmanos Cancer InstituteOTHER | 1 | Oct 29, 2020 | clinicaltrials |
| NCT00418691 | Effects of Methylphenidate Versus Sustained Release Methylphenidate on Cognitive Functioning | terminated | Phase 3 | 34 | M.D. Anderson Cancer CenterOTHER | 1 | Sep 23, 2020 | clinicaltrials |
| NCT02657785 | Treatment of PCNSL With R-IDARAM and Intrathecal Immunochemotherapy | recruiting | Phase 2 / Phase 3 | 100 | Navy General Hospital, BeijingOTHER | 1 | Sep 9, 2020 | clinicaltrials |
| NCT02836158 | Therapeutic Effects of R-IDARAM and Intrathecal Immunochemotherapy on Elderly Patients With PCNSL | recruiting | Phase 2 / Phase 3 | 100 | Navy General Hospital, BeijingOTHER | 1 | Sep 9, 2020 | clinicaltrials |
| NCT04536649 | Proton and Heavy Ion Beam Radiation vs. Photon Beam Radiation for Newly Diagnosed Glioblastoma. | unknown | Phase 3 | 369 | Shanghai Proton and Heavy Ion CenterOTHER | 1 | Sep 2, 2020 | clinicaltrials |
| NCT03558516 | Magnesium and Intraoperative Blood Loss in Meningioma Surgery | completed | Phase 3 | 80 | Mahidol UniversityOTHER | 1 | Jul 13, 2020 | clinicaltrials |
| NCT01649830 | Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade Glioma | unknown | Phase 3 | 290 | Sun Yat-sen UniversityOTHER | 1 | May 28, 2020 | clinicaltrials |
| NCT04316039 | Radiotherapy Versus Radiotherapy Combined With Temozolomide in High-risk Low-grade Gliomas After Surgery | recruiting | Phase 2 / Phase 3 | 250 | West China HospitalOTHER | 1 | Mar 20, 2020 | clinicaltrials |
| NCT04277221 | ADCTA for Adjuvant Immunotherapy in Standard Treatment of Recurrent Glioblastoma Multiforme (GBM) | unknown | Phase 3 | 118 | Safe Save Medical Cell Sciences & Technology Co.,Ltd.INDUSTRY | 1 | Mar 17, 2020 | clinicaltrials |
| NCT00500890 | Treatment of Tumors of the Choroid Plexus Epithelium | terminated | Phase 3 | 2 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 27, 2020 | clinicaltrials |
| NCT02414165 | The Toca 5 Trial: Toca 511 & Toca FC Versus Standard of Care in Patients With Recurrent High Grade Glioma(Toca5) | terminated | Phase 2 / Phase 3 | 403 | Tocagen Inc.INDUSTRY | 4 | Feb 7, 2020 | clinicaltrials |
| NCT04244708 | The Effect of Chemoradiotherapy in Patients With Refractory Pituitary Adenomas | unknown | Phase 2 / Phase 3 | 150 | Peking Union Medical College HospitalOTHER | 0 | Jan 28, 2020 | clinicaltrials |
| NCT03015701 | S9005 Mifepristone in Meningioma | completed | Phase 3 | 193 | SWOG Cancer Research NetworkNETWORK | 0 | Dec 23, 2019 | clinicaltrials |
| NCT03722355 | Hyperfractionated RT With BCNU Versus Conventional RT With BCNU for Supratentorial Malignant Glioma | completed | Phase 3 | 712 | Radiation Therapy Oncology GroupNETWORK | 0 | Nov 12, 2019 | clinicaltrials |
| NCT00295815 | Enzastaurin Versus Lomustine in Glioblastoma | completed | Phase 3 | 397 | Eli Lilly and CompanyINDUSTRY | 14 | Sep 12, 2019 | clinicaltrials |
| NCT01014767 | Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors | terminated | Phase 3 | 27 | Tufts Medical CenterOTHER | 4 | Aug 20, 2019 | clinicaltrials |
| NCT04058704 | A Study to Determine the Efficiency For Brain Metastasis NSCLC Patients Treated With Icotinib Alone or Combined With Radiation Therapy(SMART) | unknown | Phase 3 | 296 | Betta Pharmaceuticals Co., Ltd.INDUSTRY | 1 | Aug 15, 2019 | clinicaltrials |
| NCT00884741 | Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma | completed | Phase 3 | 637 | National Cancer Institute (NCI)NIH | 3 | Jul 24, 2019 | clinicaltrials |
| NCT03778541 | HFSRT With Concurrent TMZ for Large BMs | unknown | Phase 3 | 224 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 23, 2019 | clinicaltrials |
| NCT03733327 | BUCYE Conditioning Regimen for PCNSL Undergoing Auto-HSCT | unknown | Phase 2 / Phase 3 | 20 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Nov 7, 2018 | clinicaltrials |
| NCT02511405 | A Phase 3, Pivotal Trial of VB-111 Plus Bevacizumab vs. Bevacizumab in Patients With Recurrent Glioblastoma (GLOBE)(GLOBE) | completed | Phase 3 | 252 | Vascular Biogenics Ltd. operating as VBL TherapeuticsINDUSTRY | 3 | Oct 23, 2018 | clinicaltrials |
| NCT00085098 | Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor | completed | Phase 3 | 24 | Children's Oncology GroupNETWORK | 4 | Sep 7, 2018 | clinicaltrials |
| NCT03633552 | Efficacy of Two Temozolomide Regimens in Adjuvant Treatment of Patients With Brain High Grade Glioma | unknown | Phase 3 | 62 | Mashhad University of Medical SciencesOTHER | 1 | Aug 16, 2018 | clinicaltrials |
| NCT00749723 | Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children(HIT-REZ-2005) | completed | Phase 2 / Phase 3 | 174 | University Hospital, BonnOTHER | 1 | Jul 20, 2018 | clinicaltrials |
| NCT00096265 | Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer | terminated | Phase 3 | 126 | National Cancer Institute (NCI)NIH | 2 | Mar 9, 2018 | clinicaltrials |
| NCT01765088 | A Phase III Trial on Adjuvant Temozolomide With or Without Interferon-alpha in Newly Diagnosed High-grade Gliomas | unknown | Phase 3 | 300 | Sun Yat-sen UniversityOTHER | 1 | Feb 23, 2018 | clinicaltrials |
| NCT02629757 | A Study on β-elemene as Maintain Treatment for Newly Diagnosed Malignant Gliomas(β-elemene) | unknown | Phase 3 | 100 | Sun Yat-sen UniversityOTHER | 1 | Feb 23, 2018 | clinicaltrials |
| NCT01601314 | Perioperative Magnesium Sulphate as a Cerebral Protector in Neurosurgical Patients(MAGNA) | completed | Phase 3 | 55 | Sara VareaOTHER | 1 | Jan 17, 2018 | clinicaltrials |
Data updated 22 days agoSource updated May 18, 2022source: clinicaltrials