Subtype
Brain Neoplasm
CI-CAN-00002030Explore in graph →
Non-malignant511 active trials34 evidence items
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Subtype
CI-CAN-00002030Explore in graph →
Clinical trials
2,117 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04755920 | SGM-101 in Colorectal Brain Metastases.(SGM-CBM) | unknown | Phase 2 | 10 | Leiden University Medical CenterOTHER | 1 | May 9, 2024 | clinicaltrials |
| NCT06210438 | SHR-A1921 Combined With Bevacizumab in Triple-negative Breast Cancer With Brain Metastases | unknown | Phase 2 | 24 | Fudan UniversityOTHER | 1 | Jan 18, 2024 | clinicaltrials |
| NCT06186440 |
| Cisplatin Plus Temozolomide Compared With Temozolomide in Patients With MGMT Promotor Unmethylated Glioblastoma(Glioblastoma) |
| unknown |
| Phase 1 / Phase 2 |
| 60 |
| Zhongnan HospitalOTHER |
| 0 |
| Jan 2, 2024 |
| clinicaltrials |
| NCT03620032 | Study of Re-irradiation at Relapse Versus RT and Multiple Elective rt Courses(DIPG) | unknown | Phase 2 | 54 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Dec 6, 2023 | clinicaltrials |
| NCT05812534 | Study of Cadonilimab Combined With Bevacizumab and Chemotherapy for Advanced Nonsquamous Non-small Cell Lung Cancer Patients With Untreated Brain Metastases(CBC) | unknown | Phase 2 | 36 | Second Affiliated Hospital of Nanchang UniversityOTHER | 0 | Nov 18, 2023 | clinicaltrials |
| NCT03951142 | Imaging Perfusion Restrictions From Extracellular Solid Stress - An Open-label Losartan Study(ImPRESS) | unknown | Phase 2 | 165 | Kyrre Eeg EmblemOTHER | 1 | Nov 1, 2023 | clinicaltrials |
| NCT02137759 | MRSI to Predict Response to RT/TMZ ± Belinostat in GBM | unknown | Phase 2 | 29 | Emory UniversityOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT04211090 | Camrelizumab With AC in Patients With Brain Metastases of Driven Gene-negative,NSCLC(CAP-BRAIN) | unknown | Phase 2 | 45 | Sun Yat-sen UniversityOTHER | 1 | Nov 16, 2022 | clinicaltrials |
| NCT05084092 | IORT After Surgical Resection of Brain Metastases(IORT_BRAINM1) | unknown | Phase 2 | 40 | Institut Català d'OncologiaOTHER | 1 | Aug 4, 2022 | clinicaltrials |
| NCT05177185 | Hippocampal-Sparing Stereotactic Radiosurgery Treatment of Brain Metastases Using CyberKnife(HiSparCK) | unknown | Phase 2 | 70 | Ottawa Hospital Research InstituteOTHER | 0 | Feb 16, 2022 | clinicaltrials |
| NCT05207904 | Tislelizumab Plus Chemotherapy as First-Line Treatment for Advanced Squamous NSCLC With Brain Metastases | unknown | Phase 2 | 41 | Sun Yat-sen UniversityOTHER | 1 | Jan 26, 2022 | clinicaltrials |
| NCT05125666 | Efficacy of Dual Task Training on Children With Ataxia After Medulloblastoma Resection | unknown | Phase 2 | 30 | Cairo UniversityOTHER | 1 | Nov 18, 2021 | clinicaltrials |
| NCT00983398 | Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors | unknown | Phase 1 / Phase 2 | 17 | OHSU Knight Cancer InstituteOTHER | 1 | Oct 26, 2021 | clinicaltrials |
| NCT03932981 | First-line Chemotherapy With Temozolomide Alone for Non-enhancing Adult Brainstem Gliomas, With a Diffuse Subtype and Showing Clinical and/or Radiological Infiltrative Pattern of Progression(TEMOTRAD01) | unknown | Phase 2 | 60 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Sep 10, 2021 | clinicaltrials |
| NCT04760431 | TKIs vs. Pertuzumab in HER2+ Breast Cancer Patients With Active Brain Metastases (HER2BRAIN) | unknown | Phase 2 | 120 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jun 2, 2021 | clinicaltrials |
| NCT03025893 | A Phase II/III Study of High-dose, Intermittent Sunitinib in Patients With Recurrent Glioblastoma Multiforme(STELLAR) | unknown | Phase 2 / Phase 3 | 100 | Amsterdam UMC, location VUmcOTHER | 1 | Apr 19, 2021 | clinicaltrials |
| NCT04801342 | Neurocognitive Outcome of Bilateral or Unilateral Hippocampal Avoidance WBRT With Memantine for Brain Metastases | unknown | Phase 2 | 72 | National Taiwan University HospitalOTHER | 1 | Mar 17, 2021 | clinicaltrials |
| NCT04675008 | Central Nervous System(CNS) Efficacy of Dacomitinib | unknown | Phase 2 | 30 | Samsung Medical CenterOTHER | 1 | Jan 5, 2021 | clinicaltrials |
| NCT04668508 | Anlotinib to Malignant Brainstem Glioma | unknown | Phase 2 | 25 | Zhejiang Cancer HospitalOTHER | 1 | Dec 16, 2020 | clinicaltrials |
| NCT04158947 | A Study of HER2+ Breast Cancer Patients With Active Brain Metastases Treated With Afatinib & T-DM1 vs. T-DM1 Alone(HER2BAT) | unknown | Phase 2 | 130 | xuexin heOTHER | 1 | May 12, 2020 | clinicaltrials |
| NCT04335357 | TBR-760 in Adult Patients With Non-Functioning Pituitary Adenomas | unknown | Phase 2 | 150 | Tiburio TherapeuticsINDUSTRY | 0 | Apr 6, 2020 | clinicaltrials |
| NCT00798811 | High-dose Chemotherapy With Autologous Stem Cell Rescue in Pediatric High-risk Brain Tumors | unknown | Phase 2 | 100 | Samsung Medical CenterOTHER | 1 | Mar 19, 2020 | clinicaltrials |
| NCT04244708 | The Effect of Chemoradiotherapy in Patients With Refractory Pituitary Adenomas | unknown | Phase 2 / Phase 3 | 150 | Peking Union Medical College HospitalOTHER | 0 | Jan 28, 2020 | clinicaltrials |
| NCT04213170 | Sintilimab Combined With Bevacizumab for Brain Metastases From Non-small Cell Lung Cancer | unknown | Phase 2 | 60 | Sun Yat-sen UniversityOTHER | 1 | Dec 30, 2019 | clinicaltrials |
| NCT04193007 | The Role of Brain Radiotherapy in Patients With Asymptomatic Brain Metastasis in the Era of Targeted Therapy for NSCLC(BRATR) | unknown | Phase 2 | 100 | Second Affiliated Hospital of Nanchang UniversityOTHER | 1 | Dec 10, 2019 | clinicaltrials |
| NCT04180501 | SRS Sequential Sindilimab in Brain Metastasis of NSLSC | unknown | Phase 2 | 25 | Xiaorong DongOTHER | 1 | Nov 27, 2019 | clinicaltrials |
| NCT03916757 | V-Boost Immunotherapy in Glioblastoma Multiforme Brain Cancer(GBM) | unknown | Phase 2 | 20 | Immunitor LLCINDUSTRY | 1 | Apr 17, 2019 | clinicaltrials |
| NCT02726568 | High Dose Icotinib With Sequential SRS For NSCLC Patients Harboring EGFR Mutation With Brain Metastases | unknown | Phase 2 | 30 | Betta Pharmaceuticals Co., Ltd.INDUSTRY | 1 | Feb 19, 2019 | clinicaltrials |
| NCT03754530 | Icotinib Combined With Radiation Therapy For NSCLC Patients With Brain Metastases and EGFR Mutation | unknown | Phase 2 | 162 | Betta Pharmaceuticals Co., Ltd.INDUSTRY | 0 | Nov 27, 2018 | clinicaltrials |
| NCT02672241 | Nimotuzumab in Combination With Radio-chemotherapy for the Treatment of Brainstem Tumor in Children | unknown | Phase 2 | 30 | Xinhua Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 1 | Oct 16, 2018 | clinicaltrials |
| NCT02233049 | Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication(BIOMEDE) | unknown | Phase 2 | 250 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Jul 23, 2018 | clinicaltrials |
| NCT02655536 | Bevacizumab and Erlotinib in Lung Cancer With Brain Metastases, a Phase II Trial(BRILLIANT) | unknown | Phase 2 | 109 | National Taiwan University HospitalOTHER | 1 | Jul 10, 2018 | clinicaltrials |
| NCT01857453 | Interest of a Dose Decrease for Radiotherapy Associated With Chemotherapy for Treatment of Standard Risk Adult Medulloblastomas(RSMA2010) | unknown | Phase 2 | 97 | Central Hospital, Nancy, FranceOTHER | 1 | Jul 5, 2018 | clinicaltrials |
| NCT03356600 | Apatinib Plus Radiotherapy for Patients With Brain Metastases From Non-small-cell Lung Cancer | unknown | Phase 2 | 44 | Shanxi Province Cancer HospitalOTHER | 0 | Dec 11, 2017 | clinicaltrials |
| NCT03366376 | Hippocampus-sparing WBRT and Simultaneous Integrated Boost for Multiple Brain Metastases From NSCLC(KROG17-06) | unknown | Phase 2 | 80 | Samsung Medical CenterOTHER | 1 | Dec 8, 2017 | clinicaltrials |
| NCT03294486 | Safety and Efficacy of the ONCOlytic VIRus Armed for Local Chemotherapy, TG6002/5-FC, in Recurrent Glioblastoma Patients(ONCOVIRAC) | unknown | Phase 1 / Phase 2 | 78 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Nov 6, 2017 | clinicaltrials |
| NCT03216148 | 18F-FET PET in Childhood Brain Tumours | unknown | Phase 2 | 160 | Charite University, Berlin, GermanyOTHER | 1 | Jul 21, 2017 | clinicaltrials |
| NCT01952769 | Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma | unknown | Phase 1 / Phase 2 | 50 | Hadassah Medical OrganizationOTHER | 1 | Sep 13, 2016 | clinicaltrials |
| NCT02681705 | Radiation Therapy and Combination Chemotherapy for Medulloblastoma | unknown | Phase 2 | 60 | Xinhua Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 1 | Aug 17, 2016 | clinicaltrials |
| NCT02832635 | A Clinical Trial on Whole-brain Radiotherapy With Temozolomide Concurrent Chemotherapy or Avoidance of Hippocampus for Patients of Brain Metastases | unknown | Phase 2 | 256 | Sun Yat-sen UniversityOTHER | 1 | Jul 14, 2016 | clinicaltrials |
| NCT02338011 | Comparator-Controlled Study for EGFR(+) Patients With Multiple BMs From NSCLC (BROKE) (EGFR-epidermal Growth Factor Receptor;BM-brain Metastases)(EGFR) | unknown | Phase 2 / Phase 3 | 210 | Shanghai Chest HospitalOTHER | 1 | Jan 26, 2015 | clinicaltrials |
| NCT01763385 | Erlotinib With Concurrent Brain Radiotherapy and Secondary Brain Radiotherapy After Recurrence With Erlotinib in NSCLC Non-increased-intracranial-pressure Symptomatic Brain Metastases(TRACTS) | unknown | Phase 2 | 210 | Wu Jieping Medical FoundationOTHER | 1 | Dec 23, 2014 | clinicaltrials |
| NCT02284490 | High-dose Pemetrexed to Treat Lung Adenocarcinoma With Brain Metastases | unknown | Phase 2 | 25 | Rongjie TaoOTHER | 1 | Nov 6, 2014 | clinicaltrials |
| NCT01535183 | Irinotecan Combination Chemotherapy for Refractory or Relapsed Brain Tumor in Children and Adolescents | unknown | Phase 2 | 40 | Seoul National University HospitalOTHER | 1 | Jul 14, 2014 | clinicaltrials |
| NCT01342237 | Tandem High Dose Chemotherapy and Autologous Stem Cell Rescue for High Risk Pediatric Brain Tumors | unknown | Phase 2 | 33 | Seoul National University HospitalOTHER | 1 | Nov 19, 2013 | clinicaltrials |
| NCT01640509 | Synchrotron Radiation to the Treatment of Intracranial Tumors(ESRF) | unknown | Phase 1 / Phase 2 | 50 | University Hospital, GrenobleOTHER | 1 | Nov 11, 2013 | clinicaltrials |
| NCT01410370 | Continuous Endostar Infusion Combined With Radiotherapy in Patients With Brain Metastases | unknown | Phase 2 | 80 | Jiangsu Simcere Pharmaceutical Co., Ltd.INDUSTRY | 1 | Apr 24, 2013 | clinicaltrials |
| NCT01688713 | Phase II Trial of Double Dose of Icotinib in Treating Brain Metastases From Non-small Cell Lung Cancer | unknown | Phase 2 | 20 | Zhejiang Cancer HospitalOTHER | 1 | Sep 20, 2012 | clinicaltrials |
| NCT01476878 | Frameless Stereotactic Radiosurgery for Brain Metastases | unknown | Phase 1 / Phase 2 | 20 | Alberta Health servicesOTHER | 1 | Nov 22, 2011 | clinicaltrials |
Data updated 22 days agoSource updated May 9, 2024source: clinicaltrials